This Week in Evolution is a podcast on the biology of what makes us tick. Hosts Nels Elde and Vincent Racaniello take you through the new evolution that has been revolutionized by the field of genomics and molecular biology.
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Player FM - Internet Radio Done Right
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Contenuto fornito da Jon Chee. Tutti i contenuti dei podcast, inclusi episodi, grafica e descrizioni dei podcast, vengono caricati e forniti direttamente da Jon Chee o dal partner della piattaforma podcast. Se ritieni che qualcuno stia utilizzando la tua opera protetta da copyright senza la tua autorizzazione, puoi seguire la procedura descritta qui https://it.player.fm/legal.
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Flash Forward is a show about possible (and not so possible) future scenarios. What would the warranty on a sex robot look like? How would diplomacy work if we couldn’t lie? Could there ever be a fecal transplant black market? (Complicated, it wouldn’t, and yes, respectively, in case you’re curious.) Hosted and produced by award winning science journalist Rose Eveleth, each episode combines audio drama and journalism to go deep on potential tomorrows, and uncovers what those futures might re ...
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Going Wild with Dr. Rae Wynn Grant is a different kind of nature show about the human drama of saving animals. From a paleoanthropologist who hunts fossils in conflict zones to someone who helped save an endangered species while in prison, in season four we will hear from real-life heroes and nature advocates with widely different expertise and life experiences that led them to be champions for the natural world. Wildlife biologist and host Dr. Rae Wynn-Grant has been studying wild animals i ...
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Every Day Is Saturday Podcast For Motivation, Inspiration And Success
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This Week in Microbiology is a podcast about unseen life on Earth hosted by Vincent Racaniello and friends. Following in the path of his successful shows 'This Week in Virology' (TWiV) and 'This Week in Parasitism' (TWiP), Racaniello and guests produce an informal yet informative conversation about microbes which is accessible to everyone, no matter what their science background.
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For many travelers, Antarctica is a bucket-list destination, a once-in-a-lifetime opportunity to touch all seven continents. In 2023, a record-breaking 100,000 tourists made the trip. But the journey begs a fundamental question: What do we risk by traveling to a place that is supposed to be uninhabited by humans? And as the climate warms, should we really be going to Antarctica in the first place? SHOW NOTES: Kara Weller: The Impossible Dilemma of a Polar Guide Marilyn Raphael: A twenty-first century structural change in Antarctica’s sea ice system Karl Watson: First Time in Antarctica Jeb Brooks : 7 Days in Antarctica (Journey to the South Pole) Metallica - Freeze 'Em All: Live in Antarctica Learn about your ad choices: dovetail.prx.org/ad-choices…
🧬 Nathan Clark - Ganymede - Part 4 | Data Integration & Automation in the Life Sciences | Building a Technical Team & Go-To-Market Motion | Creating Efficient Data Infrastructures | Automating Complex Workflows
Manage episode 430699942 series 3461709
Contenuto fornito da Jon Chee. Tutti i contenuti dei podcast, inclusi episodi, grafica e descrizioni dei podcast, vengono caricati e forniti direttamente da Jon Chee o dal partner della piattaforma podcast. Se ritieni che qualcuno stia utilizzando la tua opera protetta da copyright senza la tua autorizzazione, puoi seguire la procedura descritta qui https://it.player.fm/legal.
As a podcast listener, you can redeem exclusive discounts with a growing list of biotech vendors and get $500 off your first equipment lease by using promo code “TBSP” on https://www.excedr.com/rewards.
Part 4 of 4.
Part 4 of 4.
My guest for this week’s episode is Nathan Clark, Founder and CEO of Ganymede. Ganymede is the modern cloud data platform for the life sciences and manufacturing. Their Lab-as-Code technology allows you to quickly integrate and harmonize lab instruments and app data, automate analysis, visualize all your data in dashboards built over a powerful data lake, and ultimately speed up your operations to accelerate science or production.
Prior to founding Ganymede, Nathan was Product Manager for several of Benchling's data products, including the Insights BI tool and Machine Learning team. Before Benchling, Nathan worked at Affirm as a Senior Product Manager and was also a Trader at Goldman Sachs.
Join us this week and hear about:
- Nathan’s experience with data integration and automation in the life sciences and building a product for bioinformatics engineers and data scientists
- His experience building the technical team and creating a go-to-market motion
- His vision for Ganymede in the years to come
- The challenges biotech companies face managing and analyzing large amounts of data
- The importance of streamlining processes through automation and data integration
Nathan’s extensive background in machine learning and data systems across financial and lab technology and knowledge of their applications in the life sciences offers unique insights for founders to benefit from. Please enjoy my conversation with Nathan Clark.
Timestamps:
00:28 Intro
01:56 Empowering bioinformatics engineers with data integration and automation
04:38 The vision for Ganymede’s developer platform; automating wet lab data
06:39 The key to Ganymede’s quick growth: faster integrations
08:18 Nathan’s go-to-market motion at Ganymede; explaining your product
10:29 Which companies benefit the most from Ganymede?
14:23 Data strategies, modern data stacks, and building a data lake
20:21 Future vision for Ganymede; expanding platform features and reducing bugging cycles 27:02 Automating complex workflows to unlock the next level of R&D
29:40 Shout-outs and advice for 21-year old self
33:29 Outro
Find Our Guest, Nathan Clark, at these links:
Find Our Host, Jon Chee, at these links:
Social & Website
LinkedIn: https://www.linkedin.com/company/excedr/
Youtube: https://www.youtube.com/@excedr
Instagram: https://www.instagram.com/excedr_inc
Twitter: https://twitter.com/ExcedrInc
Facebook: https://www.facebook.com/excedr
TikTok: https://www.tiktok.com/@excedr
Podcast Website: https://www.thebiotechstartupspodcast.com/
Enriched Notes:
Topics Mentioned:
Ganymede https://www.ganymede.bio/
Ganymede Products https://www.ganymede.bio/products
Salesforce https://www.salesforce.com/
Hubspot https://www.hubspot.com/
Ramp https://ramp.com/
Benchling https://www.benchling.com/
Data Science & Analysis https://aws.amazon.com/what-is/data-science/
Bioinformatics https://www.genome.gov/genetics-glossary/Bioinformatics
Automating Wet Lab Data https://blog.ganymede.bio/4-data-first-strategies-for-lab-automation/
Data Lakes & the Modern Data Stack https://blog.ganymede.bio/the-essential-lab-data-tech-stack-for-every-stage-of-drug-development/
People Mentioned:
Nicholas (Nicky) Ksiezopolski https://www.linkedin.com/in/nksiezopolski/
Sanjay Saraf https://www.linkedin.com/in/sanjaysaraf/
The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.
139 episodi
CondividiManage episode 430699942 series 3461709
Contenuto fornito da Jon Chee. Tutti i contenuti dei podcast, inclusi episodi, grafica e descrizioni dei podcast, vengono caricati e forniti direttamente da Jon Chee o dal partner della piattaforma podcast. Se ritieni che qualcuno stia utilizzando la tua opera protetta da copyright senza la tua autorizzazione, puoi seguire la procedura descritta qui https://it.player.fm/legal.
As a podcast listener, you can redeem exclusive discounts with a growing list of biotech vendors and get $500 off your first equipment lease by using promo code “TBSP” on https://www.excedr.com/rewards.
Part 4 of 4.
Part 4 of 4.
My guest for this week’s episode is Nathan Clark, Founder and CEO of Ganymede. Ganymede is the modern cloud data platform for the life sciences and manufacturing. Their Lab-as-Code technology allows you to quickly integrate and harmonize lab instruments and app data, automate analysis, visualize all your data in dashboards built over a powerful data lake, and ultimately speed up your operations to accelerate science or production.
Prior to founding Ganymede, Nathan was Product Manager for several of Benchling's data products, including the Insights BI tool and Machine Learning team. Before Benchling, Nathan worked at Affirm as a Senior Product Manager and was also a Trader at Goldman Sachs.
Join us this week and hear about:
- Nathan’s experience with data integration and automation in the life sciences and building a product for bioinformatics engineers and data scientists
- His experience building the technical team and creating a go-to-market motion
- His vision for Ganymede in the years to come
- The challenges biotech companies face managing and analyzing large amounts of data
- The importance of streamlining processes through automation and data integration
Nathan’s extensive background in machine learning and data systems across financial and lab technology and knowledge of their applications in the life sciences offers unique insights for founders to benefit from. Please enjoy my conversation with Nathan Clark.
Timestamps:
00:28 Intro
01:56 Empowering bioinformatics engineers with data integration and automation
04:38 The vision for Ganymede’s developer platform; automating wet lab data
06:39 The key to Ganymede’s quick growth: faster integrations
08:18 Nathan’s go-to-market motion at Ganymede; explaining your product
10:29 Which companies benefit the most from Ganymede?
14:23 Data strategies, modern data stacks, and building a data lake
20:21 Future vision for Ganymede; expanding platform features and reducing bugging cycles 27:02 Automating complex workflows to unlock the next level of R&D
29:40 Shout-outs and advice for 21-year old self
33:29 Outro
Find Our Guest, Nathan Clark, at these links:
Find Our Host, Jon Chee, at these links:
Social & Website
LinkedIn: https://www.linkedin.com/company/excedr/
Youtube: https://www.youtube.com/@excedr
Instagram: https://www.instagram.com/excedr_inc
Twitter: https://twitter.com/ExcedrInc
Facebook: https://www.facebook.com/excedr
TikTok: https://www.tiktok.com/@excedr
Podcast Website: https://www.thebiotechstartupspodcast.com/
Enriched Notes:
Topics Mentioned:
Ganymede https://www.ganymede.bio/
Ganymede Products https://www.ganymede.bio/products
Salesforce https://www.salesforce.com/
Hubspot https://www.hubspot.com/
Ramp https://ramp.com/
Benchling https://www.benchling.com/
Data Science & Analysis https://aws.amazon.com/what-is/data-science/
Bioinformatics https://www.genome.gov/genetics-glossary/Bioinformatics
Automating Wet Lab Data https://blog.ganymede.bio/4-data-first-strategies-for-lab-automation/
Data Lakes & the Modern Data Stack https://blog.ganymede.bio/the-essential-lab-data-tech-stack-for-every-stage-of-drug-development/
People Mentioned:
Nicholas (Nicky) Ksiezopolski https://www.linkedin.com/in/nksiezopolski/
Sanjay Saraf https://www.linkedin.com/in/sanjaysaraf/
The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.
139 episodi
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🧬 The Biotech Startups Podcast is powered by Excedr —helping life science startups accelerate R&D and commercialization with founder-friendly equipment leasing. Skip the upfront costs, stay lean, and focus on breakthrough science. As a TBSP listener, you can get exclusive perks through Excedr’s partner network—special savings, promotions, and more. Explore these offers today: https://www.excedr.com/partners . "You have to be curious. You have to enjoy the problems as opposed to view them as problems. You can view them as puzzle pieces that you get to put together, which is a lot of fun." In this episode of The Biotech Startups Podcast, Rabia Khan shares the pivotal experiences that shaped her approach to biotech innovation, from her time at BenevolentAI and Sensyne Health to building and leading high-performance teams at the intersection of biology, machine learning, and clinical data. Rabia discusses the challenges of aligning scientists and engineers around a shared language, the importance of integrating platform and program development, and the cultural shifts needed to drive real innovation in drug discovery. She also reflects on the value of curiosity, risk-taking, and the lessons learned from managing major pharma partnerships and scaling teams under intense pressure. Key topics covered: Bridging Biology & Machine Learning: Breaking barriers to spark drug discovery innovation. Platform vs. Program Development: Integrate or stagnate—unite teams to win in biotech. Building & Leading Teams: Scaling fast and thriving in high-stakes pharma. The Power of Curiosity & Risk-Taking: Question, risk, and grow—breakthroughs follow. Sales & Resilience in Biotech: Master selling and stay tough to succeed in science. If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening. Subscribe to the Podcast: Apple: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Spotify: https://open.spotify.com/show/2PSL162R2s0zOwU5913Zv4 Youtube: https://www.youtube.com/@thebiotechstartupspodcast Website: https://www.thebiotechstartupspodcast.com/ Find our guest, Rabia Khan, at these links: LinkedIn: https://www.linkedin.com/in/rabiatkhan/ Website: https://www.serna.bio/ Find our host, Jon Chee, at these links: LinkedIn: https://www.linkedin.com/in/jonchee Learn more about Excedr: LinkedIn: https://www.linkedin.com/company/excedr/ Website: https://www.excedr.com Intro & Outro Songs Created by OkKyojin, Owned by Excedr: Website: https://flow.page/kyojin Resources & Articles: ICD-10 Codes and the Classification of Disease: https://icd.who.int/browse10/2019/en HubSpot CEO on 20VC: https://podcasts.apple.com/gb/podcast/20vc-hubspot-ceo-on-where-value-accrues-in-saas-ai/id958230465?i=1000699464274 The Economist’s Approach to Business Clarity and Value Creation: https://businesslibrary.uflib.ufl.edu/economicsbooks Companies, Universities, & People mentioned: BenevolentAI: https://www.benevolent.com/ Sensyne Health: https://www.sensynehealth.com/ Serna Bio: https://www.serna.bio/ Steven Hamblin: https://www.linkedin.com/in/stevenrhamblin/?originalSubdomain=uk Kate Yen, Ph.D.: https://www.linkedin.com/in/kate-yen-448b22108/ Timestamps: 00:00 Intro 02:04 The Importance of Shared Language Across Disciplines 03:02 Platform vs. Program Development in Biotech 06:02 The Platform-Program Dichotomy and Capital Market Perspectives 07:29 Aligning Machine Learning Engineers and Biologists 09:30 Changing the Culture of Biology to Embrace Engineering Practices 11:07 The Role of Curiosity and Naivety in Innovation 12:18 Starting a Company: Risk-Taking and Support Systems 17:11 Transition from BenevolentAI to Sensyne Health 22:16 Challenges of Working with Clinical Data and ICD-10 Codes 25:17 Building and Scaling a Machine Learning Team at Sensyne Health 31:03 Leadership, Mentorship, and Hiring for Growth 33:14 The Underrated Power of Sales Skills in Biotech 36:57 Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…
1 🧬 Rabia Khan - Serna Bio: Bridging Science & Tech—PhDs, MBAs, & Biotech Innovation (Part 2/4) 45:29
🧬 The Biotech Startups Podcast is powered by Excedr —helping life science startups accelerate R&D and commercialization with founder-friendly equipment leasing. Skip the upfront costs, stay lean, and focus on breakthrough science. As a TBSP listener, you can get exclusive perks through Excedr’s partner network—special savings, promotions, and more. Explore these offers today: https://www.excedr.com/partners . “I wish someone had told me when I was starting my PhD to sit down and say, ‘what do I want out of this?’ and [then] write it down. Because, unlike the UK, where PhDs are three years and time bound, in Canada, they are neither time bound nor three years. And so you can meander." In this episode of The Biotech Startups Podcast, Rabia Khan, founder and CEO of Serna Bio , joins host Jon Chee to reflect on her unconventional journey through academia, business, and biotech innovation. Rabia shares how her curiosity, resilience, and embracing uncertainty shaped her journey through a PhD in genetics and an MBA. She discusses the emotional challenges of working with animal models, the benefits and limits of business school for scientists, and personal struggles, including her father’s illness. She recounts early setbacks, like rejected consulting jobs, and how a cold email landed her at Meta (now part of Chan Zuckerberg Biohub). Rabia emphasizes “manufacturing serendipity,” differences between founder and employee mindsets, and lessons from her work at BenevolentAI, highlighting the importance of cross-disciplinary communication and challenging industry norms. Key topics covered: PhD Realities: Tackling emotional and practical research challenges Dual-Degree Insights: Balancing PhD and MBA, knowing business limits Personal Adversity: Turning family illness into resilience Career Breakthroughs: Creating and seizing biotech startup chances Bridging Disciplines: Fusing biology and ML to expand drug targets If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening. Subscribe to the Podcast: Apple: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Spotify: https://open.spotify.com/show/2PSL162R2s0zOwU5913Zv4 Youtube: https://www.youtube.com/@thebiotechstartupspodcast Website: https://www.thebiotechstartupspodcast.com/ Find our guest, Rabia Khan, at these links: LinkedIn: https://www.linkedin.com/in/rabiatkhan/ Website: https://www.serna.bio/ Find our host, Jon Chee, at these links: LinkedIn: https://www.linkedin.com/in/jonchee Learn more about Excedr: LinkedIn: https://www.linkedin.com/company/excedr/ Website: https://www.excedr.com Intro & Outro Songs Created by OkKyojin, Owned by Excedr: Website: https://flow.page/kyojin Resources & Articles: Case in Point (book): https://caseinterview.com/case-in-point SWOT Analysis: https://en.wikipedia.org/wiki/SWOT_analysis CRISPR Technology: https://www.genome.gov/genetics-glossary/CRISPR iPSC (Induced Pluripotent Stem Cells): https://en.wikipedia.org/wiki/Induced_pluripotent_stem_cell GWAS (Genome-Wide Association Studies): https://www.nature.com/articles/s43586-021-00056-9 Ensembl: https://www.ensembl.org/index.html The concept of the “druggable genome”: https://www.frontiersin.org/journals/bioinformatics/articles/10.3389/fbinf.2022.958378/full Companies, Universities, & People mentioned: Francis Crick Institute: https://www.crick.ac.uk/ BenevolentAI: https://www.benevolent.com/ Meta (Acquired by Chan Zuckerberg Biohub): https://techcrunch.com/2017/01/23/chan-zuckerberg-initiative-meta/ GSK (GlaxoSmithKline): https://www.gsk.com/ Thermo Fisher Scientific: https://www.thermofisher.com/ Sensyne Health: https://www.sensyne.com/ Sam Molyneux: https://www.linkedin.com/in/sammolyneux Amy Molyneux: https://www.linkedin.com/in/amymolyneux/ Jackie Hunter: https://www.linkedin.com/in/drjackiehunter/ Timestamps: 00:00 Intro 00:49 Rabia’s PhD Experience and Challenges 06:07 Comparing PhD Systems in Canada vs. UK 08:21 MBA Insights and Frameworks 14:28 Personal Adversity and Career Impact 17:05 Coping with Family Illness and Career Decisions 21:26 First Job at Meta and Serendipity 30:00 Postdoc at Francis Crick Institute 35:10 Joining BenevolentAI and Early Experiences 39:24 Challenges in Drug Discovery and Druggable Genome 43:41 Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…
🧬 The Biotech Startups Podcast is powered by Excedr —helping life science startups accelerate R&D and commercialization with founder-friendly equipment leasing. Skip the upfront costs, stay lean, and focus on breakthrough science. As a TBSP listener, you can get exclusive perks through Excedr’s partner network—special savings, promotions, and more. Explore these offers today: https://www.excedr.com/partners . "I was born and raised in a developing country. I was born and raised in Pakistan. And it's very interesting when you're born in a developing country. That's your world. Right? That's all you know." In this episode of The Biotech Startups Podcast, we delve into Rabia Khan's remarkable journey from her childhood in Pakistan to founding Serna Bio, an AI-enabled drug discovery company. Rabia shares how her early experiences in a developing country, her aunt's battle with schizophrenia, and the sequencing of the human genome in 2000 sparked her passion for genetics and healthcare. She recounts how her career options were either medicine or engineering, setting her on a path that would eventually lead to pioneering work at the intersection of AI and biotechnology. Rabia describes her transition to McGill University in Montreal, facing the shock of -40°C weather with only a leather jacket while navigating life as an international student with no support system. Despite these challenges, she pursued dual interests in biology and economics, finding her first research opportunity in a schizophrenia lab where she started by pipetting water and washing dishes. Key topics covered: Formative Influences: Shaped by Pakistan upbringing, aunt's schizophrenia, and genome sequencing Educational Journey: Balancing biology and economics at McGill First Research Experiences: From lab basics to discovering a disease-causing gene Decision-Making Frameworks: Applying economics principles to business decisions Family Influence: Mother's practicality and father's entrepreneurial drive guided her path If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening. Subscribe to the Podcast: Apple: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Spotify: https://open.spotify.com/show/2PSL162R2s0zOwU5913Zv4 Youtube: https://www.youtube.com/@thebiotechstartupspodcast Website: https://www.thebiotechstartupspodcast.com/ Find our guest, Rabia Khan, at these links: LinkedIn: https://www.linkedin.com/in/rabiatkhan/ Website: https://www.serna.bio/ Find our host, Jon Chee, at these links: LinkedIn: https://www.linkedin.com/in/jonchee Learn more about Excedr: LinkedIn: https://www.linkedin.com/company/excedr/ Website: https://www.excedr.com Intro & Outro Songs Created by OkKyojin, Owned by Excedr: Website: https://flow.page/kyojin Resources & Articles: The Human Genome Project https://www.genome.gov/human-genome-project Schizophrenia https://en.wikipedia.org/wiki/Schizophrenia Opportunity Cost https://www.investopedia.com/terms/o/opportunitycost.asp Marginal Utility https://www.investopedia.com/terms/m/marginalutility.asp The Prisoner's Dilemma https://en.wikipedia.org/wiki/Prisoner%27s_dilemma Ray Dalio's Decision Making Frameworks https://www.principles.com/principles/7df5502f-46e5-47d5-8fd7-8fc70843b726/ Nassim Taleb's Antifragility https://en.wikipedia.org/wiki/Antifragile_(book) Black Swan by Nassim Taleb https://en.wikipedia.org/wiki/The_Black_Swan:_The_Impact_of_the_Highly_Improbable McGill University's Human Genetics Program https://www.mcgill.ca/humangenetics/our-programs/program-information Hydatidiform Moles Research https://www.ncbi.nlm.nih.gov/books/NBK459155/ Companies, Universities, & People mentioned: Benevolent AI: https://www.benevolent.com/ Meta: https://techcrunch.com/2017/01/23/chan-zuckerberg-initiative-meta/ Bayer: https://www.bayer.com/ BMS (Bristol Myers Squibb): https://www.bms.com/ Roche: https://www.roche.com/ Alexion: https://www.alexion.com/ Gustavo Turecki https://douglas.research.mcgill.ca/gustavo-turecki/ Rima Slim https://scholar.google.ca/citations?user=UwK8NS8AAAAJ&hl=en Danielle Malo https://www.linkedin.com/in/danielle-malo-a204a174/ Ray Dalio https://www.linkedin.com/in/raydalio/ Nassim Taleb https://en.wikipedia.org/wiki/Nassim_Nicholas_Taleb Timestamps: 00:00 Intro 03:18 Upbringing in Pakistan and Early Influences 07:27 Formative Experiences: Human Genome Sequencing and Aunt's Schizophrenia 13:49 Educational Experience: British System and Academic Rigor 17:21 Economics and Biology: Dual Interests and Decision Making Frameworks 23:31 Decision Making: Opportunity Cost and Probabilistic Thinking 28:51 International Education: Choosing McGill University 34:09 First Lab Experience: Working in a Schizophrenia Research Lab 40:43 Undergraduate Research: Discovering the Gene for Hydatidiform Moles 45:43 Father's Influence on PhD Decision 48:31 Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…
1 🧬Alfredo Andere - LatchBio: Revolutionizing Biopharma Data & Mastering Enterprise Sales (Part 4/4) 46:25
🧬 The Biotech Startups Podcast is powered by Excedr —helping life science startups accelerate R&D and commercialization with founder-friendly equipment leasing. Skip the upfront costs, stay lean, and focus on breakthrough science. As a TBSP listener, you can get exclusive perks through Excedr’s partner network—special savings, promotions, and more. Explore these offers today: https://www.excedr.com/partners . "Focus and commitment to niche ideas have huge payoffs." In part four of our conversation with Alfredo Andere, co-founder of LatchBio, we explore how the company evolved from a simple workflow orchestrator into a comprehensive platform serving biopharma companies and solution providers. Alfredo shares his approach to enterprise sales, emphasizing the importance of speed, focus, and building strong relationships with customers. He also delves into his philosophy on fundraising and the pivotal role of iterative development in creating impactful biotech solutions. Alfredo reflects on the challenges and rewards of working in niche markets, explaining why deep commitment and loyalty to specific problems are essential for long-term success. Whether you’re a first-time founder or an experienced entrepreneur, this episode is packed with actionable insights on building, selling, and scaling in the biotech space. Key topics covered: Iterative product development: Expanding LatchBio’s platform from workflows to data storage and analysis Biopharma vs. solution providers: How LatchBio serves these distinct customer groups Enterprise sales best practices: Qualifying leads and acting as a consultant to customer problems Fundraising strategies: Why early-stage rounds focus on vision and team, while later rounds prioritize traction The power of focus: Avoiding the trap of optionality and scaling only when ready If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening. Subscribe to the Podcast: Apple: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Spotify: https://open.spotify.com/show/2PSL162R2s0zOwU5913Zv4 Youtube: https://www.youtube.com/@thebiotechstartupspodcast Website: https://www.thebiotechstartupspodcast.com/ Find our guest, Alfredo Andere, at these links: LinkedIn: https://www.linkedin.com/in/alfredoandere/ Website: https://www.linkedin.com/company/latchbio/ Find our host, Jon Chee, at these links: LinkedIn: https://www.linkedin.com/in/jonchee Learn more about Excedr: LinkedIn: https://www.linkedin.com/company/excedr/ Website: https://www.excedr.com Intro & Outro Songs Created by OkKyojin, Owned by Excedr: Website: https://flow.page/kyojin Resources & Articles: Viktor Frankl's "Man’s Search for Meaning": https://www.goodreads.com/book/show/4069.Man_s_Search_for_Meaning Lux Capital’s Article: Why High-Throughput Bio Research Needs Better Tools: Immediately: https://www.luxcapital.com/content/why-high-throughput-bio-research-needs-better-tools-immediately AlphaFold 2: https://alphafold.ebi.ac.uk/ Bulk RNA-seq Analysis Tools: https://en.wikipedia.org/wiki/List_of_RNA-Seq_bioinformatics_tools Paul Graham’s "How to Raise Money": https://www.paulgraham.com/fr.html Companies, Universities, & People mentioned: Latch Bio: https://latch.bio Illumina: https://illumina.com Oxford Nanopore Technologies: https://nanoporetech.com 10x Genomics: https://10xgenomics.com Fluent BioSciences: https://www.fluentbio.com/ Scale 10x: https://startupmission.kerala.gov.in/pages/scale10x Complete Genomics: https://www.completegenomics.com Kenny Workman: https://www.linkedin.com/in/kennyworkman Kyle Giffin: https://www.linkedin.com/in/kylegiffin Aidan Abdulali: https://www.linkedin.com/in/aidanabdulali Nathan Manske: https://www.linkedin.com/in/nathan-manske-0232a192/ Michael Paliotti: https://www.linkedin.com/in/michael-paliotti Timestamps: 00:00 Intro 01:56 LatchBio’s Evolution and Iterative Development 08:20 Biopharma vs. Solution Providers 14:01 Enterprise Sales Philosophy 23:38 Fundraising Strategies and Team Building 34:59 Future Vision for LatchBio 39:36 Closing Thoughts and Shoutouts 43:46 Advice to 21-Year-Old Self 46:21 Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…
1 🧬Alfredo Andere - LatchBio: Building Biotech Data Tools to Revolutionize Life Sciences (Part 3/4) 32:14
🧬The Biotech Startups Podcast is powered by Excedr —helping life science startups accelerate R&D and commercialization with founder-friendly equipment leasing. Reduce upfront equipment costs. Accelerate R&D. Reach commercial milestones faster. 🎁TBSP listeners get exclusive offers through Excedr’s partner network—including special discounts, promos, and more: https://www.excedr.com/partners . "A lot of decisions when you're doing a startup come down to being naive enough to not know how hard it's going to be—and taking that leap of faith." In part three of our conversation with Alfredo Andere, co-founder of LatchBio, we dive into the early days of building a biotech startup from scratch. Alfredo shares how his team’s chemistry and blind faith led them to drop out of college and fully commit to solving biotech’s data infrastructure challenges. He details their rigorous market research process, which involved conducting hundreds of user interviews, and how this groundwork helped them raise an oversubscribed $5 million seed round led by Lux Capital. Alfredo also reflects on the stark contrast between cutting-edge data tools at tech giants like Google and the outdated methods still used in biotech, emphasizing the massive opportunity to revolutionize life sciences. Key topics covered: Building trust and chemistry as a founding team: The decision to drop out and go all-in on LatchBio Biotech’s data problem: Why outdated tools are holding back life sciences innovation Market research done right: 200+ pages of notes and six paying customers before launching a product Raising $5M in seed funding: How preparation and customer validation gave LatchBio a competitive edge Lessons on naivete in entrepreneurship: Why bold risks are essential for tackling big problems If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening. Subscribe to the podcast: Apple: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Spotify: https://open.spotify.com/show/2PSL162R2s0zOwU5913Zv4 Youtube: https://www.youtube.com/@excedr Website: https://www.thebiotechstartupspodcast.com/ Find our guest, Alfredo Andere, at these links: LinkedIn: https://www.linkedin.com/in/alfredoandere/ Website: https://www.linkedin.com/company/latchbio/ Find our host, Jon Chee, at these links: LinkedIn: https://www.linkedin.com/in/jonchee Learn more about Excedr LinkedIn: https://www.linkedin.com/company/excedr/ Website: https://www.excedr.com Resources and articles: Viktor Frankl's "Man’s Search for Meaning": https://www.goodreads.com/book/show/4069.Man_s_Search_for_Meaning Lux Capital Insights: https://www.luxcapital.com/riskgaming#content The Acquired Podcast featuring Jensen Huang: https://www.acquired.fm/episodes/jensen-huang Taiwan Incubator Program: https://startup.sme.gov.tw/en/ia Next Generation Sequencing (NGS): https://www.excedr.com/blog/next-generation-sequencing-101 Google and Facebook Data Infrastructure: https://medium.com/illumination/facebook-google-and-digital-public-infrastructure-ee854e1896eb Bulk RNA-seq Analysis Tools: https://en.wikipedia.org/wiki/List_of_RNA-Seq_bioinformatics_tools Machine Learning Applications in Biotech: https://cdn.fortunejournals.com/articles/ai-and-machine-learning-in-biotechnology-a-paradigm.pdf Companies, universities, & people mentioned: LatchBio: https://latch.bio/ Lux Capital: https://www.luxcapital.com Google: https://www.google.com Facebook (Meta): https://www.facebook.com Excedr: https://www.excedr.com Vivos Therapeutics: https://www.vivos.com Kenny Workman: https://www.linkedin.com/in/kennyworkman Kyle Giffin: https://www.linkedin.com/in/kylegiffin Brandon Reeves: https://www.linkedin.com/in/brandonreeves1 Jensen Huang: https://www.linkedin.com/in/jenhsunhuang/ Timestamps: 00:00 Intro 01:56 Team Chemistry and Founding Relationships 04:30 Exploring Different Project Ideas 06:34 The Decision to Drop Out of College 09:00 The Role of Naivete in Entrepreneurship 11:38 Biotech vs. Computer Science: Understanding Complex Systems 13:14 Taiwan Incubator Experience 17:22 Market Research: 200+ Pages of User Interviews 21:05 Biotech's Data Infrastructure Problem 25:21 Raising an Oversubscribed $5M Seed Round 29:38 The Future of Biotech Data Analysis 30:30 Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…
1 🧬Alfredo Andere - LatchBio: College Friends, Biotech Beginnings & Thoughtful Persistence (Part 2/4) 34:59
"You will be surprised what you can achieve with thoughtful persistence." In part two of our conversation with Alfredo Andere, co-founder of LatchBio, we dive into his transformative journey at UC Berkeley, where he developed a passion for machine learning and neuroscience. Alfredo shares how his persistence and curiosity helped him join the highly competitive Machine Learning at Berkeley club, which became a pivotal moment in shaping his entrepreneurial mindset. He reflects on the lessons learned from internships at Facebook, UCSF, and Google Brain, and how these experiences clarified his desire to pursue startup life over a traditional tech career. Alfredo also recounts the early days of working with his co-founders on ambitious projects, including their first failed startup attempt, and how those challenges led them to explore opportunities in biotech. This episode offers valuable insights into navigating uncertainty, embracing trial and error, and building meaningful collaborations. Key topics covered: The power of thoughtful persistence: How Alfredo's determination led to joining a top-tier student organization at UC Berkeley. Lessons from internships: Insights gained from working at Facebook, UCSF, and Google Brain—and why he ultimately chose startups. The importance of community: How Machine Learning at Berkeley shaped Alfredo's leadership skills and introduced him to like-minded peers. Early startup lessons: The challenges of building a product without understanding the market and the value of user research. Transitioning to biotech: How Alfredo’s passion for neuroscience evolved into tackling critical problems in life sciences with his co-founders. If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening. Subscribe to the podcast: Apple: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Spotify: https://open.spotify.com/show/2PSL162R2s0zOwU5913Zv4 Youtube: https://www.youtube.com/@excedr Website: https://www.thebiotechstartupspodcast.com/ Find our guest, Alfredo Andere, at these links: LinkedIn: https://www.linkedin.com/in/alfredoandere/ Website: https://www.linkedin.com/company/latchbio/ Find our host, Jon Chee, at these links: LinkedIn: https://www.linkedin.com/in/jonchee Learn more about Excedr LinkedIn: https://www.linkedin.com/company/excedr/ Website: https://www.excedr.com Resources and articles: Machine Learning at Berkeley (ML@B): https://ml.berkeley.edu/ Viktor Frankl's "Man’s Search for Meaning": https://www.goodreads.com/book/show/4069.Man_s_Search_for_Meaning Neuralink Research Paper: https://pmc.ncbi.nlm.nih.gov/articles/PMC6914248/ Berkeley NeuroDust Project: https://engineering.berkeley.edu/news/2016/11/neural-dust/ TensorFlow by Google Brain: https://www.tensorflow.org/ Bulk RNA-seq: https://www.scdiscoveries.com/support/what-is-bulk-rna-sequencing/ AlphaFold 2: https://alphafold.ebi.ac.uk/ Companies, universities, & people mentioned: Dyno Therapeutics: https://www.dynotx.com/ LatchBio: https://latch.bio/ Facebook (Meta): https://www.facebook.com Google Brain (now part of Google DeepMind): https://research.google/brain Neuralink: https://neuralink.com University of California, San Francisco (UCSF): https://www.ucsf.edu Kenny Workman: https://www.linkedin.com/in/kennyworkman Kyle Giffin: https://www.linkedin.com/in/kylegiffin Timestamps: 00:00 Intro 01:28 College Friendships and Early Seeds of LatchBio 03:46 Joining Machine Learning at Berkeley: Challenges and Growth 07:01 Transformational Impact of Student Organizations 12:08 Running the Machine Learning Club at Berkeley: Leadership Lessons 18:14 Introduction to Neuroscience and Life Sciences 21:38 Internships at Facebook, UCSF, and Google Brain 26:36 Lessons from Early Startup Attempts 29:12 Dropping Out of Berkeley to Pursue Entrepreneurship Full-Time 32:05 Balancing Academic and Entrepreneurial Pursuits 33:11 Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…
🧬 The Biotech Startups Podcast is powered by Excedr —helping life science startups accelerate R&D and commercialization with founder-friendly equipment leasing. Skip the upfront costs, stay lean, and focus on breakthrough science. As a TBSP listener, you can get exclusive perks through Excedr’s partner network—special savings, promotions, and more. Explore these offers today: https://www.excedr.com/partners . "I had to make a decision because I knew that if nothing changed, I was just gonna fail out of EECS. I remember EECS actually sent me a letter where they were like, 'Hey, if your GPA continues this low, you will be kicked out next semester.'" In part one of our conversation with Alfredo Andere, we delve into his journey from Mexico to the prestigious EECS program at UC Berkeley. Alfredo shares his early fascination with technology, the challenges of adapting to a new educational system, and the pivotal moments that shaped his academic and personal growth. Raised in various cities across Mexico, Alfredo's passion for technology was sparked by reading biographies of tech leaders like Steve Jobs and Elon Musk. His entrepreneurial spirit emerged early when he organized a forum that attracted high-profile speakers, including former Mexican presidents, to his all-boys Catholic high school. Despite initial struggles with calculus at Berkeley, Alfredo's determination and commitment to his studies ultimately led to his success in the competitive EECS program. Key topics covered: Upbringing in Mexico: Moving between cities and experiencing different cultures Early tech inspiration: Impact of reading biographies and following Apple keynotes High school innovation: Creating a forum with 4,000 attendees and notable speakers Transition to US education: Challenges of applying to and choosing Berkeley Academic resilience: Overcoming initial struggles in EECS through intense dedication If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening. Subscribe to the podcast: Apple: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Spotify: https://open.spotify.com/show/2PSL162R2s0zOwU5913Zv4 Youtube: https://www.youtube.com/@excedr Website: https://www.thebiotechstartupspodcast.com/ Find our guest, Alfredo Andere, at these links: LinkedIn: https://www.linkedin.com/in/alfredoandere/ Website: https://www.linkedin.com/company/latchbio/ Find our host, Jon Chee, at these links: LinkedIn: https://www.linkedin.com/in/jonchee Learn more about Excedr LinkedIn: https://www.linkedin.com/company/excedr/ Website: https://www.excedr.com Resources and articles: AWS (Amazon Web Services): https://aws.amazon.com/ AstraZeneca: https://www.astrazeneca.com/ GCP (Google Cloud Platform): https://cloud.google.com/ EVO https://pmc.ncbi.nlm.nih.gov/articles/PMC6589126/ AlphaFold 2: https://alphafold.ebi.ac.uk/ Dyno Therapeutics: https://www.dynotx.com/ Bulk RNA-seq: https://www.scdiscoveries.com/support/what-is-bulk-rna-sequencing/ Companies, universities, & people mentioned: Apple: https://www.apple.com/ LatchBio: https://latch.bio/ UC Berkeley: https://www.berkeley.edu/ Uri Levine: https://il.linkedin.com/in/uri-levine Felipe Calderon: https://www.linkedin.com/in/felipe-calderon-9b104a23/?originalSubdomain=mx Vicente Fox: https://www.linkedin.com/in/vincente-fox-president/?originalSubdomain=mx Timestamps: 00:00 Intro 02:50 Alfredo's upbringing in Mexico and early influences 05:24 Reading biographies of tech leaders and early inspirations 08:09 Developing interest in technology and Apple 11:51 High school experience in Mexico 15:40 The importance of relationships in Mexican business culture 20:10 Creating a forum that attracted high-profile speakers 23:13 The power of persistence and networking 27:10 Application process to US universities and choosing Berkeley 31:22 First experiences at Berkeley and academic challenges 35:14 Struggling with calculus and the pivotal decision to commit 35:39 Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…
1 🧬 Michael Paliotti - MilliporeSigma: Master Biotech Sales & Build High-Performance Teams (Part 4/4) 31:01
🧬 The Biotech Startups Podcast is powered by Excedr —helping life science startups accelerate R&D and commercialization with founder-friendly equipment leasing. Skip the upfront costs, stay lean, and focus on breakthrough science. As a TBSP listener, you can get exclusive perks through Excedr’s partner network—special savings, promotions, and more. Explore these offers today: https://www.excedr.com/partners . "I see myself as a player coach. I really try to do what I can to be in the trenches as much as I can. I'm out on the field." In the final part of our conversation with Michael Paliotti, we delve into his extensive experience in biotech sales and leadership. Michael shares insights on the nuances of working with different types of clients, from academia to large pharma and emerging biotech companies. He discusses his transition into management during the COVID-19 pandemic and his approach to leading and developing his team. Michael's leadership philosophy emphasizes building strong relationships, both with clients and team members. He stresses the importance of empathy, trust, and removing barriers for his team to succeed. His approach to management is rooted in his own experiences as a sales representative, allowing him to relate to his team's challenges and provide meaningful support. Key topics covered: Tailoring sales approaches for different client types: academia, large pharma, and emerging biotech Transitioning from individual contributor to team manager during the pandemic Leadership philosophy focused on relationship-building and empathy Developing and retaining talent in a competitive industry Long-term career aspirations and the importance of mentorship in biotech If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening. Subscribe to the podcast: Apple: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Spotify: https://open.spotify.com/show/2PSL162R2s0zOwU5913Zv4 Youtube: https://www.youtube.com/@excedr Website: https://www.thebiotechstartupspodcast.com/ Find our guest, Michael Paliotti, at these links: LinkedIn: https://www.linkedin.com/in/michael-paliotti/ Website: http://www.sigmaaldrich.com/ Find our host, Jon Chee, at these links: LinkedIn: https://www.linkedin.com/in/jonchee Learn more about Excedr LinkedIn: https://www.linkedin.com/company/excedr/ Website: https://www.excedr.com Resources & Mentions: Resources and articles: University of Notre Dame Biology Program: https://biology.nd.edu/undergraduate/programs-of-study/biology-major/ Duquesne University Master's Program in Biology: https://www.duq.edu/academics/colleges-and-schools/science-and-engineering/academics/departments-and-programs/biological-sciences/index.php University of Pittsburgh HIV Research Lab: https://dom.pitt.edu/id/research/clinicalresearch/hivclinicalresearch/ Kodak's Research and Development Division: https://www.kodak.com/en/company/page/innovation/ Luminex Multiplexing Equipment: https://www.rndsystems.com/products/luminex-instrumentation Companies, universities, & people mentioned: MilliporeSigma: https://www.sigmaaldrich.com/US/en University of Pittsburgh: https://www.pitt.edu/ Xerox Business Services: https://www.xerox.com/en-us/business-solutions Johnson & Johnson (J&J): https://www.jnj.com/ Novartis: https://www.novartis.com/ Pfizer: https://www.pfizer.com/ University of California, San Diego (UCSD): https://ucsd.edu/ Genoptix: https://www.genoptix.com/ Cellomics: https://www.thermofisher.com/us/en/home/life-science/cell-analysis/cellular-imaging/high-content-screening.html Nucleate: https://nucleate.xyz/ Ronald Montelaro https://www.linkedin.com/in/ronald-montelaro-49558b23/ Jane Berry https://www.linkedin.com/in/jane-berry-40038012/ Kelly Yamagata https://www.linkedin.com/in/kelly-yamagata/ Arunima Kumar https://www.linkedin.com/in/arunmaara/ Tiffany Nguyen https://www.linkedin.com/in/nguyentiffany/ Samantha Odo https://www.linkedin.com/in/samantha-odo-9a39252/ Amela Tsai https://www.linkedin.com/in/amelatsai/ Je'Anna Barrett https://www.linkedin.com/in/connectwithjeanna/ Joe Stachewicz https://www.linkedin.com/in/destinationdigital/ Frédéric Sattler https://www.linkedin.com/in/fr%C3%A9d%C3%A9ric-sattler-58a9a345/ Bernardo Jaramillo https://www.linkedin.com/in/bernardo-jaramillo-06579698/ Darae Jun https://www.linkedin.com/in/darae-jun/ Sumreet Banka https://www.linkedin.com/in/sumreet-banka-73372317/ Candice Sanscartier https://www.linkedin.com/in/candice-sanscartier/ Suzie Shrestha https://www.linkedin.com/in/suzieshrestha/ Timestamps: 00:00 Intro 02:11 Differences in working with academia, large pharma, and small biotechs 06:52 Impact of white glove service on emerging companies 09:25 The interconnected nature of the biotech ecosystem 12:26 Transitioning from individual contributor to team manager 18:09 Leadership philosophy and approach to managing a team 23:23 Long-term mindset and developing institutional knowledge 25:17 Shoutouts to supporters along the way 27:10 Advice to 21-year-old self 28:27 Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…
🧬 The Biotech Startups Podcast is powered by Excedr —helping life science startups accelerate R&D and commercialization with founder-friendly equipment leasing. Skip the upfront costs, stay lean, and focus on breakthrough science. As a TBSP listener, you can get exclusive perks through Excedr’s partner network—special savings, promotions, and more. Explore these offers today: https://www.excedr.com/partners . “Trust takes time—but it lasts longer than any sale.” In part three of our conversation with Michael Paliotti, we dive into his transition from field application scientist to full-time sales at MilliporeSigma. He opens up about his initial hesitation, how he overcame it, and why relationship-building—not quotas—became the foundation of his sales approach. Michael reflects on the experiences that shaped his mindset, from going the extra mile for colleagues to finding interests to genuinely connect over. For him, great sales isn’t about pushing products—it’s about solving problems, building trust, and being present. He also talks about how this philosophy led to unexpected opportunities, like launching a winery with close friends during the pandemic. What started as a casual wine-tasting class turned into a business rooted in the same values that guide his sales career. An experienced team leader, Michael emphasizes coaching through effort and empathy—encouraging his reps to focus on relationships as much as results. His story is a reminder that in biotech sales, success often comes from being helpful, human, and in it for the long haul. Key topics covered : Shifting from scientist to sales and making it work Turning casual conversations into lasting trust Helping customers by going the extra mile Meeting goals without losing the human touch Coaching teams to lead with effort and empathy If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening. Subscribe to the podcast: Apple: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Spotify: https://open.spotify.com/show/2PSL162R2s0zOwU5913Zv4 Youtube: https://www.youtube.com/@excedr Website: https://www.thebiotechstartupspodcast.com/ Find our guest, Michael Paliotti, at these links: LinkedIn: https://www.linkedin.com/in/michael-paliotti/ Website: http://www.sigmaaldrich.com/ Find our host, Jon Chee, at these links: LinkedIn: https://www.linkedin.com/in/jonchee Learn more about Excedr LinkedIn: https://www.linkedin.com/company/excedr/ Website: https://www.excedr.com Resources and articles: Luminex instrumentation: https://www.thermofisher.com/us/en/home/life-science/antibodies/immunoassays/procartaplex-assays-luminex/luminex-instruments.html Unreasonable Hospitality (by Will Guidara): https://www.amazon.com/Unreasonable-Hospitality-Remarkable-Giving-People/dp/0593418573 Excedr equipment leasing: https://www.excedr.com/leasing Capital Lease vs. Operating Lease: https://www.excedr.com/blog/capital-lease-vs-operating-lease Maximizing Equipment ROI: https://www.excedr.com/blog/maximizing-equipment-roi Marketing & Sales Strategies for Biotechs: https://www.excedr.com/blog/marketing-sales-strategies-for-biotechs Companies, universities, & people mentioned: MilliporeSigma: https://www.sigmaaldrich.com/US/en Charles R. Drew University of Medicine and Science: https://www.cdrewu.edu/ UC Davis Viticulture and Enology Program: https://www.ucdavis.edu/majors/viticulture-and-enology 501st Legion: https://www.501st.com/ Paso Robles AVA: https://pasowine.com/paso-robles/ava/ Pacific Wine Services: https://www.pacificwineservices.com/ Volatus Wines: https://www.volatuswine.com/ Midnight Cellars: https://www.midnightcellars.com/ Timestamps: 00:00 Intro 02:50 Getting into biotech sales and and getting interested in winemaking 04:35 Starting a winery during COVID and the story behind it 10:19 Networking in the wine industry and the power of showing up 14:14 Working at MilliporeSigma, embracing relationship-driven strategies 20:45 Building trust through informal conversations 27:47 Going the extra mile for customers and building trust through service 32:46 Transitioning from field scientist to full-time sales at MilliporeSigma 37:12 Coaching sales teams and focusing on long-term value over short-term wins 40:15 Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…
"Success in this industry isn’t just about what you know—it’s about how you connect with people, bring value, and build lasting relationships." In part two of our conversation with Michael Paliotti, we delve into his journey from academic research to industry, and his eventual transition into sales within the biotech sector. Michael shares his experiences working at startups like Cellomics and larger organizations like Novartis, highlighting the pivotal moments that shaped his career path. He discusses the challenges and opportunities that came with each role, emphasizing the importance of relationships and personal branding in his success. Michael's background in both science and business, coupled with his MBA, uniquely positioned him to understand the needs of researchers and effectively communicate the value of products. His transition to a field application scientist role at Millipore, and later to a full-time sales position, showcases his ability to adapt and find his niche in the biotech industry. Michael's approach to sales, focusing on building genuine connections and becoming a trusted resource, led to his recognition as rep of the year and his reputation as an "institution" in the San Diego biotech ecosystem. Key topics covered: Transitioning from academia to roles at Cellomics and Novartis Balancing business education with a biotech career Moving from field application scientist to a full-time sales role Learning to communicate value beyond product features and build trust with customers Making bold moves, from cross-country relocation to industry shifts If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening. Subscribe to the podcast: Apple: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Spotify: https://open.spotify.com/show/2PSL162R2s0zOwU5913Zv4 Youtube: https://www.youtube.com/@excedr Website: https://www.thebiotechstartupspodcast.com/ Find our guest, Michael Paliotti, at these links: LinkedIn: https://www.linkedin.com/in/michael-paliotti/ Website: http://www.sigmaaldrich.com/ Find our host, Jon Chee, at these links: LinkedIn: https://www.linkedin.com/in/jonchee Learn more about Excedr LinkedIn: https://www.linkedin.com/company/excedr/ Website: https://www.excedr.com Resources & Mentions: DARPA (Defense Advanced Research Projects Agency): https://www.darpa.mil/ Novartis GPR 119 diabetes research: https://pmc.ncbi.nlm.nih.gov/articles/PMC5859088/ Cal State San Marcos MBA program: https://www.aacsb.edu/accredited/c/california-state-university-san-marcos Luminex Assays: https://www.rndsystems.com/products/luminex-assays-and-high-performance-assays/discovery-assays Stanford Consortium for Regenerative Medicine: https://www.sanfordconsortium.org/ Genoptix Optophoresis Technology: https://www.bioworld.com/articles/373517-genoptix-series-b-raises-17m-to-push-laser-cell-technology?v=preview Companies & people mentioned: Cellomics: https://www.thermofisher.com/us/en/home/brands/thermo-scientific/cellomics.html Novartis: https://www.novartis.com/ Genoptix: https://genoptix.com/ EMD MilliporeSigma: https://www.emdmillipore.com/ Luminex: https://www.luminexcorp.com/ Thermo Fisher Scientific: https://www.thermofisher.com/ Pete Schultz: https://www.linkedin.com/in/peter-schultz-3254a35 Tina Nova: https://www.linkedin.com/in/tina-nova-phd-7054502 Sean Carnes: https://www.linkedin.com/in/sean-carnes-8b30b51 Cathy Schnabel: https://www.linkedin.com/in/cathy-schnabel-b657b16 Timestamps: 00:00 Intro 02:06 Michael's interest in industry and joining Cellomics 04:59 Working on DARPA grant and biosensors 07:10 Experience during 9/11 and FBI visit 10:26 Importance of product communication and marketing 14:23 Transition to Novartis and larger organization experience 18:52 Pursuing MBA while working at Novartis 22:16 Moving to field application scientist role at Millipore 25:39 Transition to full-time sales position 30:17 Building relationships and personal brand in sales 35:23 Success as a sales representative and becoming an "institution" 41:39 Reflections on career journey and finding the right niche 41:58 Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…
🧬 The Biotech Startups Podcast is powered by Excedr —helping life science startups accelerate R&D and commercialization with founder-friendly equipment leasing. Skip the upfront costs, stay lean, and focus on breakthrough science. As a TBSP listener, you get exclusive perks through Excedr’s partner network—special savings, promotions, and more. Explore these offers today: https://www.excedr.com/partners . "Growing up in a science-driven environment influenced my trajectory, from my father's chemistry background at Kodak to my own experiences in academia and research." In part one of our conversation with Michael Paliotti , Regional Sales Director at Millipore Sigma, we explore his journey from a science-driven upbringing to his early career in research and forensics. Michael shares how his father's work as an organic chemist at Kodak influenced his path into science, his academic experiences at the University of Notre Dame and Duquesne University, and his unexpected detour into optometry school before finding his true calling in research. Michael holds a degree in biology from the University of Notre Dame and a master's degree from Duquesne University. Before joining Millipore Sigma, he honed his skills in academic research at the University of Pittsburgh, forensic science with the Pennsylvania State Police, and biotech startups. Key topics covered: Growing up in a science-driven environment: The influence of Kodak and Rochester's tech industry Navigating academic uncertainty: From pre-med aspirations to finding passion in biology research Hands-on lab experience: Learning the "old-fashioned way" during graduate studies Unexpected career detours: A brief stint in optometry school and forensic science Building professional networks: The importance of mentorship and connections in career progression If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening. Subscribe to the podcast: Apple: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Spotify: https://open.spotify.com/show/2PSL162R2s0zOwU5913Zv4 Youtube: https://www.youtube.com/@excedr Website: https://www.thebiotechstartupspodcast.com/ Find our guest, Michael Paliotti, at these links: LinkedIn: https://www.linkedin.com/in/michael-paliotti/ Website: http://www.sigmaaldrich.com/ Find our host, Jon Chee, at these links: LinkedIn: https://www.linkedin.com/in/jonchee Learn more about Excedr LinkedIn: https://www.linkedin.com/company/excedr/ Website: https://www.excedr.com Resources & Mentions: University of Notre Dame Biology Program: https://biology.nd.edu/undergraduate/programs-of-study/biology-major/ Duquesne University Master's Program in Biology: https://www.duq.edu/academics/colleges-and-schools/science-and-engineering/academics/departments-and-programs/biological-sciences/index.php University of Pittsburgh HIV Research Lab: https://dom.pitt.edu/id/research/clinicalresearch/hivclinicalresearch/ Pennsylvania State Police Forensic Science Program: https://www.upb.pitt.edu/academics/forensic-science-bs Kodak's Research and Development Division: https://www.kodak.com/en/company/page/innovation/ Companies & people mentioned: Kodak: https://www.kodak.com/en/ University of Pittsburgh: https://www.pitt.edu/ Pennsylvania State Police: https://www.pa.gov/agencies/psp.html Xerox Business Services: https://www.xerox.com/en-us/business-solutions MilliporeSigma (formerly EMD Millipore): https://www.sigmaaldrich.com/ Luminex Multiplexing Equipment: https://www.rndsystems.com/products/luminex-instrumentation Ronald Montelaro: https://www.linkedin.com/in/ronald-montelaro-49558b23/ Timestamps: 00:00 Intro 03:23 Michael's background and upbringing in Rochester, NY 07:46 Early exposure to science and the Kodak influence 11:09 University years and initial career aspirations 14:46 Unexpected detour to optometry school 17:35 Post-graduation job at Xerox Business Services 22:00 Decision to pursue a master's degree at Duquesne University 26:35 Graduate school experiences and hands-on lab work 29:03 First job as a research associate at University of Pittsburgh 31:29 Brief stint as a forensic scientist with Pennsylvania State Police 37:35 Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…
🧬 The Biotech Startups Podcast is powered by Excedr —helping life science startups accelerate R&D and commercialization with founder-friendly equipment leasing. Skip the upfront costs, stay lean, and focus on breakthrough science. As a TBSP listener, you get exclusive perks through Excedr’s partner network—special savings, promotions, and more. Explore these offers today: https://www.excedr.com/partners . "In life sciences, time is more important for all stakeholders. Because if you're working in life sciences, you have an obligation. You have a moral obligation to be very efficient, if not optimal." In this final part of our conversation with Stavros , founder and CEO of TileDB, we explore the challenges and opportunities in transforming data management within the life sciences sector. Stavros discusses how smaller organizations often lag behind in adopting innovative solutions due to lack of awareness and reliance on existing tools, while larger companies like big pharma are more proactive in seeking advanced technologies. Stavros highlights the importance of behavioral change in technology adoption, emphasizing that companies should focus on their core competencies rather than building infrastructure. He draws parallels with AWS, which revolutionized server management by allowing companies to focus on their products rather than infrastructure. The conversation also touches on the moral obligation of life sciences companies to optimize efficiency, given the impact on human lives. Key topics covered: Challenges for Smaller Organizations: Overcoming barriers to adopting new technologies due to limited awareness and resources. Adoption Contrast: Big pharma vs. smaller organizations in embracing innovative solutions. Behavioral Change in Technology Adoption: The need for mindset shifts in leveraging external solutions. Efficiency in Life Sciences: The moral obligation to optimize time and resources in the sector. Parallels with AWS: How outsourcing infrastructure can accelerate innovation and focus on core competencies. If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening. Subscribe to the podcast: Apple: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Spotify: https://open.spotify.com/show/2PSL162R2s0zOwU5913Zv4 Youtube: https://www.youtube.com/@excedr Website: https://www.thebiotechstartupspodcast.com/ Find our guest, Stavros Papadopoulos, at these links: LinkedIn: https://www.linkedin.com/in/stavrospap/ Website: https://www.linkedin.com/company/tiledb-inc/ Find our host, Jon Chee, at these links: LinkedIn: https://www.linkedin.com/in/jonchee Learn more about Excedr LinkedIn: https://www.linkedin.com/company/excedr/ Website: https://www.excedr.com Resources & Mentions: Crossing the Chasm by Geoffrey Moore: http://soloway.pbworks.com/w/file/fetch/46715502/Crossing-The-Chasm.pdf Azure (Microsoft's cloud computing service): https://azure.microsoft.com/en-gb/ Companies & people mentioned: MIT: https://www.mit.edu/ TileDB: https://tiledb.com/ AWS (Amazon Web Services): https://aws.amazon.com/ Millipore Sigma: https://www.sigmaaldrich.com/ Y Combinator: https://www.ycombinator.com/ PlayStation: https://www.playstation.com/ Jake Glanville: https://www.linkedin.com/in/jacobglanville Jeff Bezos: https://x.com/jeffbezos?lang=en Timestamps: 00:00 Intro 01:10 Discussion on working with smaller companies and scalable products 02:16 Stavros explains how TileDB can replace solution architects 05:07 Discussion on freeing up resources for high ROI initiatives 06:22 Stavros highlights the difficulty of behavioral changes in adopting new technologies 10:16 Jon reflects on the importance of valuing time in life sciences 12:57 Introduction of TileDB's new product, Carrara 18:16 Discussion on meeting users where they are with Carrara 20:06 Stavros shares his vision for TileDB's future adoption 23:30 Jon expresses enthusiasm for TileDB's impact on health outcomes 26:15 Shoutouts to supporters and team members 29:32 Advice to his 21-year-old self 30:30 Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…
🧬 The Biotech Startups Podcast is powered by Excedr —helping life science startups accelerate R&D and commercialization with founder-friendly equipment leasing. Skip the upfront costs, stay lean, and focus on breakthrough science. As a TBSP listener, you get exclusive perks through Excedr’s partner network—special savings, promotions, and more. Explore these offers today: https://www.excedr.com/partners . "We're wasting money. You're wasting money as an organization, like, hundreds of millions of dollars that can save you that money easily. But you have to start reasoning a little bit differently." In this third part of our conversation with Stavros Papadopoulos , founder and CEO of TileDB, we delve into the company's ambitious vision to revolutionize data management in the life sciences sector. Stavros shares the journey of TileDB from its inception as a highly technical solution to its current position as a potential game-changer in how organizations handle diverse data types. He discusses the challenges of selling innovative solutions to large pharmaceutical companies and the stark contrast in adoption between big pharma and smaller organizations. Stavros, with his background as a technologist from MIT, details the early days of TileDB, emphasizing the intense focus on technological innovation and performance optimization. He describes the company's evolution from a small team of highly skilled engineers to securing significant funding and attracting major customers in the life sciences sector. Throughout the conversation, Stavros highlights the philosophical aspect of TileDB's mission, stressing its potential impact on accelerating scientific discovery and ultimately saving lives. Key topics covered: TileDB's Vision for a Multimodal Database: Replacing fragmented data management systems Challenges in Selling Innovative Solutions: Large pharmaceutical companies as a target market The Contrast Between Big Pharma & Smaller Organizations: Adopting new technologies The Philosophical Drive Behind TileDB's Mission: Accelerating scientific discovery Organizational Inertia & Decision-Making Complexities: Enterprise software adoption If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening. Subscribe to the podcast: Apple: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Spotify: https://open.spotify.com/show/2PSL162R2s0zOwU5913Zv4 Youtube: https://www.youtube.com/@excedr Website: https://www.thebiotechstartupspodcast.com/ Find our guest, Stavros Papadopoulos, at these links: LinkedIn: https://www.linkedin.com/in/stavrospap/ Website: https://www.linkedin.com/company/tiledb-inc/ Find our host, Jon Chee, at these links: LinkedIn: https://www.linkedin.com/in/jonchee Learn more about Excedr LinkedIn: https://www.linkedin.com/company/excedr/ Website: https://www.excedr.com Resources & Mentions: Crossing the Chasm by Geoffrey Moore: http://soloway.pbworks.com/w/file/fetch/46715502/Crossing-The-Chasm.pdf Intel's Parallel Computing Lab: https://faculty.cc.gatech.edu/~echow/ipcc/ Intel Science and Technology Center for Big Data at MIT CSAIL: http://hammer.csail.mit.edu/ Hong Kong University of Science and Technology: https://hkust.edu.hk/ AWS (Amazon Web Services): https://aws.amazon.com/ Azure (Microsoft's cloud computing service): https://azure.microsoft.com/en-gb/ Companies & people mentioned: Intel: https://www.intel.com/ MIT: https://www.mit.edu/ TileDB: https://tiledb.com/ Broad Institute: https://www.broadinstitute.org/ Silicon Valley Bank: https://www.svb.com/ Browne Consulting: https://browneconsulting.com/ Snowflake: https://www.snowflake.com/ Databricks: https://www.databricks.com/ Seth Shelnutt: https://www.linkedin.com/in/seth-shelnutt/ Dimitris Papadias: https://cse.hkust.edu.hk/admin/people/faculty/profile/dimitris Yufei Tao: https://www.linkedin.com/in/yufei-tao-328b0b251/?originalSubdomain=hk Timestamps: 00:00 Intro 01:18 Early days of TileDB and its mission 06:36 Building a high-performance team and securing early customers 09:22 Discussing the vision behind TileDB 12:11 The problem of data infrastructure complexity 16:26 TileDB as a multimodal database for discovery 19:27 The inefficiency of in-house database solutions in pharmaceuticals 23:09 Overcoming organizational inertia in adopting new technologies 28:20 The necessity of TileDB for drug discovery 29:48 Differences in working with smaller vs. larger organizations 33:21 Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…
🧬 The Biotech Startups Podcast is powered by Excedr —helping life science startups accelerate R&D and commercialization with founder-friendly equipment leasing. Skip the upfront costs, stay lean, and focus on breakthrough science. As a TBSP listener, you get exclusive perks through Excedr’s partner network—special savings, promotions, and more. Explore these offers today: https://www.excedr.com/partners . "Serendipity plays a big role, but you need to chase it, man. You need to [chase it] and you need to perform. You need to deliver [on] your end of the deal." In part two of our conversation with Stavros Papadopoulos , founder of TileDB, we delve into his journey from academia to entrepreneurship. Stavros shares his experiences at MIT and Intel, and the serendipitous events that led to the founding of his company. He details the transition from working on cutting-edge database systems to identifying a market need in the life sciences sector, particularly in handling complex genomic data. Stavros's background in computer science and his work at the intersection of Intel and MIT uniquely positioned him to tackle the challenges of building a new type of database system. His journey highlights the importance of proactivity, networking, and being prepared for unexpected opportunities. He also shares valuable insights on the realities of starting a database company, including the significant funding requirements and the necessity of continuous learning. Key topics covered: Transition from academia to entrepreneurship: Seizing opportunities at MIT and Intel Developing TileDB: C reating a novel database system for complex data types Fundraising journey: From angel investors to venture capital Challenges of starting a database company: High costs and talent requirements Importance of mentorship and building win-win relationships in tech entrepreneurship: Key strategies for success If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening. Subscribe to the podcast: Apple: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Spotify: https://open.spotify.com/show/2PSL162R2s0zOwU5913Zv4 Youtube: https://www.youtube.com/@excedr Website: https://www.thebiotechstartupspodcast.com/ Find our guest, Stavros Papadopoulos, at these links: LinkedIn: https://www.linkedin.com/in/stavrospap/ Website: https://www.linkedin.com/company/tiledb-inc/ Find our host, Jon Chee, at these links: LinkedIn: https://www.linkedin.com/in/jonchee Learn more about Excedr LinkedIn: https://www.linkedin.com/company/excedr/ Website: https://www.excedr.com Mentions: Resources & Articles: Disciplined Entrepreneurship: 24 Steps to a Successful Startup by Bill Aulet: https://www.d-eship.com/ Zero to IPO by Frederic Kerrest: https://www.linkedin.com/pulse/book-day-zero-ipo-frederic-kerrest-summary-mircea-ioan-soit-kvspe/ TileDB database technology: https://cloud.tiledb.com/academy/what-is-tiledb/ Genomics DB (precursor to TileDB): https://www.tiledb.com/blog/population-genomics-data-with-tiledb MIT Technology Licensing Office: https://tlo.mit.edu/ Broad Institute's VCF (Variant Call Format): https://www.broadinstitute.org/publications/broad12186 Rady Children's Institute for Genomic Medicine (RCIGM): https://radygenomics.org/begin-ngs-newborn-sequencing/ UK Biobank: https://www.ukbiobank.ac.uk/ Companies & People: Intel: https://www.intel.com/ MIT: https://www.mit.edu/ TileDB: https://tiledb.com/ Broad Institute: https://www.broadinstitute.org/ Nexus Venture Partners: https://nexusvp.com/ Sam Madden: https://www.linkedin.com/in/samuel-madden-8ba0835/ Frederic Kerrest: https://www.linkedin.com/in/fkerrest/ Timestamps: 00:00 Intro 01:24 Transitioning from Hong Kong to MIT/Intel 11:30 The importance of proactivity and hustle in seizing opportunities 20:59 Working on database systems at MIT/Intel 29:08 The serendipitous encounter that led to starting TileDB 32:16 Developing TileDB: A database for non-tabular data and machine learning 35:30 Solving scalability issues for the Broad Institute 36:55 Raising initial funding and spinning out TileDB from MIT/Intel 37:26 Challenges of starting a database business 38:15 Structuring TileDB's launch as a win-win for all stakeholders 39:47 Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…
accelerate R&D and commercialization with founder-friendly equipment leasing. Skip the upfront costs, stay lean, and focus on breakthrough science. As a TBSP listener, you get exclusive perks through Excedr’s partner network—special savings, promotions, and more. Explore these offers today: https://www.excedr.com/partners . "If you are capable of acquiring knowledge, of applying the knowledge, and you like it, you can succeed. It doesn't matter what it is." In this episode of The Biotech Startups Podcast, we delve into Stavros Papadopoulos ' transformative journey from Greece to Hong Kong, exploring his experiences as a PhD student at the Hong Kong University of Science and Technology. Stavros shares how a chance encounter on a bus and his professor's last-minute recommendation led him to pursue his doctorate in Hong Kong, a decision that would shape his career and personal life. Stavros describes Hong Kong as the "best city in the world," highlighting the perfect balance between intense academic rigor and vibrant city life. He explains how the university's unique environment, with students working late into the night and a campus integrated into the natural landscape, fostered both hard work and adventure. Stavros also touches on his research focus, which evolved from spatiotemporal databases to data security and cryptography, and how he learned valuable skills that continue to shape his career to this day. Key topics covered: The Power of Mentorship: How guidance from family, professors, and peers influenced Stavros' academic journey Choosing Hong Kong: Balancing academic excellence with quality of life in selecting a PhD program HKUST Experience: Rigorous academics, supportive professors, and a vibrant student community Research Evolution: Transitioning from spatiotemporal databases to data security and cryptography Work-Life Balance: Maintaining high academic performance while enjoying Hong Kong's unique offerings If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening. Subscribe to the podcast: Apple: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Spotify: https://open.spotify.com/show/2PSL162R2s0zOwU5913Zv4 Youtube: https://www.youtube.com/@excedr Website: https://www.thebiotechstartupspodcast.com/ Find our guest, Stavros Papadopoulos, at these links: LinkedIn: https://www.linkedin.com/in/stavrospap/ Website: https://www.linkedin.com/company/tiledb-inc/ Find our host, Jon Chee, at these links: LinkedIn: https://www.linkedin.com/in/jonchee Learn more about Excedr LinkedIn: https://www.linkedin.com/company/excedr/ Website: https://www.excedr.com Resources & Mentions: Spatiotemporal Databases: https://en.wikipedia.org/wiki/Spatiotemporal_database Data Security and Cryptography in Database Management: https://datastackshow.com/podcast/what-is-a-universal-database-featuring-stavros-papadopoulos-of-tiledb-inc/ MIT CSAIL: https://www.csail.mit.edu/ TileDB Universal Database: https://docs.tiledb.com/cloud/concepts/universal-data-management Genomics Data Management: https://tiledb.com/blog/population-genomics-is-a-data-management-problem LiDAR Data Processing: https://tiledb.com/blog/analyzing-lidar-and-sar-data-with-capella-space-and-tiledb Big Data in Telecommunications: https://startups.epam.com/blog/big-data-analytics-for-telecommunications Venture Capital Funding for Tech Startups: https://www.investopedia.com/terms/v/venturecapital.asp Companies & people mentioned: Hong Kong University of Science and Technology: https://hkust.edu.hk/ TileDB: https://tiledb.com/ HKUST: https://iau-hesd.net/university/hong-kong-university-science-and-technology MIT: https://www.mit.edu/ Intel: https://www.intel.com/ Dimitris Papadias: https://www.linkedin.com/in/dimitris-papadias-8429b423a Yanis Manolopoulos: https://www.linkedin.com/in/yannis-manolopoulos-47989514/?originalSubdomain=gr Timestamps: 00:00 Intro 01:47 Early Inclination Towards Learning and Competitiveness 03:52 Grandmother's Gift of First Computer 07:23 Cousin's Advice: A Plan for Computer Science and Silicon Valley 12:23 Mentorship and Guidance 17:18 University Experience and Disappointment 21:34 Tips for Getting into Top US Schools 27:36 Serendipitous Encounter on a Bus: Hong Kong Beckons 36:10 Balancing Hard Work and Enjoyment 42:24 Hong Kong's Unique Appeal and University Life 48:20 Research Focus: Spatiotemporal Databases and Data Security 53:06 Data Security and Cryptographic Techniques 53:36 Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…
1 🧬 Becky Beattie: Scaling LaunchBio & Democratizing Biotech Entrepreneurship (Part 2/2) 1:06:16
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Riproduci in seguito Riproduci in seguito Liste Like Like aggiunto🧬 The Biotech Startups Podcast is powered by Excedr —helping life science startups accelerate R&D and commercialization with founder-friendly equipment leasing. Skip the upfront costs, stay lean, and focus on breakthrough science. As a TBSP listener, you get exclusive perks through Excedr’s partner network—special savings, promotions, and more. Explore these offers today: https://www.excedr.com/partners . "If I'm not building something, then I'm probably not going to be doing it for long. That's the fun part." In part two of our conversation with Becky Beattie , CEO of LaunchBio, we explore her journey scaling a national nonprofit dedicated to supporting early-stage life science founders. Becky shares how she transitioned from BioLabs to LaunchBio, initially joining what she jokingly calls "a lunch club," and eventually stepping into leadership during the pandemic. She details LaunchBio's evolution from local programming to a national organization connecting biotech entrepreneurs with critical resources and capital. Becky's background in both science and real estate uniquely positioned her to understand the challenges of biotech startups, particularly around shared lab spaces and ecosystem development. Her leadership at LaunchBio has focused on creating targeted connections between founders and investors while expanding into new markets and launching initiatives for underrepresented entrepreneurs. Key topics covered: Building LaunchBio: From "lunch club" to national nonprofit supporting early-stage life science founders Navigating leadership challenges: Taking the CEO role during a pandemic and pivoting to virtual programming Creating Investor Connect: Developing curated matchmaking between startups and appropriate VCs Expanding biotech ecosystems: Building thriving life science hubs in emerging markets like Dallas Launching HiveBio: A new accelerator program for underrepresented founders in the life sciences If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening. Subscribe to the podcast: Apple: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Spotify: https://open.spotify.com/show/2PSL162R2s0zOwU5913Zv4 Youtube: https://www.youtube.com/@excedr Website: https://www.thebiotechstartupspodcast.com/ Find our guest, Becky Beattie, at these links: LinkedIn: https://www.linkedin.com/in/rebecca-beattie-68927a9/ Website: https://launchbio.org/ Find our host, Jon Chee, at these links: LinkedIn: https://www.linkedin.com/in/jonchee Learn more about Excedr LinkedIn: https://www.linkedin.com/company/excedr/ Website: https://www.excedr.com Resources & Mentions: Resources & articles mentioned: Investor Connect https://launchbio.org/programs/investor-connect/ NextGen VC Podcast https://launchbio.org/nextgen-vc-podcast/ Invest in Cures Forum https://launchbio.org/programs/invest-in-cures/ EDA Build to Scale Grant https://www.eda.gov/funding/programs/build-to-scale UCSD Gene Therapy Initiative https://genetherapy.ucsd.edu/ Companies & people mentioned: LaunchBio: https://launchbio.org/ HiveBio: https://www.hivebio.io/ BioLabs: https://www.biolabs.io/ Pegasus Park https://pegasuspark.com/ Phase Three: https://phasethreere.com/ Biocom: https://www.biocom.org/ Wilson Sonsini: https://www.wsgr.com/ Connect: https://connect.org/ Susie Harborth https://www.linkedin.com/in/sharborth/ Johannes Fruehauf https://www.linkedin.com/in/johannesfruehauf/ Joan Rose https://www.linkedin.com/in/joansrose/ Kelly Huang https://www.linkedin.com/in/kellychuang/ Caroline Okun https://www.linkedin.com/in/brainsarepretty/ Meredith Martindale https://www.linkedin.com/in/meredithmartindale/ Melissa Schmidt https://www.linkedin.com/in/melissakschmidt/ Sasha Farina https://www.linkedin.com/in/sasha-farina/ Nirav Shah https://www.linkedin.com/in/shahnirav321/ Timestamps: 00:00 Intro 02:09 Returning to life sciences and meeting Susie Harborth 04:47 Joining BioLabs and the shared lab space movement 07:33 The origins of LaunchBio as a "lunch club" 12:47 Challenges of shared lab spaces and building biotech ecosystems 20:01 Joining LaunchBio and focusing on early-stage life science founders 25:11 Transitioning LaunchBio during COVID and scaling nationally 31:22 Taking on the CEO role at LaunchBio during the pandemic 37:51 Launching Investor Connect to strategically match startups with VCs 40:17 Building biotech ecosystems in Dallas and other emerging markets 45:17 Launching HiveBio, an accelerator for underrepresented founders 51:20 The Invest in Cures Forum and rare disease funding initiatives 55:54 Closing reflections and shoutouts 01:03:24 Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…
1 🧬 Becky Beattie: From Rural Beginnings to Building a National Biotech Network (Part 1) 1:03:23
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Riproduci in seguito Riproduci in seguito Liste Like Like aggiunto🧬 The Biotech Startups Podcast is powered by Excedr —helping life science startups accelerate R&D and commercialization with founder-friendly equipment leasing. Skip the upfront costs, stay lean, and focus on breakthrough science. As a TBSP listener, you get exclusive perks through Excedr’s partner network—special savings, promotions, and more. Explore these offers today: https://www.excedr.com/partners . “If you’re not enjoying what you’re doing or having fun, why are you doing it? Combine that with hard work and you can achieve cool things.” In part one of our conversation with Becky Beattie , CEO of LaunchBio, we trace her unconventional path from rural San Jose pig farmer to biotech ecosystem builder. Becky shares how her early entrepreneurial grit, scientific curiosity, and business acumen converged to shape her career – including surviving a life-altering spinal injury and pioneering shared lab spaces. Becky holds dual degrees in molecular biology and business from the University of Colorado Boulder. Before leading LaunchBio, she honed her skills in life science sales (SeraCare, Eppendorf), strategic marketing (Comprendia), and real estate innovation (ROC Shared Workspace). Key topics covered: Growing up in 4-H raising pigs: Early lessons in economics and grit Mixing science & business: Blending molecular biology training with business strategy at CU Boulder Cold-calling challenges: Cutting teeth in biotech sales at SeraCare Life Sciences Pivoting through crisis: How a spinal cord injury reshaped career priorities Building the shared lab space movement: Pre-WeWork innovation for life sciences If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening. Subscribe to the podcast: Apple: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Spotify: https://open.spotify.com/show/2PSL162R2s0zOwU5913Zv4 Youtube: https://www.youtube.com/@excedr Website: https://www.thebiotechstartupspodcast.com/ Find our guest, Becky Beattie, at these links: LinkedIn: https://www.linkedin.com/in/rebecca-beattie-68927a9/ Website: https://launchbio.org/ Find our host, Jon Chee, at these links: LinkedIn: https://www.linkedin.com/in/jonchee Learn more about Excedr LinkedIn: https://www.linkedin.com/company/excedr/ Website: https://www.excedr.com Resources & Mentions: Resources & articles mentioned: LaunchBio’s Larger Than Life Program: https://www.launchbio.org/programs/larger-than-life Founder Circle Peer Advisory Forums: https://launchbio.org/programs/founders-circle/ SBIR Grants: https://www.excedr.com/blog/sbir-grants-guide STTR Grants: https://www.excedr.com/blog/sttr-grants-guide Build to Scale Grant Program: https://www.eda.gov/funding-opportunies UCSD Gene Therapy Initiative: https://healthsciences.ucsd.edu/innovation Companies & people mentioned: LaunchBio: https://launchbio.org/ Eppendorf: https://www.eppendorf.com/ BioLabs: https://www.biolabs.io/ Heinrich Netheler: https://corporate.eppendorf.com/en/company/history/founders/ Hans Hinz: https://corporate.eppendorf.com/en/company/history/founders/ Timestamps: 00:00 Intro 03:15 Becky's early life and entrepreneurial experiences 05:55 College years and combining science with business 11:45 First job in biotech sales at SeraCare Life Sciences 16:44 Transition to Eppendorf and capital equipment sales 24:50 Balancing career and family after having children 31:03 Spinal cord injury and two-year recovery period 36:22 Return to work in real estate with ROC shared workspace 42:26 Lessons learned from sales and relationship-building 46:52 The importance of marketing and business strategy 51:23 Reflections on career pivots and personal growth 55:05 Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…
🧬 The Biotech Startups Podcast is powered by Excedr —helping life science startups accelerate R&D and commercialization with founder-friendly equipment leasing. Skip the upfront costs, stay lean, and focus on breakthrough science. As a TBSP listener, you get exclusive perks through Excedr’s partner network—special savings, promotions, and more. Explore these offers today: https://www.excedr.com/partners . “I didn’t set out to be an entrepreneur, but when I couldn’t find a company doing what I believed in, I built my own.” In part two of our conversation with Kate Yen , Founder and CEO of Auron Therapeutics, we explore her journey from leading a novel cancer therapy program at Agios to founding her own biotech company. Kate shares insights into drug development, clinical trials, and the business of biotech, highlighting the importance of translational biology, strategic partnerships, and lean operations in building a successful biotech startup. Kate earned her Ph.D. in Biological Chemistry from UCLA, where she also completed her postdoc. Before Auron, she held roles at Merck and as a UCLA professor before joining Agios Pharmaceuticals, where she led the IDH translational research team behind two FDA-approved IDH mutant inhibitors and co-led the discovery of vorasidenib, a promising glioma therapy now in clinical development. Key topics covered: Navigating clinical trials from discovery to FDA approval with a biomarker-driven approach The importance of translational biology and how Auron integrates it from day one Building a lean biotech startup , from early fundraising to assembling a high-impact team Securing big pharma partnerships in a challenging biotech market Leveraging AI and machine learning to map cancer biology and identify new drug targets If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening. Subscribe to the podcast: Apple: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Spotify: https://open.spotify.com/show/2PSL162R2s0zOwU5913Zv4 Youtube: https://www.youtube.com/@excedr Website: https://www.thebiotechstartupspodcast.com/ Find our guest, Kate Yen, at these links: LinkedIn: https://www.linkedin.com/in/kate-yen-448b22108/ Website: https://www.aurontx.com/ Find our host, Jon Chee, at these links: LinkedIn: https://www.linkedin.com/in/jonchee Learn more about Excedr LinkedIn: https://www.linkedin.com/company/excedr/ Website: https://www.excedr.com Resources & articles mentioned: The Role of Translational Biology in Drug Development: https://www.sciencedirect.com/science/article/abs/pii/S1359644612004060 Navigating Clinical Trials: https://www.fda.gov/patients/learn-about-drug-and-device-approvals/drug-development-process Building & Running a Lean Biotech Startup: https://www.lablaunch.org/post/building-a-lean-biotech-startup Biotech Startup Fundraising Options: https://www.excedr.com/resources/biotech-startup-funding-options Biotech Partnerships - How Partnerships Support R&D: https://www.excedr.com/blog/how-biotech-partnerships-support-research How to Bootstrap Your Biotech Startup & Scale: https://www.excedr.com/resources/how-to-bootstrap-biotech-startup How to Choose the Right CRO for Biotech: https://www.excedr.com/blog/contract-research-organizations How Much Does Lab Space Cost? https://www.excedr.com/blog/how-much-does-lab-space-cost Top VC Firms for Biotech in 2024 - Supporting Innovation & Growth: https://www.excedr.com/blog/top-vc-firms-for-biotech 50 Biotech Seed & Angel Investors to Check Out in 2025: https://www.excedr.com/blog/biotech-seed-and-angel-investors Companies & people mentioned: Auron Therapeutics: https://www.aurontx.com/ Merck: https://www.merck.com/ Agios Pharmaceuticals: https://www.agios.com/ UCLA: https://www.ucla.edu/ Princeton University: https://www.princeton.edu/ Charles Sawyers: https://en.wikipedia.org/wiki/Charles_Sawyers Lew Cantley: https://en.wikipedia.org/wiki/Lewis_C._Cantley David Schenkein: https://www.linkedin.com/in/david-schenkein-md-45342476/ Mike Carey: https://www.uclahealth.org/cancer/members/michael-carey Ruben Shaw: https://www.linkedin.com/in/reuben-shaw-1b8611109/ Timestamps: 00:00 Intro 02:10 Kate Yen’s transition into leadership at Agios 05:39 Navigating clinical trials and biomarker-driven decision-making 10:29 The importance of translational biology in drug development 14:19 Taking the leap to start Auron Therapeutics 18:36 Raising early funding and building a lean biotech startup 26:41 Leveraging AI and machine learning in cancer drug discovery 30:58 Running a biotech startup with a sustainable and transparent culture 41:07 Fundraising strategies to expanding Auron’s platform beyond oncology 47:08 Closing questions for Kate 49:35 Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…
1 🧬 Kate Yen - Part 1 | From Academia to Biotech Leader | Translating Research into Cancer Therapies | Early Days at Merck & Agios 52:15
🧬 The Biotech Startups Podcast, brought to you by Excedr—empowering life science startups with founder-friendly equipment leasing to fast-track R&D and drive commercialization success. 🔬 Know someone in need of lab equipment? Join Excedr’s referral program: Give your friends $1,000 and earn $1,000 for every qualified referral! 💸 🔗 Get your unique referral link here : refer.excedr.com/ZTHETY . Part 1 of 2 : Our guest today is Kate Yen, Founder and CEO of Auron Therapeutics. Auron Therapeutics leverages cutting-edge science and AI-powered analysis to develop next-generation cancer therapies by mapping key drivers of tumorigenesis. Kate earned her Ph.D. in Biological Chemistry from UCLA, where she also completed her postdoc. She held roles at Merck and as a UCLA professor before joining Agios Pharmaceuticals, where she led the IDH translational research team behind two FDA-approved IDH mutant inhibitors and co-led the discovery of vorasidenib, a promising glioma therapy now in clinical development. With deep expertise in preclinical and clinical research, a proven track record in advancing breakthrough therapies, and a passion for oncology, Kate’s journey and insights are invaluable. In this episode, you'll hear about: Kate Yen’s journey from aspiring physician to PhD researcher at UCLA How her postdoc in Charles Sawyers’ lab sparked her passion for translational research Transitioning from academia to industry and learning drug discovery at Merck Taking the leap to join Agios Pharmaceuticals and leading the IDH program The role of collaboration in biotech, from academia to CRO partnerships If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening. Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 https://open.spotify.com/show/2PSL162R2s0zOwU5913Zv4 Find Our Guest, Kate Yen, at these links: https://www.linkedin.com/in/kate-yen-448b22108/ https://www.aurontx.com/ Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/jonchee https://www.excedr.com Excedr Socials & Website LinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ Enriched Notes: Topics Mentioned: Auron Therapeutics: https://www.aurontx.com/ Merck: https://www.merck.com/ Agios Pharmaceuticals: https://www.agios.com/ UCLA: https://www.ucla.edu/ Princeton University: https://www.princeton.edu/ Biotech Startup Fundraising: https://www.excedr.com/resources/biotech-startup-funding-options Biotech Accelerators: https://www.excedr.com/resources/biotech-accelerators Biotech Incubators: https://www.excedr.com/resources/biotech-incubators Top VC Firms for Biotech: https://www.excedr.com/blog/top-vc-firms-for-biotech 50 Biotech Seed & Angel Investors: https://www.excedr.com/blog/biotech-seed-and-angel-investors Guide to Choosing a CRO: https://www.excedr.com/blog/contract-research-organizations Guide to Choosing a CMO: https://www.excedr.com/blog/contract-manufacturing-organizations People Mentioned: Charles Sawyers: https://en.wikipedia.org/wiki/Charles_Sawyers Lew Cantley: https://en.wikipedia.org/wiki/Lewis_C._Cantley David Schenkein: https://www.linkedin.com/in/david-schenkein-md-45342476/ Mike Carey: https://www.uclahealth.org/cancer/members/michael-carey Timestamps: 00:00 Intro 03:01 Kate Yen’s background and Auron Therapeutics’ mission 04:40 Early influences and passion for research 06:27 Choosing academia over medicine, attending UCLA grad school 13:11 Postdoc with Charles Sawyers and translational research 16:58 Transitioning to industry and joining Merck 24:44 Learning drug discovery and pharma culture at Merck 32:32 Taking the leap to Agios Pharmaceuticals 37:42 Leading the IDH program and cancer research 44:43 Collaborating with academic labs and CROs 50:28 Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…
1 🧬 Oguzhan Atay - Part 2 | From Immigrant to Biotech Innovator | Battling Deportation with Nobel Laureate Support | Building a $140M Prenatal Testing Empire 1:05:37
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Riproduci in seguito Riproduci in seguito Liste Like Like aggiunto🧬 The Biotech Startups Podcast, brought to you by Excedr—empowering life science startups with founder-friendly equipment leasing to fast-track R&D and drive commercialization success. 🔬 Know someone in need of lab equipment? Join Excedr’s referral program: Give your friends $1,000 and earn $1,000 for every qualified referral! 💸 🔗 Get your unique referral link here : refer.excedr.com/ZTHETY . Part 2 of 2 : Our guest today is Oguzhan Atay, Co-founder & CEO of BillionToOne. BillionToOne is a precision diagnostics company that quantifies biology to create powerful molecular diagnostics. They work to improve disease detection by counting molecules with their proprietary molecular counting platform. They place patients at the forefront of everything they do and are currently applying their proprietary technology to non-invasive prenatal screening and liquid biopsy. Oguzhan holds a Ph.D. from Stanford in Systems Biology, where he implemented machine learning algorithms and mathematical models to solve specific problems in cellular biology and developed a data-driven mathematical framework to simplify the analysis of complex biological networks. He also has a degree in Molecular Biology from Princeton, as well as minors in Computer Science, Physics, and Applied Mathematics. Oguzhan not only combines deep technical expertise with visionary leadership, but he also has an incredibly inspirational immigrant journey, which makes this series a must-listen for first-time founders, scientists, and industry leaders alike. In this episode, you'll hear about: Oguzhan's journey from Turkey to Stanford BillionToOne's origin, including Y Combinator's role and initial funding challenges The company's innovative prenatal testing approach Expansion into oncology with blood tests for therapy selection and monitoring Oguzhan's personal struggles with immigration issues while starting the company and the support of his mentors If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening! Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 https://open.spotify.com/show/2PSL162R2s0zOwU5913Zv4 Find Our Guest, Oguzhan Atay, at these links: https://www.linkedin.com/in/oatay/ https://billiontoone.com/ Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/jonchee https://www.excedr.com Excedr Socials & Website LinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ Enriched Notes: Topics Mentioned: BillionToOne https://billiontoone.com/ Y Combinator https://www.ycombinator.com/ Common Mistakes Biotechs Make & How to Avoid Them https://www.excedr.com/blog/common-business-mistakes How to Fund an R&D Startup https://www.excedr.com/resources/rd-startup-funding-first-steps Guide to the Venture Capitalist Decision https://www.excedr.com/resources/guide-to-the-venture-capitalist-decision-making-process People Mentioned: David Tsao https://www.linkedin.com/in/davidtsao/ Jim Collins https://en.wikipedia.org/wiki/James_C._Collins Timestamps: 00:00 - Intro 02:28 - The origin of BillionToOne and early challenges 06:48 - Y Combinator's role and initial funding struggles 12:24 - Meeting co-founders and pivoting based on market needs 17:17 - Realizing the importance of the problem in the United States 24:11 - Building physical infrastructure and scaling operations 32:04 - Company culture, hiring philosophy, and growth strategy 38:55 - Expanding into oncology and future product lines 46:40 - Plans for going public and becoming a generational company 53:42 - Shoutouts to supporters and overcoming immigration challenges 59:34 - Advice to his 21-year-old self: keeping an open mind 01:02:51 - Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…
1 🧬 Oguzhan Atay - Part 1 | From Small-Town Turkey to Stanford PhD | Solving Cell Cycle Mysteries | Building a Biotech During a Global Pandemic 1:01:28
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Riproduci in seguito Riproduci in seguito Liste Like Like aggiunto🧬 The Biotech Startups Podcast, brought to you by Excedr—empowering life science startups with founder-friendly equipment leasing to fast-track R&D and drive commercialization success. 🔬 Know someone in need of lab equipment? Join Excedr’s referral program: Give your friends $1,000 and earn $1,000 for every qualified referral! 💸 🔗 Get your unique referral link here : refer.excedr.com/ZTHETY . Part 1 of 2 : Our guest today is Oguzhan Atay, Co-founder & CEO of BillionToOne. BillionToOne is a precision diagnostics company that quantifies biology to create powerful molecular diagnostics. They work to improve disease detection by counting molecules with their proprietary molecular counting platform. They place patients at the forefront of everything they do and are currently applying their proprietary technology to non-invasive prenatal screening and liquid biopsy. Oguzhan holds a Ph.D. from Stanford in Systems Biology, where he implemented machine learning algorithms and mathematical models to solve specific problems in cellular biology and developed a data-driven mathematical framework to simplify the analysis of complex biological networks. He also has a degree in Molecular Biology from Princeton, as well as minors in Computer Science, Physics, and Applied Mathematics. Oguzhan not only combines deep technical expertise with visionary leadership, but he also has an incredibly inspirational immigrant journey, which makes this series a must-listen for first-time founders, scientists, and industry leaders alike. In this episode, you'll hear about: Oguzhan's upbringing in a small Turkish town His early passion for science, deciding to become a scientist at just 10 years old Oguzhan's experience in Turkey's rigorous education system His transition to studying at Princeton Oguzhan's PhD journey at Stanford If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening! Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 https://open.spotify.com/show/2PSL162R2s0zOwU5913Zv4 Find Our Guest, Oguzhan Atay, at these links: https://www.linkedin.com/in/oatay/ https://billiontoone.com/ Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/jonchee https://www.excedr.com Excedr Socials & Website LinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ Enriched Notes: Topics Mentioned: Princeton https://www.princeton.edu/ Stanford https://www.stanford.edu/ BillionToOne https://billiontoone.com/ Common Mistakes Biotechs Make & How to Avoid Them https://www.excedr.com/blog/common-business-mistakes How to Fund an R&D Startup https://www.excedr.com/resources/rd-startup-funding-first-steps Guide to the Venture Capitalist Decision https://www.excedr.com/resources/guide-to-the-venture-capitalist-decision-making-process People Mentioned: Jan Skotheim https://www.linkedin.com/in/jan-skotheim-5157a426a/ Daniel Fisher https://www.linkedin.com/in/daniel-fisher-5466812a/ Jacques Fresco https://www.asbmb.org/asbmb-today/people/082222/in-memoriam-jacques-fresco Max Delbruck https://en.wikipedia.org/wiki/Max_Delbr%C3%BCck Linus Pauling https://en.wikipedia.org/wiki/Linus_Pauling J. Robert Oppenheimer https://en.wikipedia.org/wiki/J._Robert_Oppenheimer Timestamps: 00:00 - Intro 05:41 - Oguzhan's upbringing in Turkey and his parents' emphasis on education 10:22 - Competitive nature of the Turkish education system 15:18 - Oguzhan's decision to attend Princeton for undergraduate studies 21:28 - Integrated science program at Princeton and interdisciplinary approach 26:57 - Oguzhan's experience at the University of Oxford 32:20 - Choosing Stanford for PhD studies 38:21 - Oguzhan's PhD research at Stanford in cell cycle control 43:24 - The importance of resilience in scientific research and entrepreneurship 48:54 - BillionToOne's challenges and creative solutions during the COVID-19 pandemic 55:47 - How overcoming challenges led to unprecedented growth for BillionToOne 59:41 - Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…
1 🧬 Parag Shah - Part 2 | Scaling a Multi-Billion Dollar Life Sciences Fund | Culture, Capital & Entrepreneurship | The K2 HealthVentures Story 1:05:09
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Riproduci in seguito Riproduci in seguito Liste Like Like aggiunto🧬 The Biotech Startups Podcast, brought to you by Excedr—empowering life science startups with founder-friendly equipment leasing to fast-track R&D and drive commercialization success. 🔬 Know someone in need of lab equipment? Join Excedr’s referral program: Give your friends $1,000 and earn $1,000 for every qualified referral! 💸 🔗 Get your unique referral link here : refer.excedr.com/ZTHETY . Part 2 of 2 : Our guest today is Parag Shah, CEO and Founding Managing Director of K2 HealthVentures. K2 HealthVentures is an alternative investment firm that provides flexible, long-term financing solutions to innovative private and public companies in the life sciences and healthcare industries. Committed to making a broader impact, K2 also donates a percentage of its profits to support underserved areas in healthcare. Before founding K2, Parag was Senior Managing Director & Group Head of the Life Sciences practice at Hercules Capital, where he led the fund’s public offering and managed over $2 billion in investments. His deep expertise in life science and healthcare financing was further shaped through key leadership roles at Comerica, Imperial Bank, and BankBoston.Parag’s academic background includes a Masters in Environmental Policy & Planning and a Bachelors in Molecular Biology from MIT, where he conducted research at the Whitehead Institute. With 25+ years of experience at the intersection of science and finance, Parag brings invaluable insights for first-time founders, investors, scientists, and industry leaders navigating the complexities of biotech funding. In this episode, you'll hear about: How Parag scaled Hercules Capital into a multi-billion-dollar life sciences fund The challenges of building a strong company culture in investment firms Why evergreen capital structures can be a game-changer for biotech startups The founding story of K2 HealthVentures and its mission-driven approach How balancing work, family, and entrepreneurship leads to long-term success If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening! Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 https://open.spotify.com/show/2PSL162R2s0zOwU5913Zv4 Find Our Guest, Parag Shah, at these links: https://www.linkedin.com/in/paragshah333/ https://k2hv.com/ Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/jonchee https://www.excedr.com Excedr Socials & Website LinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ Enriched Notes: Topics Mentioned: K2 HealthVentures: https://www.k2healthventures.com/ Hercules Capital: https://www.htgc.com/ Cooley LLP: https://www.cooley.com/ Life Science Cares: https://lifesciencecares.org/ Debt vs. Equity Financing for Biotech Startups: https://www.excedr.com/resources/debt-equity-options-funding-startup Biotech Startup Fundraising: https://www.excedr.com/resources/biotech-startup-funding-options Biotech Startup Support: https://www.excedr.com/resources-category/biotech-startup-support People Mentioned: Roy Liu: https://www.linkedin.com/in/roy-liu-36a35/ Anup Arora: https://www.linkedin.com/in/anup-arora-368ba81/ Meghan FitzGerald: https://www.linkedin.com/in/meghanmfitzgerald/ John Hale: https://www.linkedin.com/in/john-hale-770158b/ Timestamps: 00:00 Intro 01:54 Early days at Hercules and the challenge of biotech debt 06:14 Scaling Hercules, taking it public, and leadership lessons 11:34 Public vs. private investment funds: Key trade-offs and pressures 19:18 Leaving Hercules, taking a break, and redefining priorities 25:35 Avoiding burnout: Balancing work, family, and entrepreneurship 29:04 How time and capital constraints drive better decision-making 33:52 Founding K2 HealthVentures and reshaping biotech venture debt 39:01 Evergreen investment structure and why it benefits startups 46:59 The importance of co-founders, team culture, and shared vision 53:32 Scaling K2, launching a foundation, and investing with purpose 01:02:24 Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…
1 🧬 Parag Shah - Part 1 | Rethinking Biotech Startup Funding | Building Smarter Capital Strategies | Risk, Reward & Leadership in Investing 47:53
🧬 The Biotech Startups Podcast, brought to you by Excedr—empowering life science startups with founder-friendly equipment leasing to fast-track R&D and drive commercialization success. 🔬 Know someone in need of lab equipment? Join Excedr’s referral program: Give your friends $1,000 and earn $1,000 for every qualified referral! 💸 🔗 Get your unique referral link here : refer.excedr.com/ZTHETY . Part 1 of 2 : Our guest today is Parag Shah, CEO and Founding Managing Director of K2 HealthVentures. K2 HealthVentures is an alternative investment firm that provides flexible, long-term financing solutions to innovative private and public companies in the life sciences and healthcare industries. Committed to making a broader impact, K2 also donates a percentage of its profits to support underserved areas in healthcare. Before founding K2, Parag was Senior Managing Director & Group Head of the Life Sciences practice at Hercules Capital, where he led the fund’s public offering and managed over $2 billion in investments. His deep expertise in life science and healthcare financing was further shaped through key leadership roles at Comerica, Imperial Bank, and BankBoston.Parag’s academic background includes a Masters in Environmental Policy & Planning and a Bachelors in Molecular Biology from MIT, where he conducted research at the Whitehead Institute. With 25+ years of experience at the intersection of science and finance, Parag brings invaluable insights for first-time founders, investors, scientists, and industry leaders navigating the complexities of biotech funding. In this episode, you'll hear about: How Parag’s NYC upbringing shaped his leadership and risk-taking mindset His transition from molecular biology to finance and investing Key lessons from his early career in credit and venture lending How he helped shape biotech venture credit and redefine startup financing When to use debt vs. equity in life sciences fundraising If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening! Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 https://open.spotify.com/show/2PSL162R2s0zOwU5913Zv4 Find Our Guest, Parag Shah, at these links: https://www.linkedin.com/in/paragshah333/ https://k2hv.com/ Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/jonchee https://www.excedr.com Excedr Socials & Website LinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ Enriched Notes: Topics Mentioned: K2 HealthVentures: https://www.k2healthventures.com/ Hercules Capital: https://www.htgc.com/ BankBoston (now part of Bank of America): https://en.wikipedia.org/wiki/BankBoston Imperial Bank (acquired by Comerica): https://www.comerica.com/ Venture Debt in Biotech: https://www.fiercebiotech.com/biotech/rise-venture-debt-and-when-biotechs-should-and-shouldnt-use-it Equity vs. Debt Financing: https://www.excedr.com/resources/debt-equity-options-funding-startup Biotech Startup Fundraising: https://www.excedr.com/resources/biotech-startup-funding-options Risk-Taking & Leadership in Startups: Biotech Startup Support: https://www.excedr.com/resources-category/biotech-startup-support Scaling Biotech Companies: https://www.linkedin.com/pulse/scaling-up-overcoming-multifaceted-challenges-growing-rami-levin-njoqe/ People Mentioned: Larry Suskind: https://dusp.mit.edu/people/lawrence-susskind John Ehrenfeld: https://www.linkedin.com/in/johnehrenfeld/ Timestamps: 00:00 Intro 02:59 Parag’s background and early career in finance 06:24 Growing up in NYC and how his parents influenced his mindset 09:42 The impact of education and key mentors in shaping his path 15:11 Transitioning from science to finance, why he left the lab 19:56 Lessons from Bank Boston and entering the world of credit investing 24:32 Moving to Argentina and unexpected entry into banking 29:56 Joining Imperial Bank and the challenges of building biotech venture credit 36:37 Understanding risk-taking and decision-making in biotech financing 42:52 When startups should use debt vs. equity and how venture debt fits into biotech funding 46:02 Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…
1 🧬 Jason C. Foster - Part 2 | Manufacturing Brighter Futures | From Richmond to London: Building a Biotech Empire | Culture Eats Strategy for Breakfast 1:05:39
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Riproduci in seguito Riproduci in seguito Liste Like Like aggiunto🧬 The Biotech Startups Podcast, brought to you by Excedr—empowering life science startups with founder-friendly equipment leasing to fast-track R&D and drive commercialization success. 🔬 Know someone in need of lab equipment? Join Excedr’s referral program: Give your friends $1,000 and earn $1,000 for every qualified referral! 💸 🔗 Get your unique referral link here : refer.excedr.com/ZTHETY . Part 2 of 2 : My guest today is Jason C. Foster, CEO and Executive Director of Ori Biotech. Ori is revolutionizing Cell and Gene Therapy manufacturing through the development of its proprietary platform, IRO®. By automating and standardizing Cell and Gene Therapy manufacturing, Ori and IRO® offer scientists the tools they need to streamline development and support widespread patient access to life-saving treatments. Jason's experience prior to Ori includes more than 20 years of life science leadership in operations, sales, marketing, technology, and investing, during which he developed deep expertise in commercial strategy and a thorough understanding of healthcare markets across the UK, US, and EU. In this episode, you'll hear about: Jason Foster's journey from Virginia to London The critical role of culture in company success Ori Biotech's mission to increase accessibility of cell therapies by developing scalable manufacturing solutions Challenges in commercializing cell therapies and the need to consider commercial viability alongside safety and efficacy Jason's leadership insights, including the concept of being a "trusted advisor" and the importance of transparency in team building If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening! Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Find Our Guest, Jason C. Foster, at these links: https://www.linkedin.com/in/jasoncfoster/ https://oribiotech.com/ Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/jonchee https://www.excedr.com Excedr Socials & Website LinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ Enriched Notes: Topics Mentioned: Ori Biotech https://oribiotech.com/ How to Spin Out of Academia https://www.excedr.com/resources/how-to-spin-out-of-academia-and-into-a-startup How VC-Backed Startups Win When They Lease https://www.excedr.com/blog/how-vc-backed-startups-win-when-they-lease Marketing & Sales Strategies for Startups https://www.excedr.com/blog/marketing-sales-strategies-for-biotechs People Mentioned: Farlan Veraitch https://www.linkedin.com/in/farlan-singh-veraitch-a677112/ Reed Hastings https://www.linkedin.com/in/reedhastings/ Dan Pink https://www.linkedin.com/in/danielpink/ Timestamps: 00:00 - Intro 05:21 - Early days of expanding the business in Europe 10:37 - Reflections on entrepreneurship within a large organization 15:44 - The importance of culture in building a successful company 20:35 - Jason's journey to founding Ori Biotech 27:22 - Building Ori Biotech from the ground up 33:35 - The challenges and potential of cell therapy 39:51 - Ori Biotech's approach to go-to-market strategy 46:09 - The importance of being a trusted advisor to clients 51:10 - Hiring for cultural fit and building a strong team 55:17 - Future plans for Ori Biotech 57:59 - Shoutouts to mentors and supporters 1:00:05 - Advice to his 21-year-old self 1:02:48 - Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…
1 🧬 Jason C. Foster - Part 1 | From Paper Routes to Pharma | Navigating the Dot-Com Bubble | Building a $1B Addiction Medicine Business in 4 Years 53:22
🧬 The Biotech Startups Podcast, brought to you by Excedr—empowering life science startups with founder-friendly equipment leasing to fast-track R&D and drive commercialization success. 🔬 Know someone in need of lab equipment? Join Excedr’s referral program: Give your friends $1,000 and earn $1,000 for every qualified referral! 💸 🔗 Get your unique referral link here : refer.excedr.com/ZTHETY . Part 1 of 2 : My guest today is Jason C. Foster, CEO and Executive Director of Ori Biotech. Ori is revolutionizing Cell and Gene Therapy manufacturing through the development of its proprietary platform, IRO®. By automating and standardizing Cell and Gene Therapy manufacturing, Ori and IRO® offer scientists the tools they need to streamline development and support widespread patient access to life-saving treatments. Jason's experience prior to Ori includes more than 20 years of life science leadership in operations, sales, marketing, technology, and investing, during which he developed deep expertise in commercial strategy and a thorough understanding of healthcare markets across the UK, US, and EU. In this episode, you'll hear about: Jason Foster's early entrepreneurship, from paper routes to creative ventures His transformative time at Columbia Business School, learning valuable lessons about decision-making and international perspectives Jason's entry into healthcare through Merck-Medco His experience growing a small pharmaceutical company from 5 to 400 employees, focusing on addiction medicine The decision to move his family to London to start the European branch of the business If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening! Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Find Our Guest, Jason Foster, at these links: https://www.linkedin.com/in/jasoncfoster/ https://oribiotech.com/ Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/jonchee https://www.excedr.com Excedr Socials & Website LinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ Enriched Notes: Topics Mentioned: University of Virginia https://www.virginia.edu/ Columbia University https://www.columbia.edu/ Merck https://en.wikipedia.org/wiki/Merck_%26_Co . Medco https://en.wikipedia.org/wiki/Medco_Health_Solutions How to Spin Out of Academia https://www.excedr.com/resources/how-to-spin-out-of-academia-and-into-a-startup How VC-Backed Startups Win When They Lease https://www.excedr.com/blog/how-vc-backed-startups-win-when-they-lease Marketing & Sales Strategies for Startups https://www.excedr.com/blog/marketing-sales-strategies-for-biotechs People Mentioned: Larry Sabato https://en.wikipedia.org/wiki/Larry_Sabato Emma Walmsley https://www.linkedin.com/in/emmawalmsleygsk/?originalSubdomain=uk Timestamps: 00:00 Intro 04:51 Early years and entrepreneurial experiences 10:10 College decision process and time at the University of Virginia 18:05 Jason's experience in Washington D.C. and introduction to healthcare policy 20:57 Jason's decision to pursue an MBA at Columbia University 25:04 Memorable lessons from Columbia MBA program 30:47 Jason's transition to the private sector and joining Merck Medco 36:41 Insights on effective sales techniques in the pharmaceutical industry 43:19 Jason's career progression after Columbia and joining Medco Health Solutions 51:02 Jason's move to a small pharmaceutical company in Richmond, Virginia 54:59 Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…
1 🧬 Rafael Rosengarten - Part 4 | Lessons in Scaling a Biotech Startup | Using AI to Transform Cancer Diagnostics | The Genialis Supermodel & krasID 40:45
🧬 The Biotech Startups Podcast, brought to you by Excedr—empowering life science startups with founder-friendly equipment leasing to fast-track R&D and drive commercialization success. 🔬 Know someone in need of lab equipment? Join Excedr’s referral program: Give your friends $1,000 and earn $1,000 for every qualified referral! 💸 🔗 Get your unique referral link here : refer.excedr.com/ZTHETY . Part 4 of 4 : My guest today is Rafael Rosengarten, CEO and Co-Founder of Genialis, the RNA biomarker company. Genialis is reimagining biomarkers for every target, drug, and patient using a combination of precision oncology, RNA, and AI. Rafael, a biomedical research veteran, combines academic excellence with industry innovation. A Dartmouth graduate with a Yale doctorate, he conducted postdoctoral research at Lawrence Berkeley National Laboratory, where he co-invented the j5 DNA assembly tool. As co-founder of the Alliance for AI in Healthcare, he advocates for responsible AI integration in medicine, drawing from his extensive background in evolution, immunology, bioengineering, and genetics. In this episode, you'll hear about: Scaling Genialis during COVID-19 and refining the company’s mission The importance of company culture and building a motivated, cohesive team Developing krasID and the Genialis supermodel to advance cancer diagnostics Raising Series A funding amid biotech market challenges The role of leadership and innovation in driving biotech success and shaping the future of precision oncology. If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening! Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Find Our Guest, Rafael Rosengarten, at these links: https://www.linkedin.com/in/rrosengarten/ https://www.genialis.com/ Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/jonchee https://www.excedr.com Excedr Socials & Website LinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ Enriched Notes: Topics Mentioned: Genialis: https://www.genialis.com/ Taiwania Capital: https://www.taiwaniacapital.com/ Debiopharm Innovation Fund: https://www.debiopharm.com/innovation-fund/ Genialis krasID: https://www.genialis.com/krasid/ Genialis Supermodel: https://www.genialis.com/supermodel/ How to Bootstrap a Biotech: https://www.excedr.com/resources/how-to-bootstrap-biotech-startup Biotech Funding Options: https://www.excedr.com/resources/biotech-startup-funding-options Top VCs in Biotech: https://www.excedr.com/blog/top-vc-firms-for-biotech AI in Cancer Diagnostics: https://www.frontiersin.org/articles/10.3389/fonc.2020.588221/full Predictive Biomarkers in Oncology: https://oncologypro.esmo.org/education-library/esmo-books/esmo-handbooks/translational-research/predictive-biomarkers How Biotech Partnerships Support Research: https://www.excedr.com/blog/how-biotech-partnerships-support-research People Mentioned: Cheng Wu (Founding Partner, Taiwania Capital): https://www.linkedin.com/in/cheng-wu-4614a8a/ Tiasha Stanković (COO, Head of People at Genialis): https://www.linkedin.com/in/tjasakk/?originalSubdomain=si Luka Ausec (Chief Discovery Officer at Genialis): https://www.linkedin.com/in/luka-ausec-378009150/ Miha Štajdohar (Co-founder, CTO at Genialis): https://www.linkedin.com/in/mstajdohar/ Marinka Zitnik (AI Researcher, Associate Professor of Bioinformatics): https://dbmi.hms.harvard.edu/people/marinka-zitnik Timestamps: 00:00 Intro 02:04 Scaling Genialis during COVID-19 and adapting as CEO 04:27 How pivotal clients influence a startup’s growth path 07:15 Addressing critical mistakes in clinical data pipelines 09:43 Redefining Genialis’ mission and fostering strong culture 12:19 Adapting to remote work while reinforcing team values 14:57 Raising Series A funding amid challenging market conditions 20:50 The importance of team culture and resilience 25:37 The Genialis supermodel and its impact on oncology AI 29:12 Two-year vision for Genialis and its three pillars 32:59 Closing questions and advice for entrepreneurs 38:59 Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…
1 🧬 Rafael Rosengarten - Part 3 | Leveraging AI in Precision Medicine | How Predictive Biomarkers Transform Oncology | Lessons from Scaling a Startup 32:09
🧬 The Biotech Startups Podcast, brought to you by Excedr—empowering life science startups with founder-friendly equipment leasing to fast-track R&D and drive commercialization success. 🔬 Know someone in need of lab equipment? Join Excedr’s referral program: Give your friends $1,000 and earn $1,000 for every qualified referral! 💸 🔗 Get your unique referral link here : refer.excedr.com/ZTHETY . Part 3 of 4 : My guest today is Rafael Rosengarten, CEO and Co-Founder of Genialis, the RNA biomarker company. Genialis is reimagining biomarkers for every target, drug, and patient using a combination of precision oncology, RNA, and AI. Rafael, a biomedical research veteran, combines academic excellence with industry innovation. A Dartmouth graduate with a Yale doctorate, he conducted postdoctoral research at Lawrence Berkeley National Laboratory, where he co-invented the j5 DNA assembly tool. As co-founder of the Alliance for AI in Healthcare, he advocates for responsible AI integration in medicine, drawing from his extensive background in evolution, immunology, bioengineering, and genetics. In this episode, you'll hear about: Rafael’s move to Baylor College of Medicine and Houston’s vibrant medical community Innovations in molecular cloning and synthetic biology tools at Baylor Bridging biology and AI through collaborations with University of Ljubljana researchers Founding Genialis and shifting its focus to predictive biomarker development Lessons from biotech pivots that shaped Genialis as a leader in precision oncology If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening! Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Find Our Guest, Rafael Rosengarten, at these links: https://www.linkedin.com/in/rrosengarten/ https://www.genialis.com/ Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/jonchee https://www.excedr.com Excedr Socials & Website LinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ Enriched Notes: Topics Mentioned: Baylor College of Medicine: https://www.bcm.edu/ University of Ljubljana: https://www.uni-lj.si/en/university Genialis: https://www.genialis.com/ Lab Equipment List, Synthetic Biology Research: https://www.excedr.com/blog/lab-equipment-list-for-synthetic-biology-research How to Bootstrap Your Biotech Startup & Scale: https://www.excedr.com/resources/how-to-bootstrap-biotech-startup When & How to Pivot a Biotech Startup: https://www.excedr.com/blog/when-how-to-pivot-a-biotech-startup Biotech Startup Support Resources: https://www.excedr.com/resources-category/biotech-startup-support The Role of Machine Learning in Biotech: https://www.linkedin.com/pulse/machine-learning-biotech-fundamentals-divya-ramamoorthy-blhte/ Predictive Biomarkers in Oncology: https://oncologypro.esmo.org/education-library/esmo-books/esmo-handbooks/translational-research/predictive-biomarkers AI and Omics Analysis in Cancer Research: https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2020.588221/full Collaborative Biotech Partnerships: https://www.excedr.com/blog/how-biotech-partnerships-support-research People Mentioned: Gad Shaulsky: https://www.bcm.edu/people-search/gad-shaulsky-30425 Adam Kuspa: https://www.linkedin.com/in/adam-kuspa-23bab836/ Blaž Zupan: https://www.bcm.edu/people-search/blaz-zupan-33768 Marinka Zitnik: https://www.linkedin.com/in/marinkaz/ Miha Štajdohar: https://www.linkedin.com/in/mstajdohar/?originalSubdomain=si Laura Benjamin: https://www.linkedin.com/in/laura-e-benjamin-04299b34/ Timestamps: 00:00 Intro 02:11 Rafael’s move to Houston and postdoc at Baylor College of Medicine 04:09 Collaborating with mentors and early breakthroughs in molecular cloning 07:01 Joining the Gulf Coast Consortium and blending bench science with computational tools 09:44 Transformative partnership with AI pioneers from the University of Ljubljana 13:30 How early machine learning tools shaped Rafael’s career and perspective 17:04 Founding Genialis and the early challenges of pivoting its focus 19:59 Learning from failures and how they shaped Genialis’ mission 23:21 The role of predictive biomarkers in oncology and their real-world impact 27:59 Lessons learned from biotech pivots and navigating the startup world 31:16 Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…
1 🧬 Rafael Rosengarten - Part 2 | From Marine Biology to Synthetic Biology | Building Biofuel Tools at JBEI | When Academic Labs Embrace Entrepreneurship 34:40
🧬 The Biotech Startups Podcast, brought to you by Excedr—empowering life science startups with founder-friendly equipment leasing to fast-track R&D and drive commercialization success. 🔬 Know someone in need of lab equipment? Join Excedr’s referral program: Give your friends $1,000 and earn $1,000 for every qualified referral! 💸 🔗 Get your unique referral link here : refer.excedr.com/ZTHETY . Part 2 of 4 : My guest today is Rafael Rosengarten, CEO and Co-Founder of Genialis, the RNA biomarker company. Genialis is reimagining biomarkers for every target, drug, and patient using a combination of precision oncology, RNA, and AI. Rafael, a biomedical research veteran, combines academic excellence with industry innovation. A Dartmouth graduate with a Yale doctorate, he conducted postdoctoral research at Lawrence Berkeley National Laboratory, where he co-invented the j5 DNA assembly tool. As co-founder of the Alliance for AI in Healthcare, he advocates for responsible AI integration in medicine, drawing from his extensive background in evolution, immunology, bioengineering, and genetics. In this episode, you'll hear about: Rafael's graduate studies at Yale, where mentors fostered his independent research approach His diverse marine biology and genomics projects, preparing him for synthetic biology Rafael's transition to the Joint BioEnergy Institute (JBEI) for synthetic biology and biofuels research The collaborative environment at JBEI, including access to cutting-edge technology and bioinformatics tool development Rafael's insights on choosing the right lab environment and the growing acceptance of entrepreneurship in academia If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening! Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Find Our Guest, Rafael Rosengarten, at these links: https://www.linkedin.com/in/rrosengarten/ https://www.genialis.com/ Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/jonchee https://www.excedr.com Excedr Socials & Website LinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ Enriched Notes: Topics Mentioned: Yale https://www.yale.edu/ Joint BioEnergy Institute (JBEI) https://www.jbei.org/ Next-Generation Sequencing https://www.excedr.com/blog/next-generation-sequencing-101 How to Spin Out of Academia & Into a Startup https://www.excedr.com/resources/how-to-spin-out-of-academia-and-into-a-startup What Should Investors & Founders Expect From Each Other https://www.excedr.com/resources/investor-founder-expectations How to Fund an R&D Startup https://www.excedr.com/resources/rd-startup-funding-first-steps People Mentioned: Stephen Dellaporta https://www.linkedin.com/in/stephen-dellaporta-442aa611/ Leo Buss https://eeb.yale.edu/people/faculty/leo-buss Barbara McClintock https://en.wikipedia.org/wiki/Barbara_McClintock Christopher Mason https://www.linkedin.com/in/christopher-mason-4972a119/ Jonathan Rothberg https://www.linkedin.com/in/jonathanrothberg/ Jay Keasling https://www.linkedin.com/in/jay-keasling-6783754/ Nathan Hillson https://www.linkedin.com/in/nathan-hillson-73702915/ Timestamps: 00:00 - Intro 02:56 - Rafael's experience with his graduate advisors and diverse research projects 07:45 - Comparison of grad school experience to company building and board members 08:59 - Discussion about Jonathan Rothberg and sequencing developments at Yale 10:06 - Rafael's transition from Yale to the Joint BioEnergy Institute (JBEI) 12:46 - The importance of showing up and making connections in person 16:39 - The value of face-to-face interactions in business and collaboration 20:19 - Challenges in the biotech market and the need for in-person networking 23:11 - Rafael's work at JBEI in synthetic biology and tool development 28:22 - Key takeaways from Rafael's experience at JBEI 30:25 - The importance of entrepreneurship in academia and industry 33:55 - Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…
1 🧬 Rafael Rosengarten - Part 1 | From Salt Marsh to Biotech CEO | Snorkeling into Science | Choosing Marine Biology Over Cooking on a Mediterranean Yacht 30:30
Part 1 of 4 : My guest today is Rafael Rosengarten, CEO and Co-Founder of Genialis, the RNA biomarker company. Genialis is reimagining biomarkers for every target, drug, and patient using a combination of precision oncology, RNA, and AI. Rafael, a biomedical research veteran, combines academic excellence with industry innovation. A Dartmouth graduate with a Yale doctorate, he conducted postdoctoral research at Lawrence Berkeley National Laboratory, where he co-invented the j5 DNA assembly tool. As co-founder of the Alliance for AI in Healthcare, he advocates for responsible AI integration in medicine, drawing from his extensive background in evolution, immunology, bioengineering, and genetics. In this episode, you'll hear about: Rafael's upbringing in rural South Carolina, influenced by his parents' intellectual hippie activist background and nature How his French cell biologist uncle sparked his love for science through snorkeling Rafael's journey at Dartmouth, initially pursuing chemistry but ultimately finding his passion in evolutionary biology and ecology His post-college experiences alternating between scientific research and culinary pursuits The pivotal decision to attend a marine biology program at Friday Harbor instead of accepting an offer to cook on a private yacht If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening! Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Find Our Guest, Rafael Rosengarten, at these links: https://www.linkedin.com/in/rrosengarten/ https://www.genialis.com/ Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/jonchee https://www.excedr.com Excedr Socials & Website LinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ Enriched Notes: Topics Mentioned: Dartmouth https://home.dartmouth.edu/ Bay Wolf https://www.berkeleyside.org/2015/07/01/oaklands-bay-wolf-restaurant-closing-after-40-years Yale https://www.yale.edu/ Chez Panisse https://www.chezpanisse.com/1/ Friday Harbor Laboratories https://fhl.uw.edu/ People Mentioned: Jay Keasling https://www.linkedin.com/in/jay-keasling-6783754/ Mark McPeak https://biology.dartmouth.edu/people/mark-alan-mcpeek David Peart https://www.linkedin.com/in/david-peart-251787302/ Carol Folt https://biology.dartmouth.edu/people/carol-l-folt Leo Buss https://eeb.yale.edu/people/faculty/leo-buss Alice Waters https://en.wikipedia.org/wiki/Alice_Waters Fanny Singer (Waters) https://thefoldmag.com/arts-culture/a-conversation-with-fanny-singer-about-her-mother-daughter-memoir-always-home Jeremiah Tower https://www.linkedin.com/in/jeremiah-tower/ Dan Barber https://en.wikipedia.org/wiki/Dan_Barber Thomas Keller https://en.wikipedia.org/wiki/Thomas_Keller Timestamps: 00:49 Intro 02:48 Rafael's upbringing in rural South Carolina and early influences 05:50 Discussing the impact of Rafael's upbringing on his business philosophy 07:44 Rafael's decision to attend Dartmouth College 10:27 Family influence on Rafael's academic pursuits 12:04 Rafael's experiences at Dartmouth and choosing his major 14:30 Summer internship at Bay Wolf restaurant in Oakland 16:55 Influential professors and classmates at Dartmouth 18:22 Post-graduation experiences and working at Yale 23:20 Comparing cooking experiences on the West Coast and East Coast 26:38 Entering Yale's biomedical program and the Friday Harbor experience 29:48 Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…
1 🧬 Cyriac Roeding - Part 4 | Revolutionizing Cancer Detection & Therapy | Harnessing Synthetic Biology to Reshape Diagnostics | Solving Biotech’s Toughest Problems 37:38
Part 4 of 4 : My guest today is Cyriac Roeding, founder, investor, and CEO of Earli, a company on a mission to transform cancer into a manageable condition. Using innovative gene therapy approaches, Earli’s technology forces cancer cells to produce a synthetic, non-human biomarker—overcoming the limitations of relying on naturally occurring biomarkers that cancer may or may not provide. Cyriac is a serial entrepreneur and investor who has created ventures at the intersection of physical and digital worlds. He has invested in startups like OpenAI and served as CEO of Shopkick, which was acquired for $250 million. His current focus, Earli, has raised nearly $60 million from top investors. Cyriac's journey from launching his first startup at 15 to being named a World Economic Forum Tech Pioneer showcases his valuable insights into building successful startups. In this episode, you’ll hear about: How a Thanksgiving article about Dr. Sam Gambhir inspired the founding of Earli Earli’s groundbreaking approach to revolutionizing cancer detection using synthetic biology The challenges of translating scientific discoveries into real-world clinical applications Overcoming obstacles and achieving breakthroughs in diagnostics and therapeutics Cyriac’s unwavering commitment to transforming cancer into a manageable condition If you enjoy The Biotech Startups Podcast, please consider subscribing, leaving a review, or sharing it with your friends. Thanks for listening! Subscribe to the podcast: https://podcasts.apple.com/us/podcast/the-biotech-startups-podcast/id1679591994 Find Our Guest, Cyriac Roeding, at these links: https://www.linkedin.com/in/cyriacroeding/ https://www.earli.com/ https://www.joinrewind.com/ Find Our Host, Jon Chee, at these links: https://www.linkedin.com/in/jonchee https://www.excedr.com Excedr Socials & Website LinkedIn: https://www.linkedin.com/company/excedr/ Youtube: https://www.youtube.com/@excedr Instagram: https://www.instagram.com/excedr_inc Twitter: https://twitter.com/ExcedrInc Facebook: https://www.facebook.com/excedr TikTok: https://www.tiktok.com/@excedr Podcast Website: https://www.thebiotechstartupspodcast.com/ Enriched Notes: Topics Mentioned: Earli: https://www.earli.com/ Stanford University: https://www.stanford.edu/ Andreessen Horowitz: https://a16z.com/ Marc Benioff: https://www.linkedin.com/in/marcbenioff/ Khosla Ventures: https://www.khoslaventures.com/ Lab Equipment List, Synthetic Biology Research: https://www.excedr.com/blog/lab-equipment-list-for-synthetic-biology-research How to Bootstrap Your Biotech Startup & Scale: https://www.excedr.com/resources/how-to-bootstrap-biotech-startup When & How to Pivot a Biotech Startup: https://www.excedr.com/blog/when-how-to-pivot-a-biotech-startup How to Craft a Pitch Deck for Biotech Investors: https://www.excedr.com/resources/how-to-craft-a-pitch-deck-for-biotech-investors Top VC Firms for Biotech in 2024: https://www.excedr.com/blog/top-vc-firms-for-biotech Biotech Startup Support Resources: https://www.excedr.com/resources-category/biotech-startup-support People Mentioned: Dr. Sam Gambhir: https://en.wikipedia.org/wiki/Sanjiv_Sam_Gambhir David Suhy: https://www.linkedin.com/in/davidsuhy/ Jorge Conde: https://www.linkedin.com/in/jorge-conde-4099225/ Jim Allison: https://faculty.mdanderson.org/profiles/james_allison.html Pam Sharma: https://faculty.mdanderson.org/profiles/padmanee_sharma.html Phil Greenberg: https://www.fredhutch.org/en/faculty-lab-directory/greenberg-philip.html Timestamps: 00:00 Intro 02:08 How a Thanksgiving article about Dr. Sam Gambhir inspired Earli’s founding 05:43 Meeting Dr. Gambhir and learning biology as a non-scientist entrepreneur 09:02 Discovering the “one idea” that led to Earli’s revolutionary synthetic biology approach 12:54 Earli’s mission to transform cancer detection and diagnostics 17:30 Overcoming major challenges and achieving breakthroughs in diagnostics accuracy 21:54 The emotional and scientific legacy of Dr. Gambhir and its impact on Earli’s vision 26:28 Earli’s innovative approach to bridging diagnostics and therapeutics 30:05 The business potential of Earli’s platform for cancer and other diseases 33:04 Cyriac’s advice on taking the road less traveled as an entrepreneur 35:41 Outro The Biotech Startups Podcast gives you a front-row seat to the business and science of building a biotech. Hosted by Jon Chee, CEO of Excedr, the show features honest conversations with founders, execs, and investors about their work, their companies, and how they got there. From scientific breakthroughs to startup lessons, each episode explores what it really takes to grow a life science company—from pre-seed to IPO.…
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