The BMJ brings you interviews with the people who are shaping medicine and science around the world.
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Flash Forward is a show about possible (and not so possible) future scenarios. What would the warranty on a sex robot look like? How would diplomacy work if we couldn’t lie? Could there ever be a fecal transplant black market? (Complicated, it wouldn’t, and yes, respectively, in case you’re curious.) Hosted and produced by award winning science journalist Rose Eveleth, each episode combines audio drama and journalism to go deep on potential tomorrows, and uncovers what those futures might re ...
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As She Rises brings together local poets and activists from throughout North America to depict the effects of climate change on their home and their people. Each episode carries the listener to a new place through a collection of voices, local recordings and soundscapes. Stories span from the Louisiana Bayou, to the tundras of Alaska to the drying bed of the Colorado River. Centering the voices of native women and women of color, As She Rises personalizes the elusive magnitude of climate cha ...
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Concise summaries of everything published in the latest weekly issue of the New England Journal of Medicine (NEJM). NEJM publishes new medical research findings, review articles, and editorial opinion on topics of importance to biomedical science and clinical practice.
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Come dive into one of the curiously delightful conversations overheard at National Geographic’s headquarters, as we follow explorers, photographers, and scientists to the edges of our big, weird, beautiful world. Hosted by Peter Gwin and Amy Briggs.
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This Week in Evolution is a podcast on the biology of what makes us tick. Hosts Nels Elde and Vincent Racaniello take you through the new evolution that has been revolutionized by the field of genomics and molecular biology.
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Read along with the Sword and Laser book club! From classic science fiction to the latest gritty fantasy, we cover it. Subscribe for book discussions, author interviews, hot releases, and news from the genre fiction world!
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Discussions about the science of nutrition, dietetics and health. The podcast that educates through nuanced conversations, exploring evidence and cultivating critical thinking. Hosted by Danny Lennon.
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Science Friction's latest series is: Cooked. We dig into food science pickles. Why are studies showing that ice cream could be good for you? Do we really need as many electrolytes as the internet says? And why are people feeling good on the carnivore diet? Nutrition and food scientist Dr Emma Beckett takes us through what the evidence says about foods like meat, ice cream and potatoes — and unpicks why nutrition studies can be so conflicting and confusing. All six episodes of Cooked are avai ...
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Going Wild with Dr. Rae Wynn Grant is a different kind of nature show about the human drama of saving animals. From a paleoanthropologist who hunts fossils in conflict zones to someone who helped save an endangered species while in prison, in season four we will hear from real-life heroes and nature advocates with widely different expertise and life experiences that led them to be champions for the natural world. Wildlife biologist and host Dr. Rae Wynn-Grant has been studying wild animals i ...
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We made it— 300 episodes of This Is Woman’s Work ! And we’re marking this milestone by giving you something that could seriously change the game in your business or career: the skill of pitching yourself effectively. Whether you’re dreaming of being a podcast guest, landing a speaking gig, signing a client, or just asking for what you want with confidence—you’re already pitching yourself, every day. But are you doing it well? In this milestone episode, Nicole breaks down exactly how to pitch yourself to be a podcast guest … and actually hear “yes.” With hundreds of pitches landing in her inbox each month, she shares what makes a guest stand out (or get deleted), the biggest mistakes people make, and why podcast guesting is still one of the most powerful ways to grow your reach, authority, and influence. In This Episode, We Cover: ✅ Why we all need to pitch ourselves—and how to do it without feeling gross ✅ The step-by-step process for landing guest spots on podcasts (and more) ✅ A breakdown of the 3 podcast levels: Practice, Peer, and A-List—and how to approach each ✅ The must-haves of a successful podcast pitch (including real examples) ✅ How to craft a pitch that gets read, gets remembered, and gets results Whether you’re new to pitching or want to level up your game, this episode gives you the exact strategy Nicole and her team use to land guest spots on dozens of podcasts every year. Because your voice deserves to be heard. And the world needs what only you can bring. 🎁 Get the FREE Podcast Pitch Checklist + Additional Information on your Practice Group, Peer Group, and A-List Group Strategies: https://nicolekalil.com/podcast 📥 Download The Podcast Pitch Checklist Here Related Podcast Episodes: Shameless and Strategic: How to Brag About Yourself with Tiffany Houser | 298 How To Write & Publish A Book with Michelle Savage | 279 How To Land Your TED Talk and Skyrocket Your Personal Brand with Ashley Stahl | 250 Share the Love: If you found this episode insightful, please share it with a friend, tag us on social media, and leave a review on your favorite podcast platform! 🔗 Subscribe & Review: Apple Podcasts | Spotify | Amazon Music…
Can Aging be Reversed? Stem Cells as a Key to Longevity
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Curious about what happens to our cells as we age and how it affects our health? Shiri Gur-Cohen explores the role of tiny chemical tags on our DNA, like methylation, in influencing our healing and overall well-being. Gur-Cohen discusses how these tags might be shaped by our body's systems, such as the lymphatic system, and could even help repair or regenerate various parts of our body. Gur-Cohen proposes that uncovering these processes could lead to innovative ways to slow aging or boost our body’s natural healing capabilities. Series: "Women in Science" [Health and Medicine] [Science] [Show ID: 39979]
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100 episodi
CondividiManage episode 441438590 series 3381199
Contenuto fornito da UCTV. Tutti i contenuti dei podcast, inclusi episodi, grafica e descrizioni dei podcast, vengono caricati e forniti direttamente da UCTV o dal partner della piattaforma podcast. Se ritieni che qualcuno stia utilizzando la tua opera protetta da copyright senza la tua autorizzazione, puoi seguire la procedura descritta qui https://it.player.fm/legal.
Curious about what happens to our cells as we age and how it affects our health? Shiri Gur-Cohen explores the role of tiny chemical tags on our DNA, like methylation, in influencing our healing and overall well-being. Gur-Cohen discusses how these tags might be shaped by our body's systems, such as the lymphatic system, and could even help repair or regenerate various parts of our body. Gur-Cohen proposes that uncovering these processes could lead to innovative ways to slow aging or boost our body’s natural healing capabilities. Series: "Women in Science" [Health and Medicine] [Science] [Show ID: 39979]
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Karen Christman, Sheila Chari, Stella Hurtley, and Robert Stephenson explore academic publishing in stem cell research, focusing on reproducibility, collaboration, and public communication. Editors from top journals discuss curating impactful research, sharing clinical trial data, and addressing challenges in scaling and standardizing therapies. They emphasize bridging silos, advancing precision regenerative medicine, and navigating open access publishing to responsibly propel the field forward. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39940]…
1 The Future of Precision Medicine: Stem Cells Gene Therapy and AI - Medicine Informing Novel Discoveries (MIND) 57:36
Learn about advancements in precision medicine, particularly the role of AI, stem cell research, and gene therapy. Experts highlight AI’s potential in personalized treatments, diagnostics, and patient care. Key topics include RNA targeting therapies, base editing for gene mutations, and using stem cells for disease modeling and regeneration. AI’s contribution to enhancing healthcare efficiency and decision-making is also explored, emphasizing its role in personalized medicine through large data sets. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39981]…
1 Uncovering Mechanisms of Neurodegenerative Diseases by CRISPR-Based Screens with Martin Kampmann 58:22
Martin Kampmann, Ph.D., explores how CRISPR screening and induced pluripotent stem cell (iPSC) technology can uncover new insights into neurological diseases such as Alzheimer's. His lab uses CRISPR to identify genes that influence protein aggregation and cellular vulnerability, focusing on neurons, astrocytes, and microglia derived from human stem cells. Kampmann highlights the roles of mitochondria, autophagy, and other cellular pathways in disease progression, emphasizing the importance of understanding both protective and damaging processes. He also discusses the potential contributions of glial cells—especially microglia and astrocytes—to neurodegeneration, sparking ideas for therapeutic targets. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39461]…
Frank Furnari, Ph.D., and Alexander Khalessi, M.D., M.B.A., discuss exciting advancements in brain cancer research, focusing on glioblastoma, an aggressive and challenging tumor. They highlight how specific genetic mutations drive tumor growth and how targeting these mutations could lead to new treatments. They also delve into cutting-edge therapies, including using light to activate drugs aimed at combating cancer. A central theme of the talk is the complexity and ever-changing nature of these tumors, which makes them difficult to treat. However, technological breakthroughs, like single-cell genetic sequencing and lab-grown tumor models, are providing scientists with valuable insights into tumor behavior, paving the way for more personalized and effective treatment options in the future. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39871]…
Le Xu, Ph.D., examines the intricate processes underlying lung development and disease, with a focus on idiopathic pulmonary fibrosis (IPF). Xu explores the roles of genetic and cellular mechanisms, including the hedgehog pathway, FGF signaling, and epithelial-mesenchymal interactions, in driving lung fibrosis. Xu also highlights links between congenital diaphragmatic hernia (CDH) and lung development, suggesting that both mechanical and genetic factors contribute to lung hypoplasia. The discussion includes the development of advanced mouse models that replicate key aspects of human IPF, offering insights into fibrosis progression. Xu's research ultimately seeks to identify the causes of lung tissue abnormalities and pave the way for targeted therapies. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39460]…
1 Restoration of T Cell Development in CD3δ SCID Through Adenine Base-Editing with Gloria Yiu - Sanford Stem Cell Symposium 2024 28:12
Gloria Yiu, M.D., Ph.D., delves into the transformative potential of genetic editing technologies in addressing rare immune disorders, with a focus on CD3δ severe combined immunodeficiency (SCID)—a condition characterized by impaired T-cell development and severely compromised immune function. Leveraging her expertise as a physician-scientist, Yiu explores how CRISPR and other precision gene-editing tools can correct genetic mutations at the cellular level, potentially restoring T-cell production and immune resilience in patients with CD3δ SCID. Her presentation underscores the challenges and breakthroughs in treating such life-threatening conditions, emphasizing the role of interdisciplinary research, clinical innovation, and ethical considerations in advancing the frontiers of personalized medicine. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 40245]…
The infections disease landscape is constantly changing - challenging our standard treatments. Can new - as well as ancient - therapies be the answer? Hear from experts on the cutting edge of phage therapy, HIV/AIDS research and cancer care about what is on the horizon to improve human health. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39982]…
1 What Makes a Stem Cell a Stem Cell and How Does it Go Bad? with John Dick - Sanford Stem Cell Symposium 2024 45:32
John Dick, Ph.D., F.R.S., explores the role of CD83, a molecule found in blood stem cells, in how these cells respond to inflammation. His team demonstrates that CD83 becomes highly active during inflammation and contributes to the loss of healthy stem cells. Using advanced gene-editing tools, they show that removing CD83 protects stem cells from inflammation-related damage. This discovery highlights CD83 as a potential marker for identifying inflamed stem cells and as a possible target for treatments to improve recovery after stem cell transplants. He also discusses early findings on potential differences in blood stem cell behavior between men and women and raises questions about how inflammation from severe illnesses, like COVID-19, could impact the blood system as we age. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39949]…
1 Space-Based Research: Predicting and Preventing Accelerated Stem Cell Aging and Cancer Evolution with Catriona Jamieson - Sanford Stem Cell Symposium 2024 28:29
Catriona Jamieson, M.D., Ph.D., discusses pioneering research on cancer and aging in space environments, highlighting how microgravity accelerates cancer cell growth and leads to stem cell exhaustion, genomic instability, and “dark genome” activation. Using innovative tools like nano-bioreactors and artificial intelligence, her team simulates these effects and tracks cellular changes, uncovering how space’s unique conditions drive mutations and alter cellular behavior. They find that stem cells rapidly proliferate but then become exhausted in space, a process tied to telomere shortening and mitochondrial stress, impacting cell longevity and regenerative potential. Through collaborations with NASA and industry partners, Jamieson’s research aims to develop therapies to counter these effects, offering potential insights for cancer treatment and stem cell health on Earth. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39948]…
1 Explorations of Telomere Biology in the Context of Human Aging with Elizabeth Blackburn - Sanford Stem Cell Symposium 2024 45:17
Elizabeth Blackburn, Ph.D., examines the relationship between telomeres, cellular aging, and metabolic health, highlighting how telomere regulation differs between insulin-sensitive and insulin-resistant individuals. She discusses the effects of environmental factors—like glucose levels, stress hormones, and drugs—on telomere maintenance, which can disrupt cellular coordination and contribute to age-related diseases. Blackburn also shares insights from studies on hibernating lemurs, indicating that while their telomere health remains stable during metabolic slowdowns, it declines upon reactivation. Ultimately, she suggests that telomere maintenance could serve as a valuable biomarker for early signs of metabolic dysfunction, informing strategies for long-term health and resilience. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39944]…
1 Found in Translation: Development of a Cellular Therapy for Age-Related Macular Degeneration 1:12:41
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Riproduci in seguito Riproduci in seguito Liste Like Like aggiuntoDennis O. Clegg, Ph.D., discusses treatments for age-related macular degeneration (AMD), a condition that causes vision loss. Clegg explains that while patients often report improved vision after receiving implants, objective tests don't always confirm this. He explores the potential differences in patients' responses based on genetics and disease progression. There is also an ongoing challenge in finding the best ways to reduce immune rejection of these treatments. New trials are underway to test implants in earlier stages of the disease, and researchers are looking at different strategies like localized immunosuppression. Additionally, some studies suggest that secretions from retinal cells may help preserve vision. Overall, there are many open questions, but advances in the field offer hope for better AMD treatments. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39459]…
Curious about the secret to staying young? Rob Signer shares insights into how our bodies age, focusing on the role of stem cells and a critical protein called HSF1 that helps them cope with stress. Signer explores the delicate balance of keeping these cells healthy without increasing cancer risk and highlighted some promising progress in enhancing the cells' ability to manage waste. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39980]…
1 Stem Cells and the Human Brain - Medicine Informing Novel Discoveries (MIND) 1:04:09
1:04:09 Riproduci in seguito Riproduci in seguito Liste Like Like aggiunto1:04:09
Riproduci in seguito Riproduci in seguito Liste Like Like aggiuntoExplore the captivating realm of brain research at UC San Diego with Frank Furnari, Ph.D., and Alexander Khalessi, M.D., M.B.A. Furnari and Khalessi delve into groundbreaking efforts to find new treatments for neurological conditions such as brain tumors, stroke, and brain injuries, bringing hope to patients and their families. Emphasizing ethics, innovation, and patient care, Furnari and Khalessi shed light on the challenges and successes in their quest to unravel the mysteries of the mind. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39723]…
1 Bioengineering a Kidney Chip for Better Safer and Faster Drug Development 1:11:02
1:11:02 Riproduci in seguito Riproduci in seguito Liste Like Like aggiunto1:11:02
Riproduci in seguito Riproduci in seguito Liste Like Like aggiuntoCatherine Yeung, Pharm.D., Ph.D., M.P.H., discusses groundbreaking advancements in kidney-on-a-chip technology, emphasizing its potential to revolutionize human health. She delves into the role of environmental toxins, such as okra toxin A, microplastics, and plasticizers, in contributing to chronic kidney disease, particularly in regions with specific dietary practices. Yeung also addresses the challenges of replicating adult kidney cells from stem cells, which often retain a fetal phenotype, and underscores the value of stem cell-derived models for genetic manipulation and disease research. Additionally, she highlights the increased risk of kidney stones in astronauts post-spaceflight and the broader implications of organ-on-chip technology for studying therapies and diseases. Series: "Women in Science" [Health and Medicine] [Science] [Show ID: 39458]…
Curious about what happens to our cells as we age and how it affects our health? Shiri Gur-Cohen explores the role of tiny chemical tags on our DNA, like methylation, in influencing our healing and overall well-being. Gur-Cohen discusses how these tags might be shaped by our body's systems, such as the lymphatic system, and could even help repair or regenerate various parts of our body. Gur-Cohen proposes that uncovering these processes could lead to innovative ways to slow aging or boost our body’s natural healing capabilities. Series: "Women in Science" [Health and Medicine] [Science] [Show ID: 39979]…
Michael Lane, Ph.D., shares his work investigating the effects of cervical spinal cord injury (SCI) on breathing and upper extremity function, focusing on the potential for spontaneous functional recovery, or "plasticity." Lane also discusses efforts to develop and test strategies to promote beneficial plasticity and recovery following cervical SCI, with a particular emphasis on improving respiratory function and activity in respiratory muscles. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39457]…
Giorgia Quadrato, Ph.D., explores cerebral organoids as models for neural development and disease research. Using live calcium imaging, Quadrato observes increased neuronal coordination attributed to inhibitory neurons, validated through pharmacological and genetic methods. Quadrato contrasts their organoid generation protocol with previous methods, emphasizing complex patterning, long-term cultures, and co-culture with mouse brain cells for improved physiological relevance. Microfluidics are utilized for enhanced oxygenation and physiological conditions. Future efforts focus on incorporating microglial cells for synaptic pruning studies and overcoming challenges in cryopreservation. Overall, the research aims to advance understanding of neural mechanisms and diseases, enhancing organoid fidelity for biomedical applications. Series: "Women in Science" [Health and Medicine] [Science] [Show ID: 39456]…
1 Modeling Kidney Disease and Regeneration with Organoids Derived from Human Pluripotent Stem Cells 56:20
Benjamin Freedman, Ph.D., delves into the creation and functionality of kidney organoids. He discusses their focus on filtration over hormone functions, and answers intriguing questions about urine characterization and the necessity of organoid structures. Freedman explores the use of scaffolds for implants and ponders the philosophical implications of off-target cells in organoids, questioning whether these cells are a natural part of organ development. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39455]…
Can we live not only longer but healthier lives? Robert A.J. Signer and Shiri Gur-Cohen explore how stem cell research may unlock the secrets of longevity. Signer discusses the critical role stem cells play in combating aging-related diseases, such as cancer and immune system decline, by boosting their regenerative abilities. His work on hematopoietic stem cells and “super stem cells,” which better manage cellular waste, shows promise for delaying aging and preventing disease. Dr. Shiri Gur-Cohen examines how vascular and lymphatic systems support stem cell health, revealing new strategies for enhancing longevity and reversing the effects of aging. Don’t miss this in-depth look at the future of aging and human health. Series: "Women in Science" [Health and Medicine] [Science] [Show ID: 39869]…
1 Capturing Late-Onset Neurodegeneration in Patient-Derived Neurons via Direct Reprogramming - Breaking News in Stem Cells 59:16
Andrew Yoo, Ph.D., provides insight into the ongoing research on neurodegeneration and neuronal reprogramming, highlighting the complexities and challenges in modeling and understanding these processes. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39454]
Why explore stem cells in space when we have the comfort of Earth's laboratories? Join Robert A.J. Signer, Ph.D., alongside Catriona Jamieson, M.D., Ph.D., and Alysson Muotri, Ph.D., as they delve into the untapped potential of space experiments for expediting medical breakthroughs. Patient advocate Alexandria Allen offers a poignant narrative, revealing the profound impact such research has had on her personal health journey. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39733]…
1 Effects of Astrocytic Circadian Clocks Disruption on Synaptic Pruning with Anca Pasca - Breaking News in Stem Cells 55:20
Medical advances have significantly improved the survival of preterm babies and term neonates with brain injuries due to environmental hypoxia or genetic causes. Anca Pasca, M.D., shares her work to understand the molecular mechanisms underlying neurodevelopmental disorders associated with fetal and neonatal brain injury. Series: "Women in Science" [Health and Medicine] [Science] [Show ID: 39453]…
Explore cutting-edge research at the intersection of neuroscience, space exploration, and medical innovation. Researchers discuss revolutionary experiments with brain organoids cultivated from stem cells, conducted both in terrestrial labs and aboard the International Space Station. They investigate accelerated aging, neuroprotective agents, and potential treatments for conditions like Alzheimer's and ALS. The dialogue also delves into the transformative impact of space environments on scientific discoveries, from understanding bacterial growth to developing novel therapies. Through collaborative efforts, they strive to revolutionize healthcare, offering hope for patients and pushing the boundaries of human knowledge. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39632]…
Marking the one-year anniversary of the Global Astrobiotechnology Hub, an esteemed panel convenes to envision the future of space exploration and stem cell research. Central to their discussion is the imperative to enhance accessibility and expedite scientific inquiry in space. They advocate for a shift towards establishing regular access to space, enabling frequent dispatches of payloads and experiments. They highlight the pressing need to advance technology to democratize space research, opening doors for nontraditional researchers from industry, academia, and beyond. They emphasize the significance of scientist-astronauts who possess a nuanced understanding of research methodologies. Emphasizing the importance of public engagement, they underscore the need to disseminate research findings widely and mentor the upcoming generation of scientists. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39528]…
1 Skin Development and Regeneration in Homeostasis and Disease with Elena Ezhkova - Breaking News in Stem Cells 1:05:49
1:05:49 Riproduci in seguito Riproduci in seguito Liste Like Like aggiunto1:05:49
Riproduci in seguito Riproduci in seguito Liste Like Like aggiuntoElena Ezhkova, Ph.D., discusses the role of Merkel cells in touch sensation and their connection to nerves. She shares research on skin cancer formation, focusing on the PRC1 complex's impact on gene expression. Ezhkova also investigates epithelial-to-mesenchymal transition (EMT), finding it contributes to cancer spread. Ezhkova offers insights for potential cancer treatments. Series: "Women in Science" [Health and Medicine] [Show ID: 38335]…
1 Modeling Development with Stem Cells with Amander Clark - Breaking News in Stem Cells 1:07:59
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Riproduci in seguito Riproduci in seguito Liste Like Like aggiuntoAmander Clark, Ph.D., delves into crafting artificial ovaries for fertility and aging research. She stresses the importance of diversity in stem cell studies to ensure comprehensive findings. By assembling ovarian models from various genetic backgrounds, her team aims for inclusive representation in biomedical research, potentially offering insights into reproductive health and disease. Series: "Women in Science" [Health and Medicine] [Show ID: 38334]…
1 Dissecting Human HSC Self-Renewal Mechanisms Throughout Ontogeny with Hanna Mikkola - Sanford Stem Cell Symposium 2023 33:15
Hanna Mikkola, M.D., Ph.D., shares her work in hematopoietic stem cells (HSCs) and their complex renewal process. Her research aims to unravel these cells' behavior in mice and humans, offering potential insights for future medical advancements. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39258]…
1 Examining the Therapeutic Potential of Stem Cell Derived Microglia with Mathew Blurton-Jones - Breaking News in Stem Cells 1:18:20
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Riproduci in seguito Riproduci in seguito Liste Like Like aggiuntoMathew Blurton-Jones presents CRISPR-based interventions for a rare brain disorder in mice by substituting defective brain cells with healthy ones. He details experiments demonstrating the efficacy of corrected cells in mitigating brain pathologies. Blurton-Jones emphasizes the need for cautious translation to human trials, advocating gradual cell replacement to preempt potential adverse effects. Additionally, he delves into the implications of microglia in Alzheimer's disease progression and explores potential interconnections among various neurodegenerative conditions. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 38333]…
1 Prenatal Inflammation Shapes Postnatal Immune Function by Reprogramming Fetal Hematopoiesis with Anna Beaudin - Sanford Stem Cell Symposium 2023 37:24
Anna Beaudin, Ph.D., delves into the intricacies of how prenatal inflammation impacts the immune system's blueprint, shaping its long-term function. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39257]
1 Working Together for Better Patient Care: Alpha Clinic Directors Panel - Sanford Stem Cell Symposium 2023 56:27
CIRM-funded Alpha Stem Cell Clinics are a network of California medical centers that specialize in delivering stem cell clinical trials to patients. In this fascinating panel, clinic directors discuss advanced treatments, therapies like gene editing, and sharing knowledge and creating networks across the country for better patient care. Featuring: Geoffrey Lomax, Dr.PH California Institute for Regenerative Medicine Esther and Andrew Schorr Patient Advocates Sandra Dillon Cancer Survivor and Stem Cell Champion Catriona Jamieson, M.D., Ph.D. UC San Diego Mehrdad Abedi, M.D. UC Davis Daniela A. Bota, M.D., Ph.D. UC Irvine Sheila Chari, Ph.D. Cell Press Leo D. Wang, M.D., Ph.D. City of Hope National Medical Center Mark Walters, M.D. University of California, San Francisco Thomas Buchanan, M.D. University of Southern California Michael Lewis, M.D. Cedars Sinai Noah Federman, M.D. UCLA Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 39070]…
Experts discuss the immense potential of conducting experiments and manufacturing goods in space. They explore how this could enhance our understanding of health issues, unveil new discoveries, and produce innovative technology for use on Earth. The conversation encompasses collaborations between various industries and scientists, aiming to explore the distinct conditions in space to enhance life for all. Featuring: Catriona Jamieson, M.D., Ph.D. UC San Diego Jana Stoudemire, M.Bio. Axiom Space Alain Berinstain, Ph.D. Space Tango Marc Giulianotti, Ph.D. Sierra Space Kevin Engelbert, M.S.F. NASA Michael Roberts, Ph.D. CASIS Arun Sharma, Ph.D. Cedars Sinai Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39072]…
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1 Using Stem Cells to Model and Treat Human Disease with Clive Svendsen - Sanford Stem Cell Symposium 2023 40:27
Clive Svendsen, Ph.D., leads groundbreaking experiments using stem cell transplants, uncovering unexpected findings. These trials aimed at improving ALS treatments, revealed higher success with upper motor neuron transplants compared to spinal cord methods. Svendsen's exploration of cortical transplants hints at a potential breakthrough. Moreover, his study of stem cell behavior in space opens doors to exciting medical advancements. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39068]…
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Hans Clevers, M.D., Ph.D., shares his research at the intersection of medicine and biology. Clevers discusses revolutionary advances in personalized medicine, where patient-specific treatments can be developed by studying small samples of patients' tissues. He explores the role of specialized cells known as "best for cells" in gastrointestinal health, shedding light on how they may help fight infections. Additionally, he highlights how mini-organs, or organoids, grown in the lab help us understand complex cellular functions and diseases. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39066]…
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1 Regulation of Lung Progenitors in Homeostasis and Injury Repair - Carla Kim Sanford Stem Cell Symposium 2023 29:11
Carla Kim, Ph.D., explains how aging impacts lung cell biology and its potential to reshape our understanding of diseases, including lung cancer. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39254]
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1 Clonal Hematopoiesis in Human Aging and Disease with Siddhartha Jaiswal - Sanford Stem Cell Symposium 2023 28:53
Siddhartha Jaiswal, M.D., Ph.D., discusses clonal hematopoiesis and its impact on aging and diseases. Jaiswal highlights the role of genetic variations, focusing on a specific gene, TET2, and its link to clonal expansion. He explains that certain genetic variations can slow clonal expansion, potentially offering insights into treatments or interventions to mitigate its effects. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39260]…
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Astronaut Peggy Whitson, Ph.D., and Lisa Carnell, Ph.D., discuss various aspects of space exploration, life in microgravity, and the future of space science and research. They delve into the challenges astronauts face, from taste differences in space to innovative 3D printing solutions. The conversation also highlights the importance of stem cell research, personalized medicine, and drug development in space. Whitson's unique perspective offers insights into the awe-inspiring views of Earth from space and the collective responsibility to protect our planet. This thought-provoking discussion exemplifies the intersection of science, space exploration, and the promise of a future beyond our planet. Series: "Stem Cell Channel" [Science] [Show ID: 39073]…
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Ronald DePinho, M.D., explains how telomerase, typically linked to telomere maintenance, serves as a transcriptional co-activator in the brain. Epigenetic repression of TERT, the gene for telomerase, occurs with aging, contributing to aging hallmarks like cellular senescence and inflammation. DePinho's team developed a compound that reactivates TERT, which, when administered to mice, reverses age-related changes. It restores cognitive function, reduces amyloid plaque, and alleviates inflammation. This suggests that maintaining TERT levels can counteract age-related cognitive decline and neurodegeneration, offering potential for treating neurodegenerative diseases like Alzheimer's. DePinho's work expands our understanding of telomerase's multifaceted role in aging and neurodegeneration, holding promise for interventions against these age-related processes. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39071]…
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1 Clonal Expansion of Blood Stem Cells in Aging and Leukemia with Leonard Zon - Sanford Stem Cell Symposium 2023 48:38
Leonard Zon, M.D., discusses cutting-edge research on the intricate relationship between macrophages, stem cells, and the development of leukemia using the zebrafish model. He delves into the fascinating interactions between these cell types, highlighting the role of a "don't eat me" signal and the influence of the leukemic niche. Through cellular barcoding and single-cell RNA sequencing, he unveils a potential therapeutic target which may offer promising insights into treating leukemia by disrupting the stromal activities that support it. Zon showcases the power of zebrafish models in advancing our understanding of hematopoiesis and cancer, promising new avenues for research and treatment. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39064]…
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Stem Cell Channel (Audio)
1 Translating Cell Therapies to Clinical Realities with Malcolm Moos Jr. - Breaking News in Stem Cells 1:20:14
1:20:14 Riproduci in seguito Riproduci in seguito Liste Like Like aggiunto1:20:14
Riproduci in seguito Riproduci in seguito Liste Like Like aggiuntoAre you curious about the future of medical treatments and how they might impact your health? Malcolm Moos, Jr., M.D., Ph.D., shares how cellular therapies are revolutionizing medical treatments. Explore how cells hold the potential to provide new hope for individuals facing various health challenges. Delve into the concept of personalized medicine, discover how regulatory agencies are safeguarding patients' well-being, learn the science behind cell behavior and genetics, and how these processes influence innovative medical treatments and so much more. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 38330]…
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Stem Cell Channel (Audio)
1 Understanding Cell Types in the Developing Human Brain and in Glioblastoma with Aparna Bhaduri - Breaking News in Stem Cells 58:21
Aparna Bhaduri, Ph.D., shares insights into human brain development and its intricate processes. Explore the intriguing reappearance of developmental cell elements in brain cancers like glioblastoma. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 38329]
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Stem Cell Channel (Audio)
1 Induction of Germ Cell Fate from Mammalian Pluripotent Stem Cells with Toshihiro Kobayashi - Breaking News in Stem Cells 57:27
Toshihiro Kobayashi, Ph.D., presents his research on the mechanisms driving cell fate choices in early mammalian embryos. He also discusses the potential application of these principles in future regenerative medicine. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 38328]
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Stem Cell Channel (Audio)
Joseph C. Wu, M.D., Ph.D., shares his pioneering research on cardiovascular disease mechanisms using patient-specific stem cells. Learn about accelerated drug discovery, "clinical trials in a dish," and precision medicine's impact on treatment. Explore genomics, stem cells, imaging, and more. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 38327]…
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Stem Cell Channel (Audio)
1 Spatial Analysis of RNA Distribution During Early Mouse and Human Embryogenesis - Elsy Buitrago-Delgado 54:45
Elsy Buitrago-Delgado, Ph.D., shares how spatial analysis of RNA distribution during early mouse embryogenesis suggests that the first cell fate choice is made at the 4-cell stage. She also discusses how notch signaling regulates cell fate choices during early human development. Series: "Stem Cell Channel" [Science] [Show ID: 38888]…
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Stem Cell Channel (Audio)
1 Genomic Unraveling of Biological and Clinical Heterogeneity in Medulloblastoma - Paul Northcott 1:07:46
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Riproduci in seguito Riproduci in seguito Liste Like Like aggiuntoPaul A. Northcott, Ph.D., St. Jude Children's Research Hospital, shares his work in multi-omic bulk and single-cell approaches to decipher molecular landscapes and developmental origins of medulloblastoma. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 38889]
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Stem Cell Channel (Audio)
1 Stem Cell Approaches to Understanding Acquired and Genetic Epilepsies with Jenny Hsieh - Breaking News in Stem Cells 48:00
Over 65 million people around the globe are affected by epilepsy. Jenny Hsieh's research explores the underlying causes and mechanisms of epilepsies. Using stem cell-based models, including patient-derived neurons, she investigates how genetic and environmental factors contribute to the development of these conditions and potential therapies. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 38326]…
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Stem Cell Channel (Audio)
1 Skeletal Muscle in Three Dimensions: Uncovering Connections Across Development - Matthew A. Romero 50:26
While exercise helps us stay healthy, what is happening on the molecular level? Matthew A. Romero, Ph.D., shares his work to understand how muscle in general and other cells specifically are transcriptionally regulated by exercise and how this affects their general behavior and how this is impacted by diseases such as obesity. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 39033]…
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Stem Cell Channel (Audio)
1 Studying the Brain Through the Lens of Neurodevelopmental Disorders with Gaia Novarino - Breaking News in Stem Cells 1:09:48
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Riproduci in seguito Riproduci in seguito Liste Like Like aggiuntoGaia Navarino shares her work on disorder-causing genetic mutations at the system, cellular and molecular level. With a focus on autism spectrum disorder, she explains techniques used to identify common pathophysiological mechanisms in ASD and how that could provide a framework for the development of effective pharmacological therapies. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 38325]…
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Stem Cell Channel (Audio)
1 Synthetic Human Embryos and Organs with Ali H. Brinvanlou - Breaking News in Stem Cells 1:24:30
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Riproduci in seguito Riproduci in seguito Liste Like Like aggiuntoAli H. Brinvanlou, Ph.D., shares his work using in vitro attached human embryos and genome-edited synthetic embryos derived from human embryonic stem cells to learn the molecular, cellular, and embryological basis of early human development. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 38324]…
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Stem Cell Channel (Audio)
Have questions about publishing in academic journals? Sheila Chari, Ph.D., editor in chief of Cell Stem Cell, explains the process from pre-submission through publication. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 38722]
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Stem Cell Channel (Audio)
1 APOBEC3 Enzymes: From Retroviral Restriction Factors to Cancer Drivers…and Beyond? with Tim Fenton 56:13
Tim Fenton, Ph.D., University of Southampton, shares his work on the roles of APOBEC3 genes. Hear how he is investigating APOBEC regulation and function in keratinocytes. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 38724]
How do visions and norms of scientific progress inform, encourage or constrain democratic governance of science? How do questions of warrant, purpose, and benefit get asked and answered? Andy Murray, Ph.D., sits down with Carrie Wolinetz, Ph.D., National Institutes of Health (NIH), Maria Millan, M.D, California Institute for Regenerative Medicine (CIRM, Derek Thompson, The Atlantic, and Sheila Jasanoff, J.D., Ph.D., Harvard University, to explore these questions and more. Series: "Stem Cell Channel" [Science] [Show ID: 38731]…
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Stem Cell Channel (Audio)
How do we set practical policies that allow scientific discovery to thrive while keeping an eye to risks and benefits for all? Carrie Wolinetz, Ph.D., National Institutes of Health (NIH), looks at current and past policy and shares her insights on the democratic governance of science. Series: "Stem Cell Channel" [Science] [Show ID: 38745]…
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Stem Cell Channel (Audio)
1 Public Good or Commercial Profit: Cosmopolitan Ethics in Public Deliberation 1:26:37
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Riproduci in seguito Riproduci in seguito Liste Like Like aggiuntoHow do structures and practices of privatization and commercialization affect capacities for deliberating and defining limits? How do questions of purpose, desirability, and public good relate to the prioritization of commercialization and profit? What means, formal and informal, exist for setting limits or seeking alignment between public and private interests? Krishanu Saha, Ph.D, Rosemarie Garland-Thomson, Ph.D., Reuven Brandt, Ph.D., and J. Benjamin Hurlbut, Ph.D., engage in a lively discussion of cosmopolitan ethics. Series: "Stem Cell Channel" [Public Affairs] [Humanities] [Show ID: 38730]…
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Stem Cell Channel (Audio)
1 Controversial Case Studies: The Limits of Research in Science 1:28:38
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Riproduci in seguito Riproduci in seguito Liste Like Like aggiuntoHow do research communities contend with controversial science? J. Benjamin Hurlbut, Ph.D., Arizona State University, Alysson Muotri, Ph.D., UC San Diego, Matthew Porteus, M.D., Ph.D., Stanford University, and Jacob (Yaqub) Hanna, M.D., Ph.D., Weizmann Institute of Science, explore controversial case studies and the limitations of scientific deliberation/dissent/ambivalence. Series: "Stem Cell Channel" [Health and Medicine] [Humanities] [Science] [Show ID: 38729]…
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Stem Cell Channel (Audio)
1 Synthetic Ex Utero Embryogenesis: From Naive Pluripotency to Stem-Cell Derived Embryo Models with Jacob Hanna 1:18:24
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Riproduci in seguito Riproduci in seguito Liste Like Like aggiuntoThe identity of somatic and pluripotent cells can be epigenetically reprogrammed and forced to adapt a new functional cell state by different methods and distinct combinations of exogenous factors. The aspiration to utilize such in vitro reprogrammed pluripotent and somatic cells for therapeutic purposes necessitates understanding of the mechanisms of reprogramming and differentiation and elucidating the extent of equivalence of the in vitro derived cells to their in vivo counterparts. Jacob (Yaqub) Hanna, M.D., Ph.D., presents his group’s recent advances toward understanding these fundamental questions and further details ongoing efforts to generate developmentally unrestricted human naive pluripotent cells with embryonic and extra-embryonic developmental potential. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 38323]…
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Stem Cell Channel (Audio)
1 Integrating Single Neurons and Circuits in Stem Cell Derived Neuronal Networks: A Systems Neuroscience Perspective with Julio Martinez-Trujillo - Breaking News in Stem Cells 1:24:28
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Riproduci in seguito Riproduci in seguito Liste Like Like aggiuntoSystems neuroscience aims to understand how brain cells and circuits are organized to produce behavior in living organisms. Julio Martinez-Trujillo, M.D., Ph.D., shares his research studying how neurons interact with one another and other cell types within a circuit during ex vivo and in vivo conditions. He also looks to the future and discusses how stem cell technologies can provide unique access to study human circuits and new insights into the nervous system. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 38322]…
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Stem Cell Channel (Audio)
1 Application of 3D Bioprinting and Biomaterial Technology for Translational Regenerative Medicine with Jin-Hyung Shim - Breaking News in Stem Cells 56:40
As a mechanical engineer, Jin-Hyung Shim, Ph.D. has a unique perspective on tissue and organ regeneration. He discusses the present and potential of 3D printed biomaterials. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 38321]
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Stem Cell Channel (Audio)
1 One Niche to Rule Them All: Stem Cell-Lymphatic Interactome in Regeneration and Cancer with Shiri Gur-Cohen - Sanford Stem Cell Symposium 2022 24:01
Shiri Gur-Cohen, Ph.D., UC San Diego, explains how her lab studies how epithelial stem cells communicate with their vascular microenvironment to advance regeneration and combat metastatic diseases. Series: "Stem Cell Channel" [Education] [Show ID: 38409]
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Stem Cell Channel (Audio)
1 Synthetic Embryology for Building Human Embryo and Organ Models with Jianping Fu - Breaking News in Stem Cells 59:15
How can we better understand the earliest stages of human development? Jianping Fu, Ph.D., University of Michigan, discusses his work using stem cell-derived embryoids. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 38320]
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Stem Cell Channel (Audio)
1 Rescuing Phenotypes in PTHS-Derived Brain Organoids with Alysson Muotri - Sanford Stem Cell Symposium 2022 18:57
Alysson Muotri discusses modeling Pitt-Hopkins syndrome (PTHS) using stem cells and brain organoids. He shares how rescuing TCF4 expression with CRISPR-mediated epigenetic induction of AAV vector delivery provides a gateway for targeted therapeutics for PTHS and related conditions. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 38516]…
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Stem Cell Channel (Audio)
1 Modeling Neurological Conditions Using Stem Cell-Derived Neurons: ApoE and APP in Alzheimer's Disease with Thomas C. Südhof - Sanford Stem Cell Symposium 2022 55:53
Thomas C. Südhof, M.D., Stanford University, discusses facets of the fundamental cell biology of ApoE and APP analyzed in stem cell-derived human neurons. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 38405]
The human placenta may hold important clues to the health of both mothers and babies. Mana Parast, M.D., Ph.D., discusses placental development, what we can learn from pathologic evaluation of the placenta after delivery, and modeling the placenta with stem cells. Karen Mestan, M.S., M.D., shares highlights in neonatal medicine, how to use the placenta as a diagnostic tool to improve the immediate and long term health of newborn patients, and what the role of the placenta could be in NICU management. Catherine and Greg Higgins share their experience as parents with twins in the NICU. Series: "Women in Science" [Health and Medicine] [Show ID: 37969]…
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Stem Cell Channel (Audio)
1 Stem Cell Science and the Genesis of New Therapeutic Strategies for Patients with Derrick Rossi - Sanford Stem Cell Symposium 2022 56:12
Derrick J. Rossi, Ph.D., President and Chief Executive Officer of Convelo Therapeutics has a long history of pioneering methods to make stem cell–based treatments for disease a reality. He shares stories of science making its way from the lab and into biotech with the intention of improving the lives of patients. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 38404]…
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Stem Cell Channel (Audio)
1 iPSC-Derived Brain Cancer Avatars: Lessons Learned and Opportunities for Therapeutic Discovery with Frank Furnari - Sanford Stem Cell Symposium 2022 27:12
Frank Furnari, Ph.D., of UC San Diego, shares his work using stem cells as a vehicle to generate models of brain cancer. Focusing on glioblastoma, he explains how tumor avatars could lead to new therapies. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 38514]
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Stem Cell Channel (Audio)
1 Age- and Mutation Profile-Specific Mechanisms of Pediatric Leukemia Initiation with Jeffrey Magee - Sanford Stem Cell Symposium 2022 28:52
Jeffrey Magee, M.D., Ph.D., of Washington University in St. Louis, discusses how mechanisms that regulate hematopoietic stem cells change with age and how this shapes the biology of pediatric leukemia. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 38398]
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Stem Cell Channel (Audio)
1 Stem Cell Clinical Trials and New Therapies for Patients: Alpha Clinic Director's Panel - Sanford Stem Cell Symposium 2022 58:49
CIRM-funded Alpha Stem Cell Clinics are a network of California medical centers that specialize in delivering stem cell clinical trials to patients. Sandra Dillon shares how their work has impacted treatments for her rare cancer. Maria T. Millan, M.D., Mehrdad Abedi, M.D., Daniela A. Bota, M.D., Ph.D., Sheila Chari, Ph.D., Noah Federman, M.D., Catriona Jamieson, M.D., Ph.D., Sean Turbeville, Ph.D., and Leo D. Wang, M.D., Ph.D., discuss current clinical trials and the future of stem cell research. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 38400]…
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Stem Cell Channel (Audio)
1 Development Renewal and Plasticity in Oral and Gastrointestinal Epithelia with Ophir Klein - Breaking News in Stem Cells 57:34
How do epithelial stem cells enable renewal and regeneration of organs in adults? Ophir Klein, M.D., Ph.D., explains his research in stem cell-fueled tooth renewal and intestinal stem cells. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 38318]
What if we could trick stem cells into thinking they were young again? What would the impact be on human health and aging? Shiri Gur-Cohen, Ph.D., shares her work. Series: "Women in Science" [Health and Medicine] [Show ID: 38216]
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Stem Cell Channel (Audio)
What challenges does aging pose to both individuals and society at large? What causes aging at the cellular and molecular level? Stem cell research is be key to finding solutions that increase our healthspan and change how we think about aging. Robert A.J. Signer, Ph.D., shares what is on the horizon. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 38215]…
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Stem Cell Channel (Audio)
1 Reconstruction of Neural Circuit by Human Neurons with Su-Chun Zhang - Breaking News in Stem Cells 1:15:29
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Riproduci in seguito Riproduci in seguito Liste Like Like aggiuntoSu-Chun Zhang, M.D., Ph.D., shares how neural transplantation cell therapies can be used to treat neurological conditions such as Parkinson's disease. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 38203]
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Stem Cell Channel (Audio)
1 A Closer Look at….Aging 1:19:58
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Riproduci in seguito Riproduci in seguito Liste Like Like aggiuntoWhat challenges does aging pose to individuals and society at large? What causes aging at the cellular and molecular level? What if we could trick stem cells into thinking they were young again? If so, could we leverage stem cells to help live longer, healthier lives? These are just some of the fascinating questions researchers are exploring in today's closer look at the aging process. Robert A.J. Signer, Ph.D., and Shiri Gur-Cohen, Ph.D., examine aging at the molecular and cellular level to show how stem cells may be the key to preventing age-related health problems. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37968]…
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Stem Cell Channel (Audio)
1 Understanding Human Pluripotent Stem Cell States and Their Applications with Thorold Theunissen - Breaking News in Stem Cells 58:10
Thorold Theunissen, Ph.D., of the Washington University School of Medicine in St. Louis shares his work using naive stem cells to model trophoblast development. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37674]
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Stem Cell Channel (Audio)
1 Astrocyte Dysfunction in Autism Spectrum Disorder (ASD) with Dilek Colak - Breaking News in Stem Cells 1:02:55
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Riproduci in seguito Riproduci in seguito Liste Like Like aggiuntoDilek Colak, PhD, shares the results of recent work identifying aberrant Ca2+ signaling in ASD astrocytes as a mechanism that contributes to specific behavioral and neuronal deficits. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37673]
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Stem Cell Channel (Audio)
1 Blastoids: Shaping the Mammalian Embryo for Implantation - Nicolas Rivron: Breaking News in Stem Cells 59:14
Nicolas Rivron, PhD, shares his lab's work to better understand healthy embryo development. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37672]
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Stem Cell Channel (Audio)
1 Epithelial Stem Cells and Combined Cell and Gene Therapy - Breaking News in Stem Cells 1:11:06
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Riproduci in seguito Riproduci in seguito Liste Like Like aggiuntoMichele De Luca, MD, shares his research in gene therapy for epidermolysis bullosa and cell therapy for ocular burns. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37671]
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Stem Cell Channel (Audio)
1 Brain Organoids and Robotics / AI - Sanford Stem Cell Symposium 1:28:38
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Riproduci in seguito Riproduci in seguito Liste Like Like aggiuntoA model of human cortical development could be used to instruct novel computational learning approaches. Alysson Muotri, Phd, Sujeeth Bharadwaj, PhD, Weiwei Yang, and Gabrial Silva, MSc, PhD, discuss the promise, the problems, and the potential when biology and artificial intelligence meet. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37556]…
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Stem Cell Channel (Audio)
Don Cleveland, PhD, shares new research on the role of chromothripsis, targeting cancers driven by ecDNA and more. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37586]
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Stem Cell Channel (Audio)
1 Genomics - Sanford Stem Cell Symposium 1:12:43
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Riproduci in seguito Riproduci in seguito Liste Like Like aggiuntoDan Kaufman, MD, PhD, David Traver, PhD, Gene Yeo, PhD, MBA, discuss the impact of genomics in relation to stell cell research including potential therapeutics for MDS and the role of the somite in hematopoietic stem cell fate. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37561]…
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Stem Cell Channel (Audio)
1 RNA Binding Proteins: A Splicing Story in IPSC Models of MDS with Gene Yeo - Sanford Stem Cell Symposium 26:49
There are at least 2,500 proteins that bind RNA. Gene Yeo, PhD, MBA, explains how his lab studies these RNA binding proteins and their impact on human health. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37589]
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Stem Cell Channel (Audio)
How can electronic medical records be used to improve patient care and outcomes? Epic Systems Judy Faulkner explains how data systems are being used to analyze trends in healthcare, COVID-19 protocols, cancer rates and more. Series: "Stem Cell Channel" [Science] [Show ID: 37563]
How are stem cells being used in regenerative medicine? Adam Engler, PhD, Sharon Gerecht, PhD, Laura Niklason, MD, PhD, and Jordan Miller, PhD, explain the promising research as well as the challenges. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37555]
Erik Viirre, MD, PhD, Christopher Mason, PhD, Jana Stoudemire, and Brinda Rana, MD, discuss how what we learn from space flight could impact terrestrial health as well as the health of future astronauts. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37559]
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Stem Cell Channel (Audio)
1 Drivers of Hematopoietic Stem Cell Aging with Jennifer Trowbridge - Sanford Stem Cell Symposium 30:33
How can we improve the number of years we can live healthy lives? Jennifer Trowbridge, PhD, shares her recent work looking at hematopoietic stem cell aging. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37590]
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Stem Cell Channel (Audio)
1 Decoding the Molecular Cues That Regulate Hematopoietic Stem Cell Specification: Four Roles of the Somite with David Traver - Sanford Stem Cell Symposium 44:09
How are hematopoietic stem cells born during the development of the vertebrate embryo? David Traver, PhD explains his work with zebrafish to understand these processes and the role of the somite in instruction of these cells. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37588]…
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Stem Cell Channel (Audio)
If we can build living tissue whose form is patterned off natural organs, will it have the same function? Jordan Miller, PhD discusses the design space of engineered living tissues and the challenges presented. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37581]
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Stem Cell Channel (Audio)
1 How Ebola Informs the Fight Against COVID-19 - Antibodies Against SARS-CoV-2: A Global Collaboration - Breaking News in Stem Cells 58:35
Using a global collaboration established to find antibodies to fight Ebola, scientists have joined together to discover treatments for COVID-19. Erica Ollmann Saphire, Phd, of the La Jolla Institute for Immunology, shares how this collaboration, known as CoVIC, furthers science and public health while creating a template for rapid discovery. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37669]…
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Stem Cell Channel (Audio)
Sharon Gerecht, PhD, explains how the microenvironment regulates vascular fate in assembly. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37579]
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Stem Cell Channel (Audio)
What are the obstacles that stand between us and engineering functional lungs? Laura Niklason, MD, PhD outline the promises and challenges of lung regeneration. She details current studies that may unveil a roadmap for building functional lung aveolus. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37580]…
Alpha Stem Cell Clinics is a network of clinics providing stem cell clinical trials to patients. Directors of these clinics throughout the state of California share what the future of these trials looks like, what the future holds for alpha clinics, funding for research, and patient impacts. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37560]…
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Stem Cell Channel (Audio)
1 Defining Regeneration and Non-Regeneration at a Cellular and Molecular Level - Breaking News in Stem Cells 55:55
Elly Tanaka of the Research Institute of Molecular Pathology (IMP), Vienna Biocenter shares her work defining what it means to have successful regeneration and studying examples of lack of regeneration and what that means at the cellular and molecular levels. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37019]…
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Stem Cell Channel (Audio)
1 Neuro-archealization: Resurrecting Genetic Variations in Human Brain Organoids - Breaking News in Stem Cells 52:20
Understanding the evolutionary path and the tradeoffs of the modern human brain will likely illuminate the origins of human disease. Alysson Muotri explains his research using stem cells to model Neanderthal brains in an effort to better understand our origins as well as our future. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37018]…
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Stem Cell Channel (Audio)
1 The Immune System in Regenerative Medicine: Friend or Foe To Stem Cells? - Breaking News in Stem Cells 57:09
Dr. Elisseeff is a leading expert in the field of tissue engineering. She directs the Translational Tissue Engineering Center where she and her team of scientists study stem cells, develop new biomaterials, and design new technologies for regenerative medicine. The goal of her lab is to engineer technologies to repair lost tissues. Specifically, Elisseeff's lab examines hydrogels as a scaffold for tissue engineering. Hydrogels are ideal due to their high water content for nutrient and waste transport, and their ability to encapsulate cells and to implant in a minimally invasive manner. The lab is currently focused on developing synthetic-biological hydrogels with highly controlled physical properties and biological function. The discovery of human embryonic stem cells has created the possibility to regenerate any tissue from a single, totipotent cell population. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Education] [Show ID: 37017]…
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Stem Cell Channel (Audio)
1 A Closer Look at…Cancer Prevention 1:26:39
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Riproduci in seguito Riproduci in seguito Liste Like Like aggiuntoScott Lippman, MD, Ludmil Alexandrov, PhD, and Hannah Carter, PhD discuss the genetic, lifestyle-related, and environmental risk factors identified in cancer prevention. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 37281]
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1 From COVID-19 to Heart Regeneration: The Pluripotent Uses of Human Stem Cells with Chuck Murry - Breaking News in Stem Cells 1:00:39
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Riproduci in seguito Riproduci in seguito Liste Like Like aggiuntoChuck Murry, MD, PhD shares recent research on using cardiomyocytes to model COVID-19 heart disease. He also discusses current efforts to regenerate the heart and reduce arrhythmias. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37016]
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1 Normal and Malignant Stem Cells: New Opportunities and New Complexities with Connie Eaves - Breaking News in Stem Cells 1:13:40
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Riproduci in seguito Riproduci in seguito Liste Like Like aggiuntoConnie Eaves, PhD presents her research and examines this moment in time in stem cell biology. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37015]
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1 Bioengineering Early CNS Morphogenesis for a Scalable Neural Tube Defect Risk and Developmental Neurotoxicity Assay with Randolph Ashton 1:04:38
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Riproduci in seguito Riproduci in seguito Liste Like Like aggiuntoRandolph Ashton, PhD discusses novel tissue engineering methodologies to derive brain and spinal cord tissues from human pluripotent stem cells, which can be used to create groundbreaking regenerative therapies and models of neurological disorders. Series: "Stem Cell Channel" [Science] [Show ID: 37014]…
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1 A Closer Look at...Spinal Cord Injury 1:20:31
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Riproduci in seguito Riproduci in seguito Liste Like Like aggiuntoMark Tuszynski, MD, Ph.D., Bob Yant, and Lawrence S.B. Goldstein, Ph.D. discuss the newest research and treatments for spinal cord injury, including how neural stem cells may be leveraged to potentially regain function. Series: "Stem Cell Channel" [Health and Medicine] [Science] [Show ID: 37102]
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Stem Cell Channel (Audio)
Karen Christman and Marianna Alperin discuss the newest discoveries and cutting-edge techniques for pro-regenerative biomaterials for heart and skeletal muscle with applications to cardiovascular disease and pelvic floor disorders. Series: "Women in Science" [Health and Medicine] [Science] [Show ID: 36848]…
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Stem Cell Channel (Audio)
1 A Closer Look at...COVID-19 1:37:40
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Riproduci in seguito Riproduci in seguito Liste Like Like aggiuntoDavey Smith, MD, Sheldon Morris MD, MPH, and Robert "Chip" Schooley, MD discuss the newest research on COVID-19 including the lessons that can be learned, antivirals, and how to interpret the data. Series: "Stem Cell Channel" [Health and Medicine] [Show ID: 37068]
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Stem Cell Channel (Audio)
1 Capturing Multiple CNS Cell Types and Genotypes in Human Stem Cell-Based Models of Neural Disease with Lorenz Studer 1:02:30
1:02:30 Riproduci in seguito Riproduci in seguito Liste Like Like aggiunto1:02:30
Riproduci in seguito Riproduci in seguito Liste Like Like aggiuntoLorenz Studer, MD. Director, Center for Stem Cell Biology, Sloan Kettering Institute, presents his research. The Studer laboratory investigates human stem cells as tools to understand normal and pathological development in the nervous system and to develop cell-based strategies for regenerative medicine. Series: "Autism Programs for Medical Professionals" [Health and Medicine] [Science] [Show ID: 37009]…
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Simile a Stem Cell Channel (Audio)
The BMJ brings you interviews with the people who are shaping medicine and science around the world.
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Flash Forward is a show about possible (and not so possible) future scenarios. What would the warranty on a sex robot look like? How would diplomacy work if we couldn’t lie? Could there ever be a fecal transplant black market? (Complicated, it wouldn’t, and yes, respectively, in case you’re curious.) Hosted and produced by award winning science journalist Rose Eveleth, each episode combines audio drama and journalism to go deep on potential tomorrows, and uncovers what those futures might re ...
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As She Rises brings together local poets and activists from throughout North America to depict the effects of climate change on their home and their people. Each episode carries the listener to a new place through a collection of voices, local recordings and soundscapes. Stories span from the Louisiana Bayou, to the tundras of Alaska to the drying bed of the Colorado River. Centering the voices of native women and women of color, As She Rises personalizes the elusive magnitude of climate cha ...
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Concise summaries of everything published in the latest weekly issue of the New England Journal of Medicine (NEJM). NEJM publishes new medical research findings, review articles, and editorial opinion on topics of importance to biomedical science and clinical practice.
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Come dive into one of the curiously delightful conversations overheard at National Geographic’s headquarters, as we follow explorers, photographers, and scientists to the edges of our big, weird, beautiful world. Hosted by Peter Gwin and Amy Briggs.
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This Week in Evolution is a podcast on the biology of what makes us tick. Hosts Nels Elde and Vincent Racaniello take you through the new evolution that has been revolutionized by the field of genomics and molecular biology.
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Read along with the Sword and Laser book club! From classic science fiction to the latest gritty fantasy, we cover it. Subscribe for book discussions, author interviews, hot releases, and news from the genre fiction world!
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Discussions about the science of nutrition, dietetics and health. The podcast that educates through nuanced conversations, exploring evidence and cultivating critical thinking. Hosted by Danny Lennon.
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Science Friction's latest series is: Cooked. We dig into food science pickles. Why are studies showing that ice cream could be good for you? Do we really need as many electrolytes as the internet says? And why are people feeling good on the carnivore diet? Nutrition and food scientist Dr Emma Beckett takes us through what the evidence says about foods like meat, ice cream and potatoes — and unpicks why nutrition studies can be so conflicting and confusing. All six episodes of Cooked are avai ...
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Going Wild with Dr. Rae Wynn Grant is a different kind of nature show about the human drama of saving animals. From a paleoanthropologist who hunts fossils in conflict zones to someone who helped save an endangered species while in prison, in season four we will hear from real-life heroes and nature advocates with widely different expertise and life experiences that led them to be champions for the natural world. Wildlife biologist and host Dr. Rae Wynn-Grant has been studying wild animals i ...
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