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Harnessing Proteoforms to Understand Life's Complexity
Manage episode 424482453 series 3566384
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Proteins are far more than just the output of genes. They can be modified in myriad ways to produce millions of proteoforms with altered dynamics, localization, and function. For a comprehensive understanding of biology that will propel drug development and biomarker discovery forward, we need to be able to measure proteoforms routinely. In this episode, Parag and Andreas discuss the incredible value that will come from studying proteoforms and describe what it will take to make proteoform measurement a routine part of biology research.
Chapters:
00:00 - Introduction to proteoforms
09:38 - Evidence that proteoforms are important and how we can use proteoform data
19:28 - Technology advances needed to understand proteoform biology
10 episodi
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