Andrew Huberman: How to Increase Your Dopamine by 60% & Optimize Your Brain’s Response to Stress

On Purpose with Jay Shetty

How do you usually handle stress in your life?

Have you ever tried anything to boost your dopamine levels?

Today, Jay welcomes back Dr. Andrew Huberman, a neuroscientist and professor at Stanford University, known for his insightful work on brain development, neuroplasticity, and the intricate connection between the brain and body. Together, they discuss the neuroscience of friendship, exploring how our deep-rooted need for safety and acceptance plays a pivotal role in our social interactions. They unravel the paradox of modern society, where people feel emotionally distant despite increasing online connections and followers.

Dr. Huberman highlights how our brain circuitry, which governs social bonding and connectedness, is tightly linked to our need for predictability and safety. He breaks down how these fundamental needs influence our relationships, both in early development and throughout adulthood, and how understanding these mechanisms can help combat the loneliness epidemic many experience today.

Jay and Andrew discuss practical tools like sending a simple daily “good morning” text, which may seem trivial but has profound implications for maintaining connection and combating feelings of isolation. They also explore the value of doing hard things, such as cold plunges and structured routines, which anchor our physiology and create a sense of predictability, crucial for mental resilience and creativity.

In this interview, you'll learn:

How to Build Predictability in Relationships

How to Activate Bonding Circuits in the Brain

How to Build Trust Through Consistency

How to Combat Loneliness with Regular Check-Ins

How to Ask Meaningful Questions to Deepen Relationships

How to Build a Reliable Circle of Friends

How to Balance Stress with Breathing Techniques

By embracing small yet powerful habits, we not only improve our own lives but also create a ripple effect of positive connection in the lives of those around us. Now is the time to prioritize real, human connection—and in doing so, enrich every aspect of your life.

With Love and Gratitude,

Jay Shetty

What We Discuss:

• 00:00 Intro
• 04:06 Safety and Acceptance
• 19:12 Healthy Friendships
• 29:39 Predictability
• 38:15 Breathing Protocol
• 51:32 Body Still, Mind Active
• 01:02:15 Tenacity and Willpower
• 01:13:06 Walls of Adrenaline
• 01:18:21 Limiting Cynicism
• 01:24:54 You Can’t Control Everything
• 01:34:29 The Human Narrative
• 01:43:15 Be Yourself

Episode Resources:

• Andrew Huberman | Website
• Andrew Huberman | Instagram
• Andrew Huberman | Facebook
• Andrew Huberman | TikTok
• Andrew Huberman | YouTube
• Andrew Huberman | LinkedIn
• Protocols: An Operating Manual for the Human Body

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