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“Statistical Challenges with Making Super IQ babies” by Jan Christian Refsgaard
Manage episode 469733029 series 3364758
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This is a critique of How to Make Superbabies on LessWrong.
Disclaimer: I am not a geneticist[1], and I've tried to use as little jargon as possible. so I used the word mutation as a stand in for SNP (single nucleotide polymorphism, a common type of genetic variation).
Background
The Superbabies article has 3 sections, where they show:
Outline:
(00:25) Background
(02:25) My Position
(04:03) Correlation vs. Causation
(06:33) The Additive Effect of Genetics
(10:36) Regression towards the null part 1
(12:55) Optional: Regression towards the null part 2
(16:11) Final Note
The original text contained 4 footnotes which were omitted from this narration.
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First published:
March 2nd, 2025
Source:
https://www.lesswrong.com/posts/DbT4awLGyBRFbWugh/statistical-challenges-with-making-super-iq-babies
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Narrated by TYPE III AUDIO.
…
continue reading
Disclaimer: I am not a geneticist[1], and I've tried to use as little jargon as possible. so I used the word mutation as a stand in for SNP (single nucleotide polymorphism, a common type of genetic variation).
Background
The Superbabies article has 3 sections, where they show:
- Why: We should do this, because the effects of editing will be big
- How: Explain how embryo editing could work, if academia was not mind killed (hampered by institutional constraints)
- Other: like legal stuff and technical details.
- we can already make (slightly) superbabies selecting embryos with "good" mutations, but this does not scale as there are diminishing returns and almost no gain past "best [...]
Outline:
(00:25) Background
(02:25) My Position
(04:03) Correlation vs. Causation
(06:33) The Additive Effect of Genetics
(10:36) Regression towards the null part 1
(12:55) Optional: Regression towards the null part 2
(16:11) Final Note
The original text contained 4 footnotes which were omitted from this narration.
---
First published:
March 2nd, 2025
Source:
https://www.lesswrong.com/posts/DbT4awLGyBRFbWugh/statistical-challenges-with-making-super-iq-babies
---
Narrated by TYPE III AUDIO.
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