How can we, humans, look at our relationship to nature differently? In season three of Going Wild, on top of stories about animals, we invite you to journey through the entire ecological web — from the tiniest of life forms to apex predators — alongside the scientists, activists and adventurers who study it. Wildlife biologist and host Dr. Rae Wynn-Grant has been studying wild animals in their natural habitats all over the world for years. Our award-winning podcast takes you inside the hidde ...
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EP 107: Integrating Genomics and Individualised Medicine into the Mayo Clinic Healthcare System with Dr. Konstantinos Lazaridis
Manage episode 376935968 series 2631947
Contenuto fornito da Sano Genetics. Tutti i contenuti dei podcast, inclusi episodi, grafica e descrizioni dei podcast, vengono caricati e forniti direttamente da Sano Genetics o dal partner della piattaforma podcast. Se ritieni che qualcuno stia utilizzando la tua opera protetta da copyright senza la tua autorizzazione, puoi seguire la procedura descritta qui https://it.player.fm/legal.
In this episode of The Genetics Podcast, we welcome Dr. Konstantinos Lazaridis, the Executive Director of the Center for Individualized Medicine at the Mayo Clinic. Tune in to learn about the impacts of genomics and individualised medicine on rare liver diseases and advanced cancers . Discover how the Mayo Clinic actively uses genomic testing, precision medicine, and environmental interventions to improve patient outcomes.
Timestamps:
0:00 Introduction
0:00 Introduction
0:32 Insights into the Center for Individualised Medicine at the Mayo Clinic, including the importance of predictive genomics, research in rare and undiagnosed diseases, and the integration of genomics into healthcare
4:40 Mayo Clinic’s Program for Rare and Undiagnosed Diseases (PRaUD): challenges faced and lessons learned
8:28 The Tapestry Study: integrating genomic data into patient care plans
11:40 The Tapestry Study: challenges in implementing healthcare interventions based on genetic findings
12:10 The Tapestry Study: The path to 100,000 whole exome sequences, including exciting findings, novel diagnoses, and future projections
13:20 The impact of the exposome (environmental exposures over the course of a lifetime) on genetic risk
16:45 Untapped data sources in exposome research
18:50 Linking the exposome to direct changes in cell physiology and metabolic pathways
21:34 Sources of exposome data - from blood draws to tissue samples
22:05 Painting a picture of the Center for Individualized Medicine in 20 years
23:30 Enhancing disease prevention, particularly for germline genetic diseases
26:38 Two scientists’ views on the humbling nature of biology
27:00 Mayo Clinic’s efforts to share its findings and precision medicine model with the world
28:10 Closing Remarks
187 episodi
Manage episode 376935968 series 2631947
Contenuto fornito da Sano Genetics. Tutti i contenuti dei podcast, inclusi episodi, grafica e descrizioni dei podcast, vengono caricati e forniti direttamente da Sano Genetics o dal partner della piattaforma podcast. Se ritieni che qualcuno stia utilizzando la tua opera protetta da copyright senza la tua autorizzazione, puoi seguire la procedura descritta qui https://it.player.fm/legal.
In this episode of The Genetics Podcast, we welcome Dr. Konstantinos Lazaridis, the Executive Director of the Center for Individualized Medicine at the Mayo Clinic. Tune in to learn about the impacts of genomics and individualised medicine on rare liver diseases and advanced cancers . Discover how the Mayo Clinic actively uses genomic testing, precision medicine, and environmental interventions to improve patient outcomes.
Timestamps:
0:00 Introduction
0:00 Introduction
0:32 Insights into the Center for Individualised Medicine at the Mayo Clinic, including the importance of predictive genomics, research in rare and undiagnosed diseases, and the integration of genomics into healthcare
4:40 Mayo Clinic’s Program for Rare and Undiagnosed Diseases (PRaUD): challenges faced and lessons learned
8:28 The Tapestry Study: integrating genomic data into patient care plans
11:40 The Tapestry Study: challenges in implementing healthcare interventions based on genetic findings
12:10 The Tapestry Study: The path to 100,000 whole exome sequences, including exciting findings, novel diagnoses, and future projections
13:20 The impact of the exposome (environmental exposures over the course of a lifetime) on genetic risk
16:45 Untapped data sources in exposome research
18:50 Linking the exposome to direct changes in cell physiology and metabolic pathways
21:34 Sources of exposome data - from blood draws to tissue samples
22:05 Painting a picture of the Center for Individualized Medicine in 20 years
23:30 Enhancing disease prevention, particularly for germline genetic diseases
26:38 Two scientists’ views on the humbling nature of biology
27:00 Mayo Clinic’s efforts to share its findings and precision medicine model with the world
28:10 Closing Remarks
187 episodi
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