I migliori Mike O Toole podcast (2024)

1
EP 148: Advancing veteran health through the Million Veteran Program with Dr. Mike Gaziano, professor of medicine at Harvard Medical School 35:13

1d ago35:13

35:13

0:00 Intro 2:00 Mike’s career prior to the Million Veteran Program (MVP), how Mike got to work on MVP, and important milestones in the project's evolution 8:30 Future goals for the Million Veteran Program in expanding and diversifying the research cohort 11:00 The roles of various omics in advancing the project's development 14:30 The most meaningf…

1
#112 Paris 2024 Olympics — Professional Climber and Coach Tim Kang on The Results, The Routesetting, The Grades, and The Future of Competitions 2:06:24

1d ago2:06:24

2:06:24

Professional climber, coach, routesetter, and frequent Testpiece podcast guest, Tim Kang, is on the pod this week to share his thoughts about the Paris 2024 Olympics. Tim may be best known for his highball ascents that culminated in the film Focus, but Tim is also a seasoned competition climber with multiple World Cups under his belt. Tim loves com…

1
EP 147: From research to delivering precision medicine in the clinic with Scott Weiss, Professor of Medicine at Harvard University 37:19

9d ago37:19

37:19

0:00 Intro to The Genetics Podcast 01:00 Welcome to Scott 01:55 Scott’s career highlights to date, ranging from epidemiology to the genetics of asthma and chronic obstructive pulmonary disease (COPD) 04:56 How and why Scott decided to transition into genetics 06:30 The advances in our understanding of the genetics of asthma and COPD over the past 2…

1
#111 Tom O’Halloran — How To Do Hard Moves, Using Boards To Climb Better Outside, Toes Knees Hips, Taping Correctly, and What The Olympics Are Like 2:23:48

23h ago2:23:48

2:23:48

Tom O’Halloran is arguably the best climber in Australia. He’s an Olympian, he’s climbed 15a and v14, and done FA’s nearly up to those grades as well. But the reason we wanted to have him on the podcast is because of the amazing YouTube content he puts out. He dives into the nuances of hard climbing in a way that actually helps people climb hard. T…

1
Navigating the Thirds in Relationships with Erin O'Toole and Alannah Frank-Wilson 40:58

16d ago40:58

40:58

In today's episode, Alicia sits down with Erin O'Toole, a Certified Canadian Counsellor and professional life coach, and Alannah Frank-Wilson, a Provisional Psychologist, to delve into the concept of "thirds" in relationships. This episode explores how relationships can be shaped and influenced by people outside of the core partnership, and how to …

1
EP 146: The biology of aging with Austin Argentieri, Research Fellow at Harvard Medical School, Affiliate Member of the Broad Institute, and Research Fellow at Massachusetts General Hospital 43:05

7d ago43:05

43:05

0:00 Intro to The Genetics Podcast 01:00 Welcome to Austin 01:42 What is aging and how should we think about it? 03:50 Discussion of Austin’s recent breakthrough paper on aging, including the questions he set out to answer, and the outcomes of the research 06:32 How Austin’s work focuses on using large-scale population proteomics data to create acc…

1
#110 Ethan Salvo — Lessons From Climbing The Hardest Climb in Squamish [TWICE?!], Internal Vs External Motivations, and Transcending Grades 1:48:11

18d ago1:48:11

1:48:11

Ethan Salvo is back on the podcast! Ethan's first episode (linked here) was a fan favorite so when Josh visited Squamish for a few days they met up do an impromptu live/in-person recording. Since the last recording, Ethan has climbed arguably the hardest climb in Squamish, The Singularity. The experience he had on it was fascinating and made him qu…

1
EP 145: Navigating rare disease drug development regulations with Daniel O’Connor 39:12

23d ago39:12

39:12

0:00 Intro to The Genetics Podcast 01:00 Welcome to Daniel 02:04 Defining rare disease in the age of personalized medicine 04:57 Key touchpoints with the Medicines and Healthcare products Regulatory Agency (MHRA) when developing a new medicine 09:27 Improvements over the course of Daniel’s career when it comes to incentivizing and making the path t…

1
#109 Noah & Benn Wheeler — The World’s Hardest Campus Move, Most Difficult Board Climbs, FA’ing V12 On 1st Day Outdoors, and How This Generation Sees The Future 2:11:36

25d ago2:11:36

2:11:36

Noah Wheeler and Benn Wheeler represent the next generation of climbers. At 21 and 19, they are some of the strongest board climbers in the world and their styles reflect that. They also are bring a unique point of view to the world of climbing content with their YouTube channel, Wheel Rock. These brothers have climbed up to V16 outdoors, FA’d up V…

1
EP 144: Research Roundup with Dr. Veera: breakthroughs in developmental disorders, Parkinson's, SLE, and Alzheimer's 56:48

30d ago56:48

56:48

0:00 Introduction 1:40 A recurrent de novo mutation in a noncoding region of a small nucleolar RNA gene that has been identified as one of the most common causes of neurodevelopmental disorders This pathogenic variant escaped notice for years because it was not located in a protein coding region of the genome It now shows potential as a target for …

1
Healing Generational Trauma and Building Meaningful Relationships with Dayna and Mike Elliot 1:54:39

30d ago1:54:39

1:54:39

In this powerful episode of The Relationship Psychologists, Alicia and Dayna welcome a renowned relationship coach and host of the popular podcasts "Together" and "Menamorphosis," Mike Elliot. Together, they delve into the complex topic of generational trauma and its impact on personal development and relationships. Mike Elliot, a visionary transfo…

1
#108 AJ [Alex Johnson] — 20 Years At The Top, The Evolution Of Climbing, Coaching Top Athletes, Climbing Drills, and Returning From A Major Injury 1:59:27

1M ago1:59:27

1:59:27

AJ has been competing at the highest level for decades. She has won multiple Bouldering World Cups and she climbs just as hard outdoors with her iconic send of The Swarm (v13/14) in Bishop which was recently featured in Reel Rock. AJ also coaches some of the top up and coming Youth Athletes (one of her athletes recently won Nationals), through her …

1
EP 143: Harnessing human data in drug development with Jakob Steinfeldt, Co-Founder and Chief Scientific Officer at Pheiron 36:17

1M ago36:17

36:17

0:00 Intro to The Genetics Podcast 01:00 Welcome to Jakob and background on Pheiron 02:14 What made Jakob decide to start Pheiron, what the company does, and how his scientific background inspired him to found a start-up 5:24 Jakob’s excitement and inspiration around the power and potential of machine learning 07:07 Cardiology and heart failure as …

1
#107 Drew Ruana — Thinking Long Term, Grading The Hardest Blocs, Working Weaknesses, 3 Common Plateaus and How to Get Through Them 2:10:57

1M ago2:10:57

2:10:57

Drew Ruana is one of the strongest boulders in the world. Period. He over a hundred V14+ sends, and lots of then are V16. While some other climbers may have that amount of blocs under their belt, no one has accumulated this many in such a short time. Drew goes into his infamous “Send Colorado” journey, which is his goal to send all V14 and up bould…

1
EP 142: From genome to bedside: How genetics is transforming modern medical practice with Dr. Andrea Gropman 42:45

1M ago42:45

42:45

0:00 Introduction 1:40 Andrea’s background and how she got into the field of genetics, neuroimaging, and metabolic disorders 4:00 Insights into Andrea’s clinical practice, including the diverse families and patients she serves and her approach to clinical decision-making 6:30 How genetics and genomics have changed the diagnostic journey in the last…

1
#106 Felipe Camargo — An Unlikely Path To The Top, Finding Mentors, Training Hard By Yourself, Establishing Next Level Routes in Brazil, and Giving Back 1:36:36

2M ago1:36:36

1:36:36

Felipe Camargo is one of the top climbers in our sport with sends up to 9b and V15. That’s impressive… But what’s more impressive is that he began climbing Brazil where there was no professional climbers, no routes past 8b+, and no modern training facilities. Felipe managed to send the iconic 50m 9a+ Papichulo by mainly training on a 3x3m spray wal…

1
EP 141: Bringing genomics to the clinic with Lori Orlando, Associate Prof at Duke University 43:24

2M ago43:24

43:24

0:00 Intro to The Genetics Podcast 01:00 Welcome to Lori Orlando 03:00 Lori’s career: From mathematical modelling to genetics and family history 05:11 The study that revealed 20% of the general population is at a higher risk of disease than average and needs preventative care 07:36 The first five diseases that Lori started analysing through informa…

1
#105 Tim Kang — Going All In, The Most Important Moments for Growth, Embracing What Others Won’t, and The Difference Between Good and Great 2:07:50

2M ago2:07:50

2:07:50

Tim Kang is a frequent guest on the podcast, but now you get to hear him do a more typical interview. Tim is a professional climber and coach that has competed at the World Cup level, won a Psicobloc competition, climbed v14 and 5.14d, but he is best known for his daring sends of the wildest highballs in Bishop which culminated in the popular film …

1
Creating Secure Relationships: Insights with Erin O'Toole 1:03:50

2M ago1:03:50

1:03:50

Alicia sits down with Erin O'Toole to explore the concept of secure functioning in dating and relationships. Erin, an expert in relationship psychology, shares her wisdom on building strong, healthy connections that stand the test of time. Together, Alicia and Erin dive into the importance of getting clear on the values you seek in a relationship. …

1
EP 140: The future of Electronic Health Records and data analysis with Ben Goldacre 52:51

2M ago52:51

52:51

0:00 Intro to The Genetics Podcast 1:00 Welcome to Ben Goldacre 02:22 Ben’s open data projects at the Bennett Institute and the challenges they aim to tackle 04:03 Using Electronic Health Records (EHR) to help the National Health Service improve care 06:18 The importance of software development within healthcare data and how to manage salary scales…

1
#104 Greg Loh — Bouldering Pioneer, World’s Best Spotter, Belief Over Everything, Epic Midnight Lightning Story, Designing The 5.10 Dragons, and What Makes A Climber GREAT 2:20:47

2M ago2:20:47

2:20:47

Greg Loh was one of the strongest boulders in the world during the mid 90’s and early 00’s. He traveled all over the world putting up FA’s of V13+ and climbing with the best. He competed in WC’s, the X-Games, and even won Nationals twice for speed climbing. He is known for being one of the first people who truly embraced bouldering as a discipline …

1
From Saddles to Healing Hands: Vickie Keam on Equine Osteopathy 1:14:31

2M ago1:14:31

1:14:31

Alicia welcomes Vickie Keam, a passionate advocate for self-evolution and a pioneer in the field of equine osteopathy. With 25 years of experience in her equine business, Vickie shares her remarkable journey from working in a saddle shop to becoming a Master of Osteopathy. Vickie’s story is one of continuous learning and evolution. She began by mak…

1
EP 139: Rare disease breakthroughs using tRNA with Michelle Werner, CEO of Alltrna and CEO-Partner of Flagship Pioneering 44:42

2M ago44:42

44:42

0:00 Intro to The Genetics Podcast. 01:00 Welcome to Michelle. 02:00 Sstop codon diseases and how are they characterised 03:45 Diseases caused by premature stop codons in haploinsufficient genes. 04:35 The role of transfer RNA technology in finding solutions for premature stop codon diseases. 06:16 How Alltrna is engineering tRNAs which can bind to…

1
#103 T&J — The Opposite Of Flow, Woods and Wheelers, Keeping Your Feet On, and Respect Every Climb[er] 1:58:08

2M ago1:58:08

1:58:08

Entitlement is the opposite of flow and perhaps the most damaging frame to have over the long term in your climbing. This can come from training, previous sends, or comp placement. Hear stories about Daniel Woods and other pro-climbers who have avoided this frame. And hear from Tim Kang and Josh Horsley about how they coach others and themselves to…

1
#102 The Tension Crew — Ultimate Board Climbing Deep Dive, History of Boards, Best Board Practices, Training on Boards, The Future of Boards, and Undeniable Vibes 2:26:24

2M ago2:26:24

2:26:24

We love board climbing. And if you do too, or even if you are just board curious, this episode it for you. The history of boards, board training, board ethics, board best practices, the future of boards. BOARDS!! This was a special in person recording in Colorado with part of the Tension Climbing crew (Will Anglin, Michael Rosato, and Quinn Spadafo…

1
EP 138: Personalised medicine using microbiome models with Dr. Almut Heinken 40:22

3M ago40:22

40:22

0:00 Introduction 1:45 Almut’s research experience, including two recent publications on genome-scale metabolic reconstruction human microorganisms Genome-scale metabolic reconstruction of 7,302 human microorganisms for personalized medicine APOLLO: A genome-scale metabolic reconstruction resource of 247,092 diverse human microbes spanning multiple…

1
#101 Dave Burleson — How To Be A Pro Climber, What Pro’s Actually Earn, The Tension Between Passion And Professionalism, and Contract Negotiation 101 2:31:11

3M ago2:31:11

2:31:11

Dave Burleson is one of the top agents for professional climbers. He's part of Reppa Athlete Managment that represents athletes like Sean Bailey, Nathaniel Coleman, Nina Williams, Jesse Grupper… the list goes on, but all of them have been on the podcast so we put them here first! Before being an agent, Dave worked at the iconic brands Petzl and The…

1
EP 137: Mavis Machirori on promoting equity, diversity, and social justice in genomics research 41:40

3M ago41:40

41:40

0:00 Intro 1:30 Mavis’ career arc, from starting as a midwife to researching medical innovation and technology with an emphasis on advocacy and equity 7:00 Systemic issues that are easily overlooked in medical research and advancements Webinar: Participant Diversity: Increasing the Impact of Biomedical Research Webinar 10:00 Addressing Eurocentrici…

1
#100 T&J — The Simple Path To Being Great, The Real Role Of Strength, Dealing With Tweaky Moves, Moonboard 2024, Amazing Media Drops, and Skin Farming 2:03:49

3M ago2:03:49

2:03:49

Episode #100!!!! Thank you all for the support. What a journey it’s been. This episode was an absolute banger that encapsulates a lot of the Testpiece message. Tim and Josh break down the ‘Simple’ path that the best climbers follow to being great. And then they detail the appropriate role that strength plays in this path. They also go over the late…

1
EP 136: Developments in ring chromosome 20 research and advocacy with Allison Watson 40:57

3M ago40:57

40:57

0:00 Introduction 2:00 Allison’s personal journey to researching epilepsy and ring chromosome 20 syndrome 4:00 Biggest challenges families face with ring chromosome 20 syndrome 11:00 Incidence and prevalence of r(20) syndrome, and how we can improve data reliability 21:00 Applying next generation sequencing to r(20) syndrome gene research 29:00 Eng…

1
#99 Nina Williams — Off Route While Free Soloing, The Ultimate Confidence, Being a Professional on Instagram, and The Medium Is The Message 1:49:54

3M ago1:49:54

1:49:54

Nina Williams pushes the limits in every discipline of climbing there is… comps, bouldering, highball bouldering, big wall, sport climbing, and even free soloing. In this episode she takes us through a harrowing experience she had while free soloing the Casual Route of the Diamond, a multi pitch 5.10. Nina ended up off route during the climb and th…

1
EP 135: Integration of newborn sequencing programs into healthcare systems with Dr. Ingrid Holm 41:16

3M ago41:16

41:16

0:00 Introduction 1:30 Ingrid’s initial interests in genetics, paediatrics, and newborn screening 2:45 How the original BabySeq project, a pioneering newborn sequencing program got started, how it’s going, and the launch of BabySeq2 8:45 Lessons from BabySeq1 and goals for BabySeq2 10:30 Potential societal and long-term considerations for those inv…

1
Wish I Knew... with Alannah Frank-Wilson and Erin O’Toole 56:03

3M ago56:03

56:03

Alicia sits down with the newest member of Core Elements, Alannah Frank-Wilson and Erin O’Toole. In this candid conversation, they reflect on the lessons they've learned throughout their counseling careers and share invaluable advice they wish they had known when they started. Dive deep into the topic of compassion fatigue, a common challenge in th…

1
#98 T&J — Your Heroes Are Human, 2 Traits The BEST Climbers Have, Honnold Says The Quiet Thing Out Loud, and Tim Tells Josh His Biggest Mistake 1:56:05

3M ago1:56:05

1:56:05

Tim Kang was just in SLC for the World Cup and NACS. He got to watch and session with some of the best climbers in the world. Hear from Tim what his major takeaways were that can help you too. SHOW NOTES: Honnold’s Comments About Competitions and $ Petzl Roc Trip James-Caro Wedding Present Support the Show. Support us on Patreon: HERE Visit our pod…

1
EP 134: Prenatal genetic testing and the future of AI in genetic counselling with Kira Dineen, host of DNA Today 40:44

4M ago40:44

40:44

0:00 Introduction 1:00 The backstory of how Kira first started DNA Today in 2012, when she was still in high school! 3:30 Some of Kira’s favourite topics she has discussed on DNA Today, including the legacy of Henrietta Lacks, and the story of a Glee actress with down syndrome 10:00 Kira’s best practices for podcasting, from over 10 years of experi…

1
#97 Davin Bagdonas — Alpine Fusion, Grizzly Bears, Developing 1000’s of Climbs World Wide, Chasing The Dragon, and The Call To Adventure 2:12:55

4M ago2:12:55

2:12:55

Davin Bagdonas has developed 1000’s of climbs all over the world. Elite climbers, fellow adventurers, and previous podcast guests, like Jimmy Webb, Jamie Emerson, Roman Yalowitz, Eric Jerome call up Davin when they want to go on a wild adventure to try to find the best boulders in the world. Davin takes us on a trip around the world to places fraug…

1
EP 133: Insights into pharmacogenomics and increasing diversity in genomics research with Dr. Emma Magavern 39:17

4M ago39:17

39:17

0:00 Introduction 2:00 The value of an English Literature degree in designing and analysing research studies in medicine 3:45 Emma’s entrance to pharmacogenomics and her transition from practising physician to genetics research 6:00 How the East London Genes and Health program is increasing representation of diverse populations, namely South Asians…

1
#96 T&J — Battling Mid-Send Doubts, Incredibly Hard Sends, New Shoe Tech, Update Your System By Shutting Up, Don’t Talk Sh!t, and Josh Talk’s Sh!t 1:58:25

4M ago1:58:25

1:58:25

You’re midway through a redpoint burn and you’re tired. There’s a bunch of moves to go and you tell yourself that you’re so tired right now there’s no way you’ll ever send. But the truth is, you have no idea how far you will get or if the send is actually right there for the taking. You can’t trust your feelings! Tim and Josh tackle the problem of …

1
EP 132: From mammoths to genome editing, trailblazing genetics with Dr. George Church 47:41

4M ago47:41

47:41

0:00 Introduction 1:00 George’s upcoming big projects, including developing full recycling, renewing energy, creating bioweather maps, and harnessing citizen science 6:45 Progress in engineering viral resistance in humans, including thoughts from pre- and post- pandemic 11:00 A swapped genetic code that prevents viral infections and gene transfer b…

1
The Healing Power of Sound with Wendy Colby 1:44:04

4M ago1:44:04

1:44:04

In this captivating episode, we delve into the transformative realm of sound therapy with the insightful Wendy Colby. Join us as we explore the profound ways in which sound can nurture, heal, and harmonize the body, mind, and soul. Tune in as Wendy shares her insights into the ancient wisdom of sound, exploring its ability to unlock hidden tensions…

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#95 Palmer Larsen — The Master Coach, Adaptability and Autonomy, Deliberate Practice, Style Then Process, What’s Wrong In Coaching Today, and Olympic 2024 Predictions 2:11:55

4M ago2:11:55

2:11:55

Palmer Larsen is one of the top coaches in the country. This podcast has soooooooooo many helpful tips and frameworks to get you to the next level. DO NOT MISS his description of how to foster an environment for long term success via deliberate practice @ ~1:28! He is the head coach of Momentum Climbing Team, in SLC, one of the top climbing teams i…

1
EP 131: The potential of somatic genomics in drug discovery and development with Jake Rubens 44:57

4M ago44:57

44:57

0:00 Intro 0:40 Jake’s experiences as a serial entrepreneur starting five companies with a basis in genomic science 5:30 Opportunities for research and drug development in the realm of somatic science 9:20 Somatic evolution and how it provides valuable insights into disease mechanisms 12:30 Advantages and disadvantages of studying germline genome-w…

1
Navigating the Emotional Highs & Lows of Parenting 38:54

4M ago38:54

38:54

Hey, wonderful community! Prepare to hit 'play' on our newest podcast episode where Dayna and I explore the emotionally charged world of parenting. Ever feel like your kid just knows how to push those buttons? Yup, we're talking about those moments that trigger us, and let’s be real, it happens to the best of us. But don't fret, because we're also …

1
#94 T&J — How To Approach EVERY Climb, New Era Of Climbing Media, Double Clutching Outside, New Patreon Offering, Warm-Up Projects, Un-Campusing and Why Trying Hard Isn’t Enough 1:52:11

4M ago1:52:11

1:52:11

What is the best way to approach a climb? It’s a simple question that may be one of the most important things to ask yourself before you pull on each time, but it’s never talked about. Tim Kang, professional climber and coach, shares the fundamental strategy needed to get your best performance each time. Announcement!! $5 Patron’s now have access t…

1
EP 130: Quarterly insights into noncoding variants and GWAS with Dr. Veera Rajagopal 51:56

4M ago51:56

51:56

Show Notes: 0:00 Introduction 1:20 How polydactyl mutations can inform research on non-coding variant mechanisms The importance of low-affinity binding between transcription factors and targets How these lessons can help us improve our understanding of drug and target discovery See Veera’s January round-up for more information: https://www.gwasstor…

1
Cracking the Communication Code! 38:21

4M ago38:21

38:21

Hey, lovely souls! It's time to tune in as Dayna and I unpack the mysteries of communication in our latest podcast episode. Ever wonder why sharing our thoughts can feel like navigating a labyrinth? We're dishing out the nitty-gritty on why expressing ourselves can be tough and the pitfalls that can make it even trickier. But hey, it's not all abou…

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#93 Allison Vest — THE STRONGEST FINGERS IN THE WORLD, Hangboarding Deep Dive, Comps Vs Outdoors, LeBron James’ Tip to Send V14, Not Lying to Yourself, Creating FLOAT and Her Secret Training PDF (only ... 2:08:50

5M ago2:08:50

2:08:50

Allison Vest has THE STRONGEST FINGERS IN THE WORLD (according to the internet), and she is finally releasing her secret training plan to us! It’s only $9.99, and the best part is Testpiece listeners get 20% off for a limited time! Get it here NOW! 🥸 Allison shares about what it’s like to climb with the extremely strong fingers and why that’s impor…

1
EP 129: Patient advocacy for genetic ALS and FTD with Jean Swidler, Executive Director of End the Legacy 38:44

5M ago38:44

38:44

0:00 Introduction 0:45 Jean’s personal experiences with family members with genetic ALS 10:00 Jean’s thoughts on the barriers and facilitators to providing treatment for those with genetic ALS 13:20 Insights into C9orf72, a common genetic determinant of ALS, and how it can also be associated with FTD 16:10 Jean’s experiences as an active advocate f…

1
#92 T&J — Climbing At Your Limit, Make It Right USAC, Rants Continue, Gym Field Trips, and The Simplest Effective Training Routine 1:48:03

5M ago1:48:03

1:48:03

Tim Kang and Josh Horsley explore how often to have limit sessions. What limit sessions really mean. And what non-limit sessions look like. They also cover the latest news, give important PSAs, Pro-Tips, and of course there is a rant. There’s always at least one rant. SHOW NOTES: GoFundme for Adriene Felipe Hoo Beastmaking Book Support the Show. Su…

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EP 128: Parkinson’s disease and precision medicine with Drs. James Beck and Ignacio Mata 50:18

5M ago50:18

50:18

0:00 Introduction 1:05 Insights into the PD GENEration’s (a programme from the Parkinson's Foundation) milestones and progress points for the upcoming year 3:30 The shifting attitudes and perspectives of neurologists and healthcare workers at the PD GENEration 5:50 Insights into Nacho’s work with the genetics of Parkinson’s disease 10:20 Barriers a…

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