A Year in Review and a Look to the Future: BTKi in CLL and MCL

CCO Oncology Podcast

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11M ago 27:33

MP3•Pagina principale dell'episodio

In this episode, Ana Marin-Niebla, MD, PhD, and Stephan Stilgenbauer, MD, discuss key trial data on the use of BTK inhibitors in CLL and MCL throughout the past year, how these studies have impacted their practice, and what data they are looking forward to in the near future. The discussion includes analyses of:

SHINE: First-Line Ibrutinib + Bendamustine/Rituximab Followed by Rituximab Maintenance in Older Patients With MCL
TRIANGLE: Ibrutinib + Chemoimmunotherapy With or Without ASCT vs Chemoimmunotherapy Followed by ASCT in Younger Patients with Previously Untreated MCL
ZUMA-2: Brexucabtagene Autoleucel in R/R MCL
BRUIN: Pirtobrutinib for Previously Treated MCL
GLOW: Fixed-Duration Ibrutinib + Venetoclax vs Chlorambucil + Obinutuzumab in Previously Untreated CLL
FLAIR: Ibrutinib + Venetoclax vs FCR in Previously Untreated CLL
ELEVATE-RR: Acalabrutinib vs Ibrutinib in Previously Treated CLL
ALPINE: Zanubrutinib vs Ibrutinib in Previously Treated CLL
BRUIN: Pirtobrutinib for Previously Treated CLL

Presenters:

Ana Marin-Niebla, MD, PhD
Hematology Consultant, Lymphoma Unit
Vall d’Hebron Institute of Oncology, Hematology Department
Hospital Universitario Vall d’Hebron
Barcelona, Spain

Stephan Stilgenbauer, MD
Medical Director Comprehensive Cancer Center Ulm
Head, Early Clinical Trials Unit
Head, Division of CLL Dept. of Internal Medicine III
University Medical Center
Ulm University
Ulm, Germany
Link to full program:
https://bit.ly/3MNaUri

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